Ethyl 3-bromo-2-(methoxyimino)propanoate

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Ethyl 3-bromo-2-(methoxyimino)propanoate
• 英文别名: Ethyl 3-bromo-2-(methoxyimino)-propionate；ethyl 2-methoxyimino-3-bromopropionate；ethyl (2E)-3-bromo-2-methoxyiminopropanoate
• 化学式: C₆H₁₀BrNO₃
• 分子量: 224.054
• InChiKey: HKKNVZIWTKMDLH-YVMONPNESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  47.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Ethyl 3-bromo-2-(methoxyimino)propanoate 在 亚磷酸三乙酯 作用下， 生成 Ethyl 3-(diethoxyphosphinyl)-2-(methoxyimino)propionate
  参考文献：
  名称：

  Processes and intermediates for preparing 3-amino-benzo(b)azepinones

  摘要：

  一种制备上述公式中CCK拮抗剂的方法，其中X、Y.sup.1和Y.sup.2如上所定义，并用于该过程的新型中间体。

  公开号：

  US05977355A1
• 作为产物：
  描述：

  3-溴丙酮酸乙酯 、 甲氧基胺盐酸盐 在 盐酸 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 以93%的产率得到Ethyl 3-bromo-2-(methoxyimino)propanoate
  参考文献：
  名称：

  Processes and intermediates for preparing 3-amino-benzo(b)azepinones

  摘要：

  一种制备上述公式中CCK拮抗剂的方法，其中X、Y.sup.1和Y.sup.2如上所定义，并用于该过程的新型中间体。

  公开号：

  US05977355A1

文献信息

• PESTICIDAL COMPOSITIONS AND RELATED METHODS
  申请人：DOW AGROSCIENCES LLC

  公开号：US20150111732A1

  公开（公告）日：2015-04-23

  A pesticidal composition comprises a 3-(1H-pyrazol)pyridine compound of formula I or any agriculturally acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 9 , R 10 , R 12 , x, n, and Q are as described herein. A method of controlling pests comprises applying the pesticidal composition near a population of pests.

  一种杀虫剂组合物包括式I的3-(1H-吡唑)吡啶化合物或其任何农业上可接受的盐，其中R1、R2、R3、R4、R5、R6、R7、R9、R10、R12、x、n和Q如本文所述。一种控制害虫的方法包括在害虫种群附近施用该杀虫剂组合物。
• Novel substituted pyrazole derivative, process for producing the same, and herbicidal composition containing the same
  申请人：Hirohara Yoji

  公开号：US20050014649A1

  公开（公告）日：2005-01-20

  Substituted pyrazole compounds of the formula (1). The compounds are synthesized from a pyrazole derivative and a haloalkyleneoxime ester derivative, and have excellent herbicidal effects. Herbicide compositions containing the substituted pyrazole derivatives or hydrazide derivatives thereof as active ingredients possess wide herbicidal spectra, work sufficiently in small dosages, and are sufficiently safe for certain important crops.

  公式（1）的取代吡唑化合物。该化合物是由一种吡唑衍生物和一种卤代烷氧肟酯衍生物合成的，具有优异的除草效果。含有取代吡唑衍生物或其肼衍生物作为活性成分的除草剂组合物具有广泛的除草谱，小剂量即可发挥作用，并且对某些重要作物足够安全。
• TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION HAVING AN ANALGESIC ACTIVITY COMPRISING THE SAME
  申请人：Kai Hiroyuki

  公开号：US20130172317A1

  公开（公告）日：2013-07-04

  The present invention provides novel compounds having a P2X 3 and/or P2X 2/3 receptor antagonistic effect. A pharmaceutical composition having an analgesic effect or an improving effect of urination disorder comprising a compound of the formula (I): wherein R h and R j are taken together to form a bond; R a and R b and/or R d and R e are taken together to form oxo or the like; R c is hydrogen, substituted or unsubstituted alkyl or the like; R f is —(CR 4a R 4b ) n —R 2 ; R 4a and R 4b are hydrogen, substituted or unsubstituted alkyl or the like; R 2 is substituted or unsubstituted cycloalkyl or the like; n is an integer of 1 to 4; —R g is —X—R 3 ; —X— is —O—, —S— or the like; R 3 is substituted or unsubstituted cycloalkyl or the like, or its pharmaceutically acceptable salt or a solvate thereof.

  本发明提供了具有P2X3和/或P2X2/3受体拮抗作用的新型化合物。一种具有镇痛作用或改善排尿障碍作用的药物组合物，包括式（I）的化合物：其中Rh和Rj结合形成键；Ra和Rb和/或Rd和Re结合形成氧化物或类似物；Rc是氢、取代或未取代的烷基或类似物；Rf是-(CR4aR4b)n-R2；R4a和R4b是氢、取代或未取代的烷基或类似物；R2是取代或未取代的环烷基或类似物；n是1到4的整数；-R是-X-R3；-X-是-O-、-S-或类似物；R3是取代或未取代的环烷基或类似物，或其药学上可接受的盐或其溶剂化物。
• TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY
  申请人：Shionogi & Co., Ltd.

  公开号：EP2604595A1

  公开（公告）日：2013-06-19

  The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect. A pharmaceutical composition having an analgesic effect or an improving effect of urination disorder comprising a compound of the formula (I): wherein Rh and Rj are taken together to form a bond; Ra and Rb and/or Rd and Re are taken together to form oxo or the like; Rc is hydrogen, substituted or unsubstituted alkyl or the like; Rf is -(CR4aR4b)n-R2; R4a and R4b are hydrogen, substituted or unsubstituted alkyl or the like; R2 is substituted or unsubstituted cycloalkyl or the like; n is an integer of 1 to 4; -Rg is -X-R3; -X- is -O-, -S- or the like; R3 is substituted or unsubstituted cycloalkyl or the like, or its pharmaceutically acceptable salt or a solvate thereof.

  本发明提供了具有 P2X3 和/或 P2X2/3 受体拮抗作用的新型化合物。 一种具有镇痛效果或改善排尿障碍效果的药物组合物，由式（I）化合物组成： 其中 Rh 和 Rj 共同形成键；Ra 和 Rb 和/或 Rd 和 Re 共同形成氧代或类似物；Rc 是氢、取代或未取代的烷基或类似物； Rf是-(CR4aR4b)n-R2；R4a和R4b是氢、取代或未取代的烷基或类似物；R2是取代或未取代的环烷基或类似物；n是1至4的整数；-Rg是-X-R3；-X-是-O-、-S-或类似物；R3是取代或未取代的环烷基或类似物、 或其药学上可接受的盐或其溶液。
• NOVEL SUBSTITUTED PYRAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDAL COMPOSITION CONTAINING THE SAME
  申请人：SDS Biotech K.K.

  公开号：EP1464642B1

  公开（公告）日：2007-08-29