3-Dimethylamino-phthalimid | 6118-66-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 3-Dimethylamino-phthalimid
• 英文别名: 3-dimethylaminophthalimide；4-dimethylamino-isoindole-1,3-dione；4-dimethylamino-isoindoline-1,3-dione；4-Dimethylamino-isoindolin-1,3-dion；4-(dimethylamino)isoindole-1,3-dione
• CAS: 6118-66-7
• 化学式: C₁₀H₁₀N₂O₂
• 分子量: 190.202
• InChiKey: GLAXXBDCGUXCCN-UHFFFAOYSA-N

物化性质

• 熔点：
  148 °C(Solv: water (7732-18-5))
• 密度：
  1.306±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-Dimethylamino-phthalimid 、 氯化钒 在 sodium sulfate 、 尿素 作用下， 以 melt 为溶剂， 以57%的产率得到vanadyl tetra-3-aminophthalocyanine
  参考文献：
  名称：

  Mikhalenko, S. A.; Solov'eva, L. I.; Ivanova, T. M., Journal of general chemistry of the USSR, 1985, vol. 55, p. 986 - 989

  摘要：

  DOI：

文献信息

• ENVIRONMENTALLY SENSITIVE FLUOROPHORES
  申请人：Imperiali Barbara

  公开号：US20100168428A1

  公开（公告）日：2010-07-01

  The present invention generally relates to environment-sensitive fluorophores, including environment-sensitive fluorophores for reporting protein/protein and peptide/protein interactions. In one aspect, the present invention is directed to compounds and salts thereof, compositions and methods useful in determining biological interactions. In some cases, the compounds of the present invention are environment-sensitive fluorophores that have spectroscopic behavior that may depend on factors such as the physicochemical properties of the surrounding environment. The compounds of the present invention can be used, in certain embodiments, to monitor ions, small molecules, and biological processes such as protein folding, protein-protein interactions and phosphorylation events.
• Multimodal Imaging of Fibrin
  申请人：Caravan Peter

  公开号：US20120077958A1

  公开（公告）日：2012-03-29

  Fibrin-specific imaging agents that contain at least two imaging reporters are described, as well as methods of making and using the contrast agents.
• US8440835B2
  申请人：——

  公开号：US8440835B2

  公开（公告）日：2013-05-14
• US9200017B2
  申请人：——

  公开号：US9200017B2

  公开（公告）日：2015-12-01
• US9889213B2
  申请人：——

  公开号：US9889213B2

  公开（公告）日：2018-02-13