4,6-Dimethyl-2-(methylamino)pyrimidin-5-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4,6-Dimethyl-2-(methylamino)pyrimidin-5-ol
• 英文别名: 4,6-dimethyl-2-(methylamino)pyrimidin-5-ol
• 化学式: C₇H₁₁N₃O
• 分子量: 153.18
• InChiKey: HLCQRECXTKMXMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  58
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION
  申请人：VANDERBILT UNIVERSITY

  公开号：US20150368241A1

  公开（公告）日：2015-12-24

  Compounds, compositions and methods related to the prevention or treatment of isoprostane-mediated tissue damage in a mammalian subject in need thereof.

  与哺乳动物受体内异前列腺素介导的组织损伤的预防或治疗相关的化合物、组合物和方法。
• Inhibitors of Hemeprotein-Catalyzed Lipid Peroxidation
  申请人：Vanderbilt University

  公开号：US20160067256A1

  公开（公告）日：2016-03-10

  Methods and compounds for the treatment or prevention of oxidative damage in a mammalian subject. The treatment and/or prevention may be on inhibiting heme-induced lipid peroxidation. Also discloses are methods and compounds for treating or preventing isoprostane-mediated tissue damage.
• US9545385B2
  申请人：——

  公开号：US9545385B2

  公开（公告）日：2017-01-17
• [EN] INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION<br/>[FR] INHIBITEURS DE PEROXYDATION LIPIDIQUE CATALYSÉE PAR HÉMOPROTÉINE
  申请人：UNIV VANDERBILT

  公开号：WO2014124059A2

  公开（公告）日：2014-08-14

  Compounds, compositions and methods related to the prevention or treatment of isoprostane-mediated tissue damage in a mammalian subject in need thereof.