9-methyl-3,4,6,7,8,9-hexahydro-2H-pyridazino[1,2-a]triazin-10-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 9-methyl-3,4,6,7,8,9-hexahydro-2H-pyridazino[1,2-a]triazin-10-ium
• 化学式: C8H16N3+
• 分子量: 154.23
• InChiKey: BSWJMLQBZMCYLQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PREPARATION OF PHARMACEUTICAL SALTS OF 3-O-(3',3'-DIMETHLSUCCINYL) BETULINIC ACID
  申请人：Panacos Pharmaceuticals, Inc.

  公开号：EP1968606A2

  公开（公告）日：2008-09-17
• Preparation of pharmaceutical salts of 3-O-(3',3'-dimethylsuccinyl)betulinic acid
  申请人：Hemp Christian

  公开号：US20070203103A1

  公开（公告）日：2007-08-30

  This invention relates to a novel process for making 3-O-(3′,3′-dimethylsuccinyl)betulinic acid (“DSB”). This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.
• Preparation of Pharmaceutical Salts of 3-0-(3',3'-Dimethylsuccinyl) Betulinic Acid
  申请人：Hemp Christian

  公开号：US20110313191A1

  公开（公告）日：2011-12-22

  This invention relates to a novel process for making 3-O-(3′,3′-dimethylsuccinyl)betulinic acid (“DSB”). This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.
• [EN] PREPARATION OF PHARMACEUTICAL SALTS OF 3-O-(3',3'-DIMETHLSUCCINYL) BETULINIC ACID<br/>[FR] PRÉPARATION DE SELS PHARMACEUTIQUES DE L'ACIDE 3-O-(3',3'-DIMÉTHYLSUCCINYL)BÉTULINIQUE
  申请人：HEMP CHRISTIAN

  公开号：WO2007078848A2

  公开（公告）日：2007-07-12

  [EN] This invention relates to a novel process for making 3-O-(3',3'- dimethylsuccinyl)betulinic acid ("DSB")- This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.
  [FR] L'invention concerne un nouveau procédé de préparation d'acide 3-O-(3',3'-diméthylsuccinyl)bétulinique ("DSB"), ainsi que des procédés de traitement du VIH et de pathologies apparentées en utilisant des compositions pharmaceutiques qui comprennent des formes sels du DSB préparées suivant le procédé de la présente invention. L'invention concerne en outre des formes de doses de compositions pharmaceutiques comprenant des sels de DSB produits en utilisant le procédé de l'invention.