5-Brom-6-methoxy-5,6-dihydrouracil | 59411-67-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-Brom-6-methoxy-5,6-dihydrouracil
• 英文别名: 5-bromo-6-methoxy-5-methyl-dihydro-pyrimidine-2,4-dione；5-Brom-6-methoxy-5-methyl-dihydro-pyrimidin-2,4-dion；5-Bromo-6-methoxy-5-methyldihydropyrimidine-2,4(1H,3H)-dione；5-bromo-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
• CAS: 59411-67-5
• 化学式: C₆H₉BrN₂O₃
• 分子量: 237.053
• InChiKey: CMMVZKLZJCDEIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  67.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-Brom-6-methoxy-5,6-dihydrouracil 在 silver(l) oxide 作用下， 生成 Bis-<6-methoxy-5.6-dihydro-thym-5-yl>-ether
  参考文献：
  名称：

  Identification of the Ndh (NAD(P)H-Plastoquinone-oxidoreductase) Complex in Etioplast Membranes of Barley: Changes during Photomorphogenesis of Chloroplasts

  摘要：

  近年来，人们已经充分证实，叶绿体类囊体膜中存在一种与线粒体复合体I同源的NAD(P)H-类脂醌氧化还原酶复合物（Ndh复合物）。在此，我们报告了在大麦色素体膜中鉴定出Ndh复合物。与来自绿色叶绿体的类囊体膜相比，色素体膜中Ndh复合物的两种类囊体DNA编码的多肽（NDH-A和NDH-F）相对更丰富。在黑暗中生长的大麦幼苗经光照后，色素体转化为叶绿体，伴随着类囊体膜相关NADH脱氢酶活性的降低。我们使用原位-PAGE和免疫标记技术确定，与类囊体膜相关的NADH特异性脱氢酶活性在色素体中比在绿色叶绿体中更活跃，其中包含NDH-A和NDH-F多肽。这些结果与通过蓝原-PAGE获得的结果相辅相成，表明NDH-A和NDH-F多肽是色素体膜中580 kDa NADH依赖性脱氢酶复合物的一部分。这一发现证明Ndh复合物的积累与光照无关。在色素体向叶绿体过渡期间，该复合物的相对水平和特异性活性降低，伴随着类囊体膜相关过氧化物酶特异性活性的

  DOI：

  10.1093/pcp/41.1.49
• 作为产物：
  描述：

  胸腺嘧啶 在 甲醇 、 溴 作用下， 生成 5-Brom-6-methoxy-5,6-dihydrouracil
  参考文献：
  名称：

  Kurtew; Dimitrov, Doklady Bolgarskoi Akademii Nauk, 1953, vol. 6, # 1, p. 17,18

  摘要：

  DOI：

文献信息

• Identification of the Ndh (NAD(P)H-Plastoquinone-oxidoreductase) Complex in Etioplast Membranes of Barley: Changes during Photomorphogenesis of Chloroplasts
  作者：A. Guera、P. G. de Nova、B. Sabater

  DOI：10.1093/pcp/41.1.49

  日期：2000.1.1

  In the last few years the presence in thylakoid membranes of chloroplasts of a NAD(P)H-plastoquinone oxidoreductase complex (Ndh complex) homologous to mitochondrial complex I has been well established. Herein, we report the identification of the Ndh complex in barley etioplast membranes. Two plastid DNA-encoded polypeptides of the Ndh complex (NDH-A and NDH-F) were relatively more abundant in etioplast membranes than in thylakoids from greening chloroplasts. Conversion of etioplast into chloroplast, after light exposure of barley seedlings grown in the dark, was accompanied by a decrease in the NADH dehydrogenase activity associated to plastid membranes. Using native-PAGE and immunolabelling techniques we have determined that a NADH specific dehydrogenase activity associated with plastid membranes, which was more active in etioplasts than in greening chloroplasts, contained the NDH-A and NDH-F polypeptides. These results complemented by those obtained through blue-native-PAGE indicated that NDH-A and NDH-F polypeptides are part of a 580 kDa NADH dependent dehydrogenase complex present in etioplast membranes. This finding proves that accumulation of the Ndh complex is independent of light. The decrease in the relative levels and specific activity of this complex during the transition from etioplast to chloroplasts was accompanied by a parallel decrease in the specific activity of peroxidase associated to plastid membranes. Based on the mentioned observations it is proposed that an electron transport chain from NADH to H2O2 could be active in barley etioplasts.

  近年来，人们已经充分证实，叶绿体类囊体膜中存在一种与线粒体复合体I同源的NAD(P)H-类脂醌氧化还原酶复合物（Ndh复合物）。在此，我们报告了在大麦色素体膜中鉴定出Ndh复合物。与来自绿色叶绿体的类囊体膜相比，色素体膜中Ndh复合物的两种类囊体DNA编码的多肽（NDH-A和NDH-F）相对更丰富。在黑暗中生长的大麦幼苗经光照后，色素体转化为叶绿体，伴随着类囊体膜相关NADH脱氢酶活性的降低。我们使用原位-PAGE和免疫标记技术确定，与类囊体膜相关的NADH特异性脱氢酶活性在色素体中比在绿色叶绿体中更活跃，其中包含NDH-A和NDH-F多肽。这些结果与通过蓝原-PAGE获得的结果相辅相成，表明NDH-A和NDH-F多肽是色素体膜中580 kDa NADH依赖性脱氢酶复合物的一部分。这一发现证明Ndh复合物的积累与光照无关。在色素体向叶绿体过渡期间，该复合物的相对水平和特异性活性降低，伴随着类囊体膜相关过氧化物酶特异性活性的
• Kurtew; Dimitrov, Doklady Bolgarskoi Akademii Nauk, 1953, vol. 6, # 1, p. 17,18
  作者：Kurtew、Dimitrov

  DOI：——

  日期：——