N-(4-methyl-2-oxochromen-7-yl)-4-oxobutanamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: N-(4-methyl-2-oxochromen-7-yl)-4-oxobutanamide
• 化学式: C₁₄H₁₃NO₄
• 分子量: 259.26
• InChiKey: WIWLRAHEKNMDFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  72.5
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] FLUORESCENT ANTICANCER PLATINUM DRUGS<br/>[FR] MÉDICAMENTS ANTICANCÉREUX FLUORESCENTS AU PLATINE
  申请人：INVICTUS ONCOLOGY PVT LTD

  公开号：WO2017064657A1

  公开（公告）日：2017-04-20

  The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.