3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzyl alcohol | 1234623-96-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzyl alcohol
• 英文别名: [4-[(2-Chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl]methanol；[4-[(2-chloro-1,3-thiazol-5-yl)methoxy]-3-methoxyphenyl]methanol
• CAS: 1234623-96-1
• 化学式: C₁₂H₁₂ClNO₃S
• 分子量: 285.751
• InChiKey: KWAPQSUOGVBFRM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzyl alcohol 在 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 以84.5%的产率得到3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzyl chloride
  参考文献：
  名称：

  Synthesis and herbicidal activities of 2-cyano-3-benzylaminoacrylates containing thiazole moiety

  摘要：

  Two series of novel 2-cyano-3-benzylaminoacrylates containing long-chain thiazole ring moiety were synthesized as herbicidal inhibitors of photosystem II (PS II) electron transportation. Their structures were confirmed by (1)H NMR and elemental analysis. The bioassay showed that these compounds retain high herbicidal activities and especially compounds 13a and 13h have excellent herbicidal activities. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.04.027
• 作为产物：
  描述：

  3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzaldehyde 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 以92.1%的产率得到3-methoxy-4-((2-chlorothiazol-5-yl)methoxy)benzyl alcohol
  参考文献：
  名称：

  Synthesis and herbicidal activities of 2-cyano-3-benzylaminoacrylates containing thiazole moiety

  摘要：

  Two series of novel 2-cyano-3-benzylaminoacrylates containing long-chain thiazole ring moiety were synthesized as herbicidal inhibitors of photosystem II (PS II) electron transportation. Their structures were confirmed by (1)H NMR and elemental analysis. The bioassay showed that these compounds retain high herbicidal activities and especially compounds 13a and 13h have excellent herbicidal activities. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.04.027

文献信息

• Synthesis and herbicidal activities of 2-cyano-3-benzylaminoacrylates containing thiazole moiety
  作者：Tingting Wang、Guifang Bing、Xin Zhang、Zhenfang Qin、Haibo Yu、Xue Qin、Hong Dai、Wenke Miao、Shanshan Wu、Jianxin Fang

  DOI：10.1016/j.bmcl.2010.04.027

  日期：2010.6

  Two series of novel 2-cyano-3-benzylaminoacrylates containing long-chain thiazole ring moiety were synthesized as herbicidal inhibitors of photosystem II (PS II) electron transportation. Their structures were confirmed by (1)H NMR and elemental analysis. The bioassay showed that these compounds retain high herbicidal activities and especially compounds 13a and 13h have excellent herbicidal activities. (C) 2010 Elsevier Ltd. All rights reserved.