hydron;3-(2-methylpiperidin-1-yl)propyl 4-cyclohexyloxybenzoate;chloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hydron;3-(2-methylpiperidin-1-yl)propyl 4-cyclohexyloxybenzoate;chloride
• 化学式: C22H34ClNO3
• 分子量: 396.0
• InChiKey: UFWWXJRCWHOHOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.24
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  38.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Anti-infective compositions, methods and systems for treating disordered tissue
  申请人：——

  公开号：US20020188028A1

  公开（公告）日：2002-12-12

  The present invention relates to the treatment of disordered epithelial tissues such as cold sores and other complications resulting from disorders such as herpes, and the like. The invention relates to the use of an anti-infective and/or antimicrobial active agent in a carrier, with vigorous agitation of the disordered epithelial tissue for topical treatment thereof under such conditions sufficient to achieve clinically discernable improvement of the disordered epithelial tissue. The preferred anti-infective and/or antimicrobial active agent comprises an organohalide, such as a quaternary ammonium compound, preferably benzalkonium chloride. The inventive method may be used also in connection with a preferred applicator configuration.

  本发明涉及治疗紊乱的上皮组织，如唇疱疹和疱疹等疾病引起的其他并发症。本发明涉及在载体中使用抗感染和/或抗菌活性剂，在足以使紊乱的上皮组织得到临床上可辨认的改善的条件下，对紊乱的上皮组织进行剧烈搅拌，以进行局部治疗。优选的抗感染和/或抗菌活性剂包括有机卤化物，如季铵盐化合物，最好是苯扎氯铵。本发明的方法也可用于优选的涂抹器配置。
• Anti-infective compositions, methods and systems for treating pathogen-induced disordered tissues
  申请人：——

  公开号：US20040186183A1

  公开（公告）日：2004-09-23

  Compositions, methods and systems for treating disordered epithelial tissues, such as is caused by pathogens and/or by toxins produced thereby. The invention relates to the use of an anti-infective and/or antimicrobial active agent in a carrier, with vigorous agitation of the disordered epithelial tissue for topical treatment thereof under such conditions sufficient to achieve clinically discernable improvement of the disordered epithelial tissue. The preferred anti-infective and/or antimicrobial active agent comprises an organohalide, such as a quaternary ammonium halide compound, preferably benzalkonium chloride. The inventive compositions and methods may employ the use of an applicator adapted for use in promoting the penetration of the treatment composition and/or the vigorous agitation of the disordered tissue.

  用于治疗紊乱上皮组织的组合物、方法和系统，例如由病原体和/或由此产生的毒素引起的紊乱上皮组织。本发明涉及在载体中使用抗感染和/或抗菌活性剂，并对紊乱的上皮组织进行剧烈搅拌，在足以使紊乱的上皮组织得到临床上可识别的改善的条件下进行局部治疗。优选的抗感染和/或抗菌活性剂包括有机卤化物，如季铵盐化合物，最好是苯扎氯铵。本发明的组合物和方法可以使用适用于促进治疗组合物渗透和/或剧烈搅拌紊乱组织的涂抹器。
• SYSTEMS FOR AGITATED DELIVERY OF ANTI-INFECTIVE COMPOSITIONS TO TREAT DISORDERED TISSUE SUCH AS COLD SORES
  申请人：Johnson, B. Ron

  公开号：EP1214064A1

  公开（公告）日：2002-06-19
• EP1214064A4
  申请人：——

  公开号：EP1214064A4

  公开（公告）日：2006-01-18
• ANTI-INFECTIVE COMPOSITIONS FOR TREATING DISORDERED TISSUE SUCH AS COLD SORES
  申请人：Johnson, B. Ron

  公开号：EP1404174A2

  公开（公告）日：2004-04-07