R(-)-N-烯丙基去甲阿朴吗啡氢溴酸盐 | 18426-17-0

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 阿朴菲
• 中文名称: R(-)-N-烯丙基去甲阿朴吗啡氢溴酸盐
• 英文名称: (R)-6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
• 英文别名: (6aR)-6-prop-2-enyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
• CAS: 18426-17-0
• 化学式: C₁₉H₁₉NO₂
• 分子量: 293.4
• InChiKey: XEXUKNQDDPKEIF-OAHLLOKOSA-N

物化性质

• 溶解度：
  H2O：0.29 mg/mL

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  43.7
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• WGK Germany：
  3
• 海关编码：
  2933990090

文献信息

• METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION
  申请人：Quake Stephen R.

  公开号：US20100260717A1

  公开（公告）日：2010-10-14

  Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of identifying a candidate agent for the treatment of hepatitis C virus (HCV) infection, and the like.
• DNA CYTOSINE DEAMINASE INHIBITORS
  申请人：Harris Reuben S.

  公开号：US20110218158A1

  公开（公告）日：2011-09-08

  Cytosine deaminase inhibitors and methods for identifying inhibitors of the anti-retroviral activity of APOBEC3G are described.
• US8895598B2
  申请人：——

  公开号：US8895598B2

  公开（公告）日：2014-11-25
• [EN] METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION<br/>[FR] PROCÉDÉS DE TRAITEMENT D'UNE INFECTION PAR UN VIRUS DE LA FAMILLE DES FLAVIVIRIDAE, COMPOSITIONS POUR TRAITER UNE INFECTION PAR UN VIRUS DE LA FAMILLE DES FLAVIVIRIDAE, ET TESTS D'IDENTIFICATION PAR CRIBLAGE DES COMPOSITIONS POUR TRAITE
  申请人：UNIV STANFORD

  公开号：WO2009039246A2

  公开（公告）日：2009-03-26

  Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of identifying a candidate agent for the treatment of hepatitis C virus (HCV) infection, and the like.
• [EN] DNA CYTOSINE DEAMINASE INHIBITORS<br/>[FR] INHIBITEURS DE LA CYTOSINE DÉSAMINASE D'UN ADN
  申请人：UNIV MINNESOTA

  公开号：WO2010033986A2

  公开（公告）日：2010-03-25

  Cytosine deaminase inhibitors and methods for identifying inhibitors of the anti-retroviral activity of APOBEC3G are described.