2-Benzylamino-Δ²-oxazolin | 65536-79-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Benzylamino-Δ²-oxazolin
• 英文别名: 2-Benzylamino-oxazolin；benzyl-(4,5-dihydro-oxazol-2-yl)-amine；Benzylamine, N-(2-oxazolinyl)-；N-benzyl-4,5-dihydro-1,3-oxazol-2-amine
• CAS: 65536-79-0
• 化学式: C₁₀H₁₂N₂O
• 分子量: 176.218
• InChiKey: DBCGDMLNSRGMLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  33.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Benzylamino-Δ²-oxazolin 以 四氢呋喃 为溶剂， 生成 N-benzylaminocarbonyl N-(2-chloroethyl) O-ethyl S-propyl phosphoramidothioate
  参考文献：
  名称：

  N-(Substituted)aminocarbonyl O,S-dialkyl phosphoramido(di)thioates and

  摘要：

  这项发明涉及以下结构的新型磷酰胺(二)硫酸酯：其中A为A.卤素原子，B.氰基，C.(C.sub.1 -C.sub.6)烷氧基，D.(C.sub.1 -C.sub.6)烷基硫基，E.(C.sub.1 -C.sub.6)烷基羰氧基，F.苯氧基，或G.苯硫基；R.sup.1为A.(C.sub.1 -C.sub.12)烷基，B.(C.sub.3 -C.sub.8)环烷基，C.最多含有11个碳原子的可选择取代的芳基烷基，或D.可选择取代的(C.sub.6 -C.sub.10)芳基；R.sup.2为卤素原子时为氢原子或(C.sub.1 -C.sub.4)烷基；当A不是卤素原子时为氢原子；R.sup.3为(C.sub.1 -C.sub.6)烷基；R.sup.4为(C.sub.1 -C.sub.6)烷基；R.sup.5和R.sup.6独立地为氢原子或(C.sub.1 -C.sub.4)烷基；Y为氧原子或硫原子；以及包含它们的组合物、制备它们的方法以及将它们用作杀虫剂的方法。

  公开号：

  US04059697A1

文献信息

• [EN] PYRROLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS<br/>[FR] COMPOSÉS PYRROLIN-2-YLAMINO DESTINÉS À COMBATTRE LES ANIMAUX NUISIBLES
  申请人：BASF SE

  公开号：WO2010029069A1

  公开（公告）日：2010-03-18

  The present invention relates to pyrrolin-2-ylamino compounds for combating animal pests. The invention also relates to a method for controlling animal pests by using these compounds, to plant propagation material and to an agricultural composition comprising said compounds. The invention also relates to a method for treating or protecting an animal from infestation or infection by parasites by using said compounds. Formula (I) wherein n is 0, 1, 2, 3, 4 or 5; m is 0, 1, 2, 3, 4 or 5; R1, R2 are each independently selected from the group consisting of: halogen, CN, N3, NO2, C1-C6-alkyl, C2-C6-alkenyl and C2-C6-alkynyl, where the last 3 radicals mentioned may be partly or completely halogenated and/or may carry any combination of 1, 2 or 3 radicals R#, etc.; R3 and R4 are selected each independently of one another from hydrogen, halogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, wherein the last 3 radicals mentioned may be partly or completely halogenated and/or may carry any combination of 1, 2 or 3 radicals selected independently of one another from the group consisting of CN, NO2, -ORb, NRcRd, -SRe, -C(=O)Ra and -C(=O)ORb, etc.; A is a radical of the formulae A.1 or A.2, wherein * indicates the point of attachment to the remaining part of the compound; R5a, R5b, R5c, R5d, R5e and R5f are selected independently from one another from hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylamino, di(C1-C6-alkyl)amino, C3-C6- cycloalkyl and Ar2, etc.; R6 and R7 are selected each independently from one another from hydrogen, CN, NO2, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, saturated or partially unsaturated 5-, 6- or 7-membered heterocyclic radicals, Ar3, etc.

  本发明涉及用于对抗动物害虫的吡咯啉-2-基氨基化合物。该发明还涉及一种通过使用这些化合物来控制动物害虫的方法，以及包括所述化合物的植物繁殖材料和农业组合物。该发明还涉及一种通过使用这些化合物来治疗或保护动物免受寄生虫感染的方法。其中，公式（I）中n为0、1、2、3、4或5；m为0、1、2、3、4或5；R1、R2分别独立选择自卤素、CN、N3、NO2、C1-C6-烷基、C2-C6-烯基和C2-C6-炔基等的基团；R3和R4各自独立选择自氢、卤素、C1-C6-烷基、C2-C6-烯基、C2-C6-炔基等的基团，其中最后提到的3个基团可能部分或完全卤代，和/或可能携带任意组合的1、2或3个基团R#等；A是公式A.1或A.2的基团，其中*表示与化合物其余部分的连接点；R5a、R5b、R5c、R5d、R5e和R5f各自独立选择自氢、卤素、C1-C6-烷基、C1-C6-烷氧基、C1-C6-烷基氨基、双（C1-C6-烷基）氨基、C3-C6-环烷基和Ar2等的基团；R6和R7各自独立选择自氢、CN、NO2、C1-C6-烷基、C2-C6-烯基、C2-C6-炔基、C3-C8-环烷基、饱和或部分不饱和的5、6或7-成员杂环基团、Ar3等的基团。
• [EN] AZOLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS<br/>[FR] COMPOSÉS AZOLIN-2-YLAMINO POUR LUTTER CONTRE DES ANIMAUX NUISIBLES
  申请人：BASF SE

  公开号：WO2009115491A1

  公开（公告）日：2009-09-24

  The present invention relates to azolin-2-ylamino compounds of formulae (I) and (II), wherein n is 0 to 3; Ar is phenyl; A is a radical of formulae A1 or A2, wherein * indicates the point of attachment; X is S, O or N(R10); R7a-d are H, halogen, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylamino or C3-C6-cycloalkyl; R8-10 are H, CN, NO2, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, Ar3, -B-C(=O)Ra, -B-C(=S)Ra, -B-C(=NRf)Ra, etc., wherein B is a single bond or C1-C4-alkanediyl; R1 is H, halogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl, phenyl or benzyl; R2,3 are H, halogen, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C6-cycloalkyl, phenyl or benzyl; R4 is H, halogen, CN, N3, NO2, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, a heterocycle, Ar5, -C(=O)Ra, -C(=S)Ra, -C(=NRf)Ra, etc.; or R4 and R5 together form a carbocycle or heterocycle; R5,6 are H, halogen, CN, N3, NO2, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, heterocycle, Ar8, -C(=O)Ra, -C(=S)Ra, -C(=NRf)Ra, etc.; or R5 and R6 together form a carbocycle or heterocycle; Ra-h are H, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, heterocycles or Ar10; Ar1 to 11 are phenyl, naphthyl or heteroaryl; and A' is a radical of formula A3, wherein W is halogen or OR11; R11 is H or -C(=O)-Ri; Ri is H, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, heterocycle or Ar12; and Ar12 is phenyl, naphthyl or heteroaryl; as well as to agricultural composition containing such compounds, the use of such compounds for controlling animal pests, seed, comprising such compounds, a method for controlling animal pests and a method for treating or protecting an animal from infestation or infection by parasites.

  本发明涉及式（I）和（II）的噻唑啉-2-基氨基化合物，其中n为0至3；Ar为苯基；A为式A1或A2的基团，其中*表示连接点；X为S、O或N(R10)；R7a-d为H、卤素、C1-C6-烷基、C1-C6-烷氧基、C1-C6-烷基氨基或C3-C6环烷基；R8-10为H、CN、NO2、C1-C6-烷基、C2-C6-烯基、C2-C6-炔基、C3-C8环烷基、Ar3、-B-C(=O)Ra、-B-C(=S)Ra、-B-C(=NRf)Ra等，其中B为单键或C1-C4烷二基；R1为H、卤素、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C6环烷基、苯基或苄基；R2,3为H、卤素、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C6环烷基、苯基或苄基；R4为H、卤素、CN、N3、NO2、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C8环烷基、杂环、Ar5、-C(=O)Ra、-C(=S)Ra、-C(=NRf)Ra等；或R4和R5一起形成碳环或杂环；R5,6为H、卤素、CN、N3、NO2、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C8环烷基、杂环、Ar8、-C(=O)Ra、-C(=S)Ra、-C(=NRf)Ra等；或R5和R6一起形成碳环或杂环；Ra-h为H、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C8环烷基、杂环或Ar10；Ar1至11为苯基、萘基或杂环基；A'为式A3的基团，其中W为卤素或OR11；R11为H或-C(=O)-Ri；Ri为H、C1-C6烷基、C2-C6-烯基、C2-C6-炔基、C3-C8环烷基、杂环或Ar12；Ar12为苯基、萘基或杂环基；以及含有这种化合物的农业组合物，使用这种化合物控制动物害虫的方法，包括这种化合物的种子，控制动物害虫的方法以及治疗或保护动物免受寄生虫感染的方法。
• Insecticidal Substituted Benzylamino Heterocyclic and Heteroaryl Derivatives
  申请人：Dixson John A.

  公开号：US20090036306A1

  公开（公告）日：2009-02-05

  Certain substituted benzylamino heterocyclic and heteroaryl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (1): wherein R, R1, R2, R3, and R4 are fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula (1), and optionally, an effective amount of at least one of an additional compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

  某些取代苯基氨基的杂环和杂环芳基衍生物具有出乎意料的杀虫和杀螨活性。这些化合物由公式(1)表示:其中R、R1、R2、R3和R4在此完整描述。此外，还公开了包含公式(1)中至少一种化合物的杀虫有效量的组合物，以及可选地，至少一种附加化合物的有效量，与至少一种杀虫兼容载体的组合物;以及控制昆虫的方法，包括将所述组合物应用于昆虫存在或预计存在的地点。
• Pyrrolin-2-ylamino Compounds For Combating Animal Pests
  申请人：Paulini Ralph

  公开号：US20110160269A1

  公开（公告）日：2011-06-30

  The present invention relates to pyrrolin-2-ylamino compounds for combating animal pests. The invention also relates to a method for controlling animal pests by using these compounds, to plant propagation material and to an agricultural composition comprising said compounds. The invention also relates to a method for treating or protecting an animal from infestation or infection by parasites by using said compounds. wherein n is 0, 1, 2, 3, 4 or 5; m is 0, 1, 2, 3, 4 or 5; R 1 , R 2 are each independently selected from the group consisting of: halogen, CN, N 3 , NO 2 , C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl and C 2 -C 6 -alkynyl, where the last 3 radicals mentioned may be partly or completely halogenated and/or may carry any combination of 1, 2 or 3 radicals R # , etc.; R 3 and R 4 are selected each independently of one another from hydrogen, halogen, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, wherein the last 3 radicals mentioned may be partly or completely halogenated and/or may carry any combination of 1, 2 or 3 radicals selected independently of one another from the group consisting of CN, NO 2 , —OR b , NR c R d , —SR e , —C(═O)R a and —C(═O)OR b , etc.; A is a radical of the formulae A.1 or A.2, wherein * indicates the point of attachment to the remaining part of the compound; R 5a , R 5b , R 5c , R 5d , R 5e and R 5f are selected independently from one another from hydrogen, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylamino, di(C 1 -C 6 -alkyl)amino, C 3 -C 6 -cycloalkyl and Ar 2 , etc.; R 6 and R 7 are selected each independently from one another from hydrogen, CN, NO 2 , C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 3 -C 8 -cycloalkyl, saturated or partially unsaturated 5-, 6- or 7-membered heterocyclic radicals, Ar 3 , etc.

  本发明涉及用于对抗动物害虫的吡咯啉-2-基氨基化合物。本发明还涉及使用这些化合物控制动物害虫的方法，以及植物繁殖材料和包含该化合物的农业组合物。本发明还涉及使用该化合物治疗或保护动物免受寄生虫感染或侵染的方法。其中n为0、1、2、3、4或5；m为0、1、2、3、4或5；R1、R2各自独立地选择自卤素、CN、N3、NO2、C1-C6烷基、C2-C6烯基和C2-C6炔基的群体，其中最后3个提到的基团可能部分或完全卤代，并/或可能携带任意组合的1、2或3个基团R#等；R3和R4各自独立地选择自氢、卤素、C1-C6烷基、C2-C6烯基、C2-C6炔基的群体，其中最后3个提到的基团可能部分或完全卤代，并/或可能携带任意组合的1、2或3个基团，这些基团各自独立地选择自CN、NO2、-ORb、NRcRd、-SRe、-C（=O）Ra和-C（=O）ORb等；A是式A.1或A.2的基团，其中*表示与化合物其余部分的连接点；R5a、R5b、R5c、R5d、R5e和R5f各自独立地选择自氢、卤素、C1-C6烷基、C1-C6烷氧基、C1-C6烷基氨基、二（C1-C6烷基）氨基、C3-C6环烷基和Ar2等；R6和R7各自独立地选择自氢、CN、NO2、C1-C6烷基、C2-C6烯基、C2-C6炔基、C3-C8环烷基、饱和或部分不饱和的5、6或7元杂环基、Ar3等。
• INSECTICIDAL SUBSTITUTED BENZYLAMINO HETEROCYCLIC AND HETEROARYL DERIVATIVES
  申请人：Bayer CropScience AG

  公开号：EP1885180A2

  公开（公告）日：2008-02-13