Toluene, trifluoro-

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Toluene, trifluoro-
• 英文别名: 1,2-difluoro-3-(fluoromethyl)benzene
• 化学式: C₇H₅F₃
• 分子量: 146.11
• InChiKey: QCUDEATVOVLIKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  、 Toluene, trifluoro- 、 N-甲基-3-氨基吡唑 、 4-氯喹唑啉-6-醇 生成 6-[2-fluoro-6-(fluoromethyl)-phenoxy]-N-(1-methyl-1H-pyrazol-3-yl)quinazolin-4-yl-amine
  参考文献：
  名称：

  Substituted quinazoline or pyridopyrimidine derivative

  摘要：

  本发明提供了一种具有激活葡萄糖激酶作用的化合物，其表示为式（I）：X为氮原子等；Y为氧原子等；R1为可选取代的五到六元杂环芳基等；R2为氢原子或氟原子；环A为单环或双环杂环芳基，其可以具有由式（II）表示的取代基，或其药学上可接受的盐，用于预防或治疗糖尿病等。

  公开号：

  US07687502B2

文献信息

• Substituted Quinazoline or Pyridopyrimidine Derivative
  申请人：Mitsuya Morihiro

  公开号：US20080032996A1

  公开（公告）日：2008-02-07

  The present invention provides a compound having a glucokinase activating action being useful for prevention or treatment of diabetes mellitus, etc. being represented by the formula (I): X is nitrogen atom, etc.; Y is oxygen atom, etc.; R 1 is an optionally substituted five to six-membered heteroaryl group, etc.; R 2 is hydrogen atom or fluorine atom; and ring A is a monocyclic or bicyclic heteroaryl group which may have a substituent represented by the formula (II)] or a pharmaceutically acceptable salt thereof.

  本发明提供了一种具有激活葡萄糖激酶作用的化合物，该化合物可用于预防或治疗糖尿病等疾病，其表示式为(I)：其中，X为氮原子等；Y为氧原子等；R1为可选取代的五至六元杂环芳基基团等；R2为氢原子或氟原子；环A为单环或双环杂环芳基基团，其可具有由式(II)表示的取代基，或其药学上可接受的盐。
• SUBSTITUTED QUINAZOLINE OR PYRIDOPYRIMIDINE DERIVATIVE
  申请人：BANYU PHARMACEUTICAL CO., LTD.

  公开号：EP1734040A1

  公开（公告）日：2006-12-20

  The present invention provides a compound having a glucokinase activating action being useful for prevention or treatment of diabetes mellitus, etc. being represented by the formula (I): X is nitrogen atom, etc.; Y is oxygen atom, etc.; R1 is an optionally substituted five to six-membered heteroaryl group, etc.; R2 is hydrogen atom or fluorine atom; and ring A is a monocyclic or bicyclic heteroaryl group which may have a substituent represented by the formula (II)] or a pharmaceutically acceptable salt thereof.

  本发明提供了一种具有葡萄糖激酶激活作用的化合物，可用于预防或治疗糖尿病等，由式（I）表示： X为氮原子等；Y为氧原子等；R1为任选取代的五至六元杂芳基等；R2为氢原子或氟原子；环A为单环或双环杂芳基，可具有由式(II)代表的取代基]。 或其药学上可接受的盐。
• Negative electrode for a rechargeable lithium battery and material compostion for fabrication the same
  申请人：Samsung SDI Co., Ltd.

  公开号：EP1928047A1

  公开（公告）日：2008-06-04

  The present invention relates to negative electrode for rechargeable lithium batteries, rechargeable lithium batteries including the same, and a negative active material composition for fabrication of the negative electrode. According to one aspect of the invention, there is provided a negative electrode for a rechargeable lithium battery. The inventive negative electrode has a current collector and a negative active material layer on the current collector, which comprises a negative active material and a polyimide binder. The negative active material layer further comprises at least one flexible polymer.

  本发明涉及可充电锂电池的负极、包括其在内的可充电锂电池以及用于制造负极的负极活性材料组合物。根据本发明的一个方面，提供了一种用于可充电锂电池的负极。本发明的负极具有集流器和集流器上的负极活性材料层，该层包括负极活性材料和聚酰亚胺粘合剂。负极活性材料层还包括至少一种柔性聚合物。
• SWELLING TAPE FOR FILLING GAP
  申请人：LG Chem, Ltd.

  公开号：EP2657310A2

  公开（公告）日：2013-10-30

  A swelling tape for filling a gap and a method of filling a gap are provided. The swelling tape can be applied within the gap having a fluid to realize a 3D shape thereby filling the gap, and be used to fix a subject forming the gap as necessary.

  本文提供了一种用于填充缝隙的膨胀胶带和一种填充缝隙的方法。膨胀胶带可贴在有液体的缝隙内，实现三维形状，从而填充缝隙，并在必要时用于固定形成缝隙的物体。
• ELECTRODE ASSEMBLY BODY
  申请人：LG Chem, Ltd.

  公开号：EP2658025A2

  公开（公告）日：2013-10-30

  An electrode assembly and a battery are provided. The electrode assembly may be effectively fixed inside a can as a pressure-sensitive adhesive tape attached to an outer circumferential surface of the electrode assembly is formed into a 3D shape by an electrolyte. Thus, the electrode assembly does not move and rotate inside the can due to external vibration or impact and damage of welded regions of a tab or disconnection of inner circuits can be prevented.

  提供了一种电极组件和电池。电极组件可有效固定在罐内，因为电极组件外圆周表面上的压敏胶带被电解液形成三维形状。因此，电极组件不会因外部振动或撞击而在罐内移动和旋转，并可防止标签焊接区域损坏或内部电路断开。