2-benzyloxy-3-bromopropionitrile | 118992-90-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzyloxy-3-bromopropionitrile
• 英文别名: 3-bromo-2-phenylmethoxypropanenitrile
• CAS: 118992-90-8
• 化学式: C₁₀H₁₀BrNO
• 分子量: 240.099
• InChiKey: QMCIGDNRTGOKPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  33
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  盐酸 、 2-benzyloxy-3-bromopropionitrile 、 2-benzyloxy-3-bromopropanamide 、 、 Methyl 2-benzyloxy-3-bromopropanoate 、 、 DBN potassium carbonate 在 ice 、 乙醚 、 水 、 碳酸氢钠 、 magnesium sulfate 、 crude product 、 methylene chloride diethyl ether 作用下， 以 甲醇 、 乙醚 、 正己烷 、 水 为溶剂， 反应 20.33h， 以to yield methyl α-benzyloxyacrylate, mp 44.5°-45.5° C. (from hexane)的产率得到methyl α-benzyloxyacrylate
  参考文献：
  名称：

  Control of molecular weight and end-group functionality of polymers

  摘要：

  一种通过自由基聚合生产聚合物的方法，其特征在于向聚合系统中添加一个或多个通式（A）的化合物。其中，R1是氢或能够激活乙烯基碳原子进行自由基加成的基团；Y是OR2或CH2X（R2）n，其中R2是可选择取代的烷基、烯基、炔基或饱和、不饱和或芳香的芳香环、碳环或杂环；X是周期表IV、V、VI或VII族中除碳以外的元素或一个由周期表IV、V或VI族元素和一个或多个氧原子组成的基团；n是0到3之间的数字，使得X基团的价被满足，当n大于1时，R2所代表的基团可以相同或不同。

  公开号：

  US05385996A1

文献信息

• Polymers of controlled molecular weight and end-group functionality
  申请人：E. I. du Pont de Nemours and Company

  公开号：US05874511A1

  公开（公告）日：1999-02-23

  A process for the production of polymers by free radical polymerization, characterized in that there is added to the polymerization system one or more compounds of the general formula (A). ##STR1## where R.sup.1 is hydrogen or a group capable of activating the vinylic carbon towards free radical addition; Y is OR.sup.2 or CH.sub.2 X(R.sup.2).sub.n where R.sup.2 is an optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, or optionally substituted saturated, unsaturated or aromatic carbocyclic or heterocyclic ring; X is an element other than carbon selected from Groups IV, V, VI or VII of the Periodic Table or a group consisting of an element selected from Groups IV, V, or VI to which is attached one or more oxygen atoms; and n is a number from 0 to 3, such that the valency of the group X is satisfied and, when n is greater than 1, the groups represented by R.sup.2 may be identical or different.

  通过自由基聚合生产聚合物的方法，其特征在于向聚合体系中添加一个或多个一般式（A）的化合物。其中，R1是氢或能够激活烯基碳原子向自由基加成的基团；Y是OR2或CH2X（R2）n，其中R2是可选取的取代基的烷基、烯基、炔基、饱和、不饱和或芳香碳环或杂环；X是周期表IV、V、VI或VII族中选择的碳之外的元素，或者是由周期表IV、V或VI族中选择的元素和一个或多个氧原子组成的基团；n是从0到3的数，使得基团X的价被满足，当n大于1时，由R2所代表的基团可以相同或不同。
• Free-radical chain transfer polymerization process
  申请人：Commonwealth Scientific and Industrial Research Organisation

  公开号：US05932675A1

  公开（公告）日：1999-08-03

  ##STR1## A process for the production of polymers by free radical polymerization, characterized in that there is added to the polymerization system one or more compounds of general formula (A), where R.sup.1 is a group capable of activating the vinylic carbon towards free radical addition; Y is CH.sub.2 X(R.sup.2).sub.n, where R.sup.2 is an optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, or optionally substituted saturated or unsaturated carbocyclic or heterocyclic ring; X is an element other than carbon selected from the Groups, IV, V, VI or VII of the Periodic Table or a group consisting of an element selected from the Groups IV, V, or VI to which is attached one or more oxygen atoms; and n is a number from 0 to 3, such that the valency of the group X is satisfied and, when n is greater than 1, the groups represented by R.sup.2 are identical or different.

  一种通过自由基聚合生产聚合物的工艺，其特征在于向聚合体系中添加一个或多个具有通式（A）的化合物，其中R.sup.1是能够激活乙烯基碳向自由基加成的基团; Y是CH.sub.2X（R.sup.2）.sub.n，其中R.sup.2是可选取代的烷基、可选取代的烯基、可选取代的炔基、或可选取代的饱和或不饱和碳环或杂环；X是周期表IV、V、VI或VII族中选择的除碳以外的元素，或者是一个由选择自IV、V或VI族的元素并附加一个或多个氧原子的基团组成；n是从0到3的数字，以满足基团X的价，当n大于1时，由R.sup.2所代表的基团是相同的或不同的。
• Process for producing polymers or oligomers of controlled molecular weight and end group functionalities
  申请人：Commonwealth Scientific & Industrial Resarch Organization

  公开号：US06197905B1

  公开（公告）日：2001-03-06

  A process for the production of polymers by free radical polymerization, characterized in that there is added to the polymerization system one or more compounds of general formula (A), where R1 is a group capable of activating the vinylic carbon towards free radical addition; Y is OR2, where R2 is an optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, or optionally substituted saturated or unsaturated carbocyclic or heterocyclic ring; X is an element other than carbon selected from the Groups, IV, V, VI or VII of the Periodic Table or a group consisting of an element selected from the Groups IV, V, or VI to which is attached one or more oxygen atoms; and n is a number from 0 to 3, such that the valency of the group X is satisfied and, when n is greater than 1, the groups represented by R2 are identical or different.

  一种通过自由基聚合生产聚合物的工艺，其特征在于向聚合体系中添加一个或多个通式（A）的化合物，其中R1是一个能够激活乙烯基碳原子向自由基加成的基团；Y为OR2，其中R2为可选择的取代基的烷基、烯基、炔基、或可选择的取代的饱和或不饱和碳环或杂环；X为周期表IV、V、VI或VII族中除碳以外的元素，或由周期表IV、V或VI族中的一个元素和一个或多个氧原子组成的基团；n为0到3的数字，使得X基团的价被满足，并且当n大于1时，由R2表示的基团是相同的或不同的。
• CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS
  申请人：COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION

  公开号：EP0333758B1

  公开（公告）日：1995-11-02
• EP0333758A4
  申请人：——

  公开号：EP0333758A4

  公开（公告）日：1990-05-14