2-[2-Hydroxy-4-(4-methylanilino)benzoyl]benzoic acid | 42803-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-Hydroxy-4-(4-methylanilino)benzoyl]benzoic acid
• CAS: 42803-75-8
• 化学式: C₂₁H₁₇NO₄
• 分子量: 347.4
• InChiKey: QPHARHZLYSVMDP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  86.6
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Purification process of keto acids
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP0853078A1

  公开（公告）日：1998-07-15

  A method for the purification of a keto acid having the general formula wherein R1 and R2 independently represent a straight or branched chain alkyl of 1-18 carbon atoms, a cycloalkyl of 4-8 carbon atoms or a phenyl both of which may be substituted by at least one substituent selected from the group consisting of halogen atoms and alkyls having 1-4 carbon atoms, an aralkyl of 7-10 carbon atoms, alkoxyalkyl having 2-20 carbon atoms, tetrahydrofuryl alkyl, alkylcarboxy alkyl, alkyl carboxy benzyl, or R1 and R2 together with the adjacent nitrogen atom may form a heterocyclic ring, or one of R 1 and R2 is hydrogen, which comprises slurrying the keto acid with an alcohol solvent, maintaining the slurry at elevated temperature in a sealed vessel until the Rhodamine impurity has dissolved, cooling and isolating the pure keto acid by filtration.

  一种具有通式的酮酸的提纯方法 其中 R1 和 R2 分别代表 1-18 个碳原子的直链或支链烷基、4-8 个碳原子的环烷基或苯基，二者均可被至少一个取代基取代，取代基可选自卤素原子和 1-4 个碳原子的烷基、7-10 个碳原子的芳烷基、2-20 个碳原子的烷氧基烷基、四氢糠基烷基、烷基羧基烷基、烷基羧基苄基组成的组、R1 和 R2 与相邻的氮原子一起可形成杂环，或者 R 1 和 R2 中的一个是氢，其中包括用醇溶剂将酮酸浆化，在密封容器中保持浆液高温，直到罗丹明杂质溶解，冷却并通过过滤分离出纯酮酸。
• PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1107972A1

  公开（公告）日：2001-06-20
• MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1115579A1

  公开（公告）日：2001-07-18
• US3931182A
  申请人：——

  公开号：US3931182A

  公开（公告）日：1976-01-06
• US3997541A
  申请人：——

  公开号：US3997541A

  公开（公告）日：1976-12-14