(24R,25S)-ergost-5-ene-3β,26-diol | 862499-01-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (24R,25S)-ergost-5-ene-3β,26-diol
• 英文别名: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R,6S)-7-hydroxy-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 862499-01-2
• 化学式: C₂₈H₄₈O₂
• 分子量: 416.688
• InChiKey: DUZMPSZAXXOQBT-OUKCADHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (24R,25S)-ergost-5-ene-3β,26-diol 在 吡啶 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 11.0h， 生成 菜油甾醇
  参考文献：
  名称：

  Taccasterosides A-C, Novel C28-Sterol Oligoglucosides from the Rhizomes of Tacca chantrieri

  摘要：

  研究人员从 Tacca chantrieri（Taccaceae）的根茎中分离出三种新型 C28-甾醇低聚葡萄糖苷，命名为 taccasterosides A-C（1-3）。通过详细的光谱分析（包括二维核磁共振数据）和一些化学转化，确定了它们的结构。

  DOI：

  10.1248/cpb.52.1396
• 作为产物：
  描述：

  (24R,25S)-26-{(β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)]-β-D-glucopyranosyl)oxy}ergost-5-en-3β-yl β-D-glucopyranoside 在 盐酸 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 1.0h， 以6.0 mg的产率得到(24R,25S)-ergost-5-ene-3β,26-diol
  参考文献：
  名称：

  New glycosides of the campesterol derivative from the rhizomes of Tacca chantrieri

  摘要：

  Seven new glycosides of the campesterol derivative (24R,25S)-ergost-5-ene-3 beta,26-diol (1-7) were isolated from the rhizomes of Tacca chantrieri (Taccaceae). Their structures were determined by extensive spectroscopic analysis, including 2D NMR data, and a few chemical transformations. (c) 2005 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.steroids.2004.11.006

文献信息

• Taccasterosides A-C, Novel C28-Sterol Oligoglucosides from the Rhizomes of Tacca chantrieri
  作者：Akihito Yokosuka、Yoshihiro Mimaki、Yutaka Sashida

  DOI：10.1248/cpb.52.1396

  日期：——

  Three novel C28-sterol oligoglucosides, named taccasterosides A—C (1—3), were isolated from the rhizomes of Tacca chantrieri (Taccaceae). Their structures were determined by detailed spectroscopic analysis, including 2D NMR data, and a few chemical transformations.

  研究人员从 Tacca chantrieri（Taccaceae）的根茎中分离出三种新型 C28-甾醇低聚葡萄糖苷，命名为 taccasterosides A-C（1-3）。通过详细的光谱分析（包括二维核磁共振数据）和一些化学转化，确定了它们的结构。
• New glycosides of the campesterol derivative from the rhizomes of Tacca chantrieri
  作者：Akihito Yokosuka、Yoshihiro Mimaki、Chiseko Sakuma、Yutaka Sashida

  DOI：10.1016/j.steroids.2004.11.006

  日期：2005.4

  Seven new glycosides of the campesterol derivative (24R,25S)-ergost-5-ene-3 beta,26-diol (1-7) were isolated from the rhizomes of Tacca chantrieri (Taccaceae). Their structures were determined by extensive spectroscopic analysis, including 2D NMR data, and a few chemical transformations. (c) 2005 Elsevier Inc. All rights reserved.