3-methoxy-4,4'-diisocyanatodiphenylmethane | 16832-64-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methoxy-4,4'-diisocyanatodiphenylmethane
• 英文别名: 1-Isocyanato-4-[(4-isocyanatophenyl)methyl]-2-methoxybenzene
• CAS: 16832-64-7
• 化学式: C₁₆H₁₂N₂O₃
• 分子量: 280.283
• InChiKey: QNPZPOKHLWDFBW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  68.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Interferon beta: remodeling and glycoconjugation of interferon beta
  申请人：Neose Technologies, Inc.

  公开号：US20040115168A1

  公开（公告）日：2004-06-17

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

  本发明包括重塑肽分子的方法和组合物，包括向肽添加或删除一个或多个糖基团，和/或向肽添加修饰基团。
• Glycoconjugation methods and proteins/peptides produced by the methods
  申请人：Neose Technologies, Inc.

  公开号：US20040142856A1

  公开（公告）日：2004-07-22

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

  本发明包括重塑肽分子的方法和组合物，包括向肽添加或删除一个或多个糖基团，和/或向肽添加修饰基团。
• Interleukin-2:remodeling and glycoconjugation of interleukin-2
  申请人：DeFrees Shawn

  公开号：US20050031584A1

  公开（公告）日：2005-02-10

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

  该发明包括重塑肽分子的方法和组合物，包括向肽分子中添加或删除一个或多个糖基团，和/或向肽分子中添加修饰基团。
• Protein remodeling methods and proteins/peptides produced by the methods
  申请人：Neose Technologies, Inc.

  公开号：US20040063911A1

  公开（公告）日：2004-04-01

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

  该发明涉及重塑肽分子的方法和组合物，包括向肽中添加或删除一个或多个糖基团，以及/或向肽中添加修饰基团。
• Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
  申请人：Neose Technologies, Inc.

  公开号：US20040077836A1

  公开（公告）日：2004-04-22

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

  本发明包括重塑肽分子的方法和组合物，包括向肽分子添加或删除一个或多个糖基团，和/或向肽分子添加修饰基团。