epoxycyclohexenol carboxamide | 1379366-12-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 乙烯酯类
• 英文名称: epoxycyclohexenol carboxamide
• 英文别名: 7-Oxabicyclo[4.1.0]hept-1-ene-2-carboxamide, 6-hydroxy-；6-hydroxy-7-oxabicyclo[4.1.0]hept-1-ene-2-carboxamide
• CAS: 1379366-12-7
• 化学式: C₇H₉NO₃
• 分子量: 155.153
• InChiKey: BBFQRGBQXQKVSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  75.8
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• US6448443B1
  申请人：——

  公开号：US6448443B1

  公开（公告）日：2002-09-10
• US7109377B2
  申请人：——

  公开号：US7109377B2

  公开（公告）日：2006-09-19
• [EN] SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS<br/>[FR] SYNTHESE COMBINATOIRE D'ECHANTILLOTHEQUES DE COMPOSES REMINISCENTS DE PRODUITS NATURELS
  申请人：HARVARD COLLEGE

  公开号：WO2000006525A2

  公开（公告）日：2000-02-10

  The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.