((5,6),(5',6')-Bis(methylenedioxy)biphenyl-2,2'-diyl)bis(bis (cyclohexyl)phosphine) | 210169-52-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: ((5,6),(5',6')-Bis(methylenedioxy)biphenyl-2,2'-diyl)bis(bis (cyclohexyl)phosphine)
• 英文别名: [(5,6),(5',6')-bis(methylenedioxy)biphenyl-2,2'-diyl]bis(dicyclohexylphosphine)；((4,4'-bi-1,3-benzodioxole)-5,5'-diyl)bis(dicyclohexylphosphine)；(+)-5,5'-Bis(dicyclohexylphosphino)-4,4'-bibenzo[d][1,3]dioxole；dicyclohexyl-[4-(5-dicyclohexylphosphanyl-1,3-benzodioxol-4-yl)-1,3-benzodioxol-5-yl]phosphane
• CAS: 210169-52-1
• 化学式: C₃₈H₅₂O₄P₂
• 分子量: 634.776
• InChiKey: FVDQWAKAOJAYBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.6
• 重原子数：
  44
• 可旋转键数：
  7
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Axially Asymmetric Phosphorus Compound and Production Method Thereof
  申请人：Tanaka Ken

  公开号：US20090227805A1

  公开（公告）日：2009-09-10

  Problem to be Solved: To provide an axially asymmetric optically active biarylphosphorus compound that can easily produced without the step of optical resolution which was almost indispensable in conventional methods. Solution: A method for producing an axially asymmetric phosphorus compound represented by the general formula (1), comprising a cycloaddition reaction of a compound having a triple bond with the use of a catalyst containing rhodium metal and an optically active bisphosphine. (In the formula, J is an oxygen atom, a sulfur atom or BH 3 ; R 1 and R 2 independently are an alkyl, cycloalkyl, aryl, alkoxy and aryloxy group; a1 and a2 independently are 0 or 1; R 3 to R 10 independently are an alkyl, cycloalkyl, aryl, alkoxy and aryloxy group; two among R 3 to R 10 may form a ring; and * is axial asymmetry.)

  要解决的问题：提供一种轴向不对称的光学活性联苯磷化合物，可以在传统方法中几乎不可或缺的光学分辨步骤之外轻松生产。 解决方案：一种生产由通式（1）表示的轴向不对称磷化合物的方法，包括使用含有铑金属和光学活性双膦的催化剂进行含有三键化合物的环加成反应。 （在公式中，J是氧原子、硫原子或BH3；R1和R2独立地是烷基、环烷基、芳基、烷氧基和芳氧基；a1和a2独立地为0或1；R3到R10独立地是烷基、环烷基、芳基、烷氧基和芳氧基；R3到R10中的两个可能形成环；*表示轴向不对称。）
• METHOD FOR PREVENTING DECREASE IN OPTICAL PURITY
  申请人：Nara Hideki

  公开号：US20140296582A1

  公开（公告）日：2014-10-02

  The present invention provides a method for producing a reduction reaction product, wherein recovery of the reaction solvent and/or distillation is carried out after adding a nitrogen-containing compound into a reaction liquid of a reduction reaction that has been conducted using a transition metal complex. The present invention is capable of suppressing decrease in the optical purity of the reduction reaction product due to the transition metal complex used as a catalyst.

  本发明提供了一种生产还原反应产物的方法，其中在向使用过渡金属配合物进行的还原反应的反应液中添加含氮化合物后，进行反应溶剂和/或蒸馏的回收。本发明能够抑制由于作为催化剂使用的过渡金属配合物导致的还原反应产物光学纯度降低。
• PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINE
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20150210657A1

  公开（公告）日：2015-07-30

  A process for producing an optically active amine compound, characterized by asymmetrically hydrogenating a prochiral carbon-nitrogen double bond in the presence of a ruthenium complex represented by general formula (1) or (2) (wherein P represents an optically active diphosphine, X represents an anionic group, and Ar represents an optionally substituted arylene group).

  一种制备光学活性胺化合物的方法，其特征在于在存在由通用式（1）或（2）表示的钌配合物的情况下，对一个丙半胱氨基双键进行不对称氢化（其中P代表光学活性二膦，X代表阴离子基团，Ar代表可选择取代的芳基基团）。
• Axially asymmetric ester compound and production method thereof
  申请人：Tanaka Ken

  公开号：US20090299076A1

  公开（公告）日：2009-12-03

  To provide an axially asymmetric optically active biaryl ester compound that can easily produced without the step of optical resolution which was almost indispensable in conventional methods. There is provided a method for producing an axially asymmetric ester compound, comprising a cycloaddition of a compound having a triple bond with the use of a catalyst containing rhodium metal and an optically active bisphosphine.

  提供一种具有轴向不对称光学活性的双芳基酯化合物，可在传统方法中几乎不可或缺的光学分辨步骤之外轻松生产。提供了一种生产轴向不对称酯化合物的方法，包括使用含有铑金属和光学活性双膦催化剂对具有三键的化合物进行环加成。
• Process for producing an alcohol or a silyl ether thereof
  申请人：Shibasaki Masakatsu

  公开号：US20060199973A1

  公开（公告）日：2006-09-07

  A process for producing an alcohol or a silyl ether thereof of formula (4): wherein R 1 represents a hydrocarbon, a heterocyclic, or an alkoxycarbonyl group; R 2 represents hydrogen or CO 2 R; X represents an aryl or an alkenyl group of formula (3): and R 8 represents hydrogen or a silyl residue, by reacting a compound R 1 (C═O)R 2 with a silane (R 3 ) 2 R 4 Si—X, wherein R 3 and R 4 each represents an alkyl, an alkoxy, or an aryl group; in the presence of (i) a catalyst component containing copper fluoride or a catalyst component containing a copper compound and a fluoride and (ii) a bidentate phosphine compound or in the presence of a complex obtained from the foregoing components.

  生产醇或其硅基醚的方法，其分子式为（4）：其中R1代表烃基、杂环基或烷氧羰基；R2代表氢或CO2R；X代表分子式（3）的芳基或烯基；R8代表氢或硅基残基，通过将化合物R1(C═O)R2与硅烷（R3）2R4Si—X反应，其中R3和R4分别代表烷基、烷氧基或芳基，在（i）含有氟化铜的催化剂组分或含有铜化合物和氟化物的催化剂组分和（ii）双齿膦化合物的存在下，或在从上述组分得到的络合物的存在下。