N-Benzyl-1-nitrosomethanamine | 53459-97-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-Benzyl-1-nitrosomethanamine
• 英文别名: N-(nitrosomethyl)-1-phenylmethanamine
• CAS: 53459-97-5
• 化学式: C₈H₁₀N₂O
• 分子量: 150.18
• InChiKey: JLIRCCVGMUDWOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Sulfur containing compounds
  申请人：——

  公开号：US20030220524A1

  公开（公告）日：2003-11-27

  This invention is directed to novel and known stufur containing compounds and pharmaceutically acceptable salts thereof that have utility as antifungals and as antiproliferative agents against mammalian cells, in particular cancer cells and most particularly leukemia-derived cells. The invention provides a method for synthesizing certain of the sulfur containing compounds that is more efficient than previously known methods.

  这项发明涉及新颖且已知的含有硫的化合物以及具有抗真菌活性和作为哺乳动物细胞，特别是癌细胞，尤其是白血病来源细胞的抗增殖剂的药用可接受盐。发明提供了一种合成某些含硫化合物的方法，该方法比先前已知的方法更有效。
• [EN] BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER<br/>[FR] COMPOSITIONS D'ACIDE BORONIQUE ET PROCÉDÉS SE RAPPORTANT AU CANCER
  申请人：UNIV GEORGETOWN

  公开号：WO2011022502A1

  公开（公告）日：2011-02-24

  Disclosed are compounds and methods related to boronic acid derivatives of resveratrol. Certain of these derivatives have enhanced efficacy relative to resveratrol, function as irreversible modulators, and act at the Gl/S phase of the cell cycle.

  本发明涉及白藜芦醇的硼酸衍生物化合物和方法。其中某些衍生物相对于白藜芦醇具有增强的功效，作为不可逆调节剂，并在细胞周期的G1/S期发挥作用。
• BORONIC ACID COMPOSITIONS AND METHODS RELATED TO CANCER
  申请人：Brown Milton L.

  公开号：US20120149663A1

  公开（公告）日：2012-06-14

  Disclosed are compounds and methods related to boronic acid derivatives of resveratrol. Certain of these derivatives have enhanced efficacy relative to resveratrol, function as irreversible modulators, and act at the GI/S phase of the cell cycle.

  本发明涉及白藜芦醇的硼酸衍生物化合物和方法。其中某些衍生物具有相对于白藜芦醇增强的功效，作为不可逆调节因子，并在细胞周期的GI/S阶段起作用。
• PREVENTION AND TREATMENT OF COLON CANCER
  申请人：Rimando Agnes M.

  公开号：US20120178704A1

  公开（公告）日：2012-07-12

  Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.

  提供了用于预防和治疗结肠癌或结肠炎的双苯乙烯化合物及其使用方法。
• Anion exchange resins having controlled nitrosamine formation
  申请人：Dow Global Technologies LLC

  公开号：EP2471598A1

  公开（公告）日：2012-07-04

  An anion exchange resin produced comprising providing an anion exchange resin with a nitrosating agent and applying an antioxidant to the resin to inhibit formation of nitrosamines on the anion exchange resin.

  一种阴离子交换树脂的生产工艺，包括在阴离子交换树脂中加入亚硝酸化剂，并在树脂中加入抗氧化剂，以抑制亚硝胺在阴离子交换树脂上的形成。