[4-(三苯基甲基)苯氧基]乙酸 | 162456-86-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: [4-(三苯基甲基)苯氧基]乙酸
• 英文名称: [4-(triphenylmethyl)phenoxy]acetic acid
• 英文别名: 2-(4-tritylphenoxy)acetic acid；4-tritylphenoxyacetic acid；(4-Tritylphenoxy)acetic acid
• CAS: 162456-86-2
• 化学式: C₂₇H₂₂O₃
• 分子量: 394.47
• InChiKey: WZLHZWZKPYCHPX-UHFFFAOYSA-N

物化性质

• 沸点：
  544.6±38.0 °C(Predicted)
• 密度：
  1.191±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [4-(三苯基甲基)苯氧基]乙酸 在 4-二甲氨基吡啶 、 sodium hydroxide 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 四氢呋喃 、 乙醇 、 二氯甲烷 为溶剂， 反应 24.0h， 生成 2-(2-(2-(4-tritylphenoxy)acetamido)acetamido)acetic acid
  参考文献：
  名称：

  Photoisomerization of Spiropyran for Driving a Molecular Shuttle

  摘要：

  A novel light-powered molecular shuttle was synthesized which can switch the movement of a macrocycle between two distinct stations-dipeptide and zwitterionic ME-by exploiting the photoisomerization of spiropyran. The macrocycle resides selectively in the dipeptide station in the SP form and moves to the ME station under the irradiation of UV light. This movement process of the macrocycle is accompanied by reversible absorptive output signals which can be detected by the naked eye.

  DOI：

  10.1021/ol7015862
• 作为产物：
  描述：

  2-(4-tritylphenoxy)acetic acid ethyl ester 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 10.0h， 以2.1 g的产率得到[4-(三苯基甲基)苯氧基]乙酸
  参考文献：
  名称：

  Photoisomerization of Spiropyran for Driving a Molecular Shuttle

  摘要：

  A novel light-powered molecular shuttle was synthesized which can switch the movement of a macrocycle between two distinct stations-dipeptide and zwitterionic ME-by exploiting the photoisomerization of spiropyran. The macrocycle resides selectively in the dipeptide station in the SP form and moves to the ME station under the irradiation of UV light. This movement process of the macrocycle is accompanied by reversible absorptive output signals which can be detected by the naked eye.

  DOI：

  10.1021/ol7015862

文献信息

• High-Yielding Cleavage of (Aryloxy)acetates
  作者：Anke Spurg、Siegfried R. Waldvogel

  DOI：10.1002/ejoc.200700769

  日期：2008.1

  A reliable and high-yielding one-pot sequence for the removal of O-carboxymethyl moieties from phenols is presented. When diethylphosphoryl azide is employed as theazide transfer reagent in the Curtius rearrangement and glycerol in the subsequent hydrolytic workup, the protocol can be reliably applied to a very broad scope of substrates. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany

  提出了一种用于从酚中去除 O-羧甲基部分的可靠且高产的一锅法序列。当二乙基磷酰叠氮化物用作 Curtius 重排中的叠氮化物转移试剂和随后的水解处理中的甘油时，该协议可以可靠地应用于非常广泛的底物。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
• A photoswitchable rotaxane operating in monolayers on solid support
  作者：Felix B. Schwarz、Thomas Heinrich、Andreas Lippitz、Wolfgang E. S. Unger、Christoph A. Schalley

  DOI：10.1039/c6cc08586e

  日期：——

  A novel photoswitchable rotaxane was synthesised and its switching behaviour in solution was analysed with NMR and UV-VIS. A monolayer of rotaxanes was deposited on glass surfaces and the on-surface...

  合成了一种新型的光开关轮烷，并用NMR和UV-VIS分析了其在溶液中的开关行为。轮烷的单层沉积在玻璃表面上，其表面...
• Synthesis and properties of [4-(triphenylmethyl)phenoxy]acetic and 3-[4-(triphenylmethyl)phenoxy]propionic acids and their condensation with phthalimide leading to meso-substituted tetrabenzoporphyrins
  作者：N. E. Galanin、L. A. Yakubov、G. P. Shaposhnikov

  DOI：10.1134/s1070428009070070

  日期：2009.7

  Condensation of 4-(triphenylmethyl)phenol with monochloroacetic and 3-bromopropionic acids gave, respectively, [4-(triphenylmethyl)phenoxy]acetic and 3-[4-(triphenylmethyl)phenoxy]propionic acids which reacted with phthalimide in the presence of zinc acetate to produce meso-substituted zinc tetrabenzoporphyrins having bulky triphenylmethyl groups in the substituent. The corresponding free ligands were

  4-（三苯甲基）苯酚与一氯乙酸和3-溴丙酸的缩合分别得到[4-（三苯甲基）苯氧基]乙酸和3- [4-（三苯甲基）苯氧基]丙酸，它们在锌的存在下与邻苯二甲酰亚胺反应乙酸酯生产具有在取代基中具有庞大的三苯甲基基团的内消旋取代的四苯并卟啉锌。通过使锌络合物脱金属获得相应的游离配体。研究了合成化合物的光谱性质。
• Jullien, Ludovic; Canceill, Josette; Lacombe, Liliane, Journal of the Chemical Society. Perkin transactions II, 1994, # 5, p. 989 - 1002
  作者：Jullien, Ludovic、Canceill, Josette、Lacombe, Liliane、Lehn, Jean-Marie

  DOI：——

  日期：——
• Charge Transfer Chromophore-Stopped [2]Rotaxane through [2 + 2] Cycloaddition
  作者：Weidong Zhou、Jialiang Xu、Haiyan Zheng、Huibiao Liu、Yuliang Li、Daoben Zhu

  DOI：10.1021/jo8014566

  日期：2008.10.3

  Three charge-transfer chromophore-terminated [2]rotaxanes were synthesized, using a high-yield [2 + 2]cycloaddition reaction in apolar solvent at room temperature. Two solvent-driving molecular shuttles were constructed, which exhibit distinct conformations in different solvent as a result of the shuttling movement of the macrocycle.