(6-ethyl-3-pyridyl)methyl azide | 474555-14-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (6-ethyl-3-pyridyl)methyl azide
• 英文别名: 5-(azidomethyl)-2-ethylpyridine
• CAS: 474555-14-1
• 化学式: C₈H₁₀N₄
• 分子量: 162.194
• InChiKey: MHWPNNFEZHEELY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  27.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (6-ethyl-3-pyridyl)methyl azide 在 过氧化氢苯甲酰 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 以87.6%的产率得到5-(azidomethyl)-2-ethyl-1-pyridiniumolate
  参考文献：
  名称：

  2-IMINOPYRROLIDINE DERIVATES

  摘要：

  公开号：

  EP1391451B1
• 作为产物：
  描述：

  (6-ethyl-3-pyridyl)methanol 在 叠氮磷酸二苯酯 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 甲苯 为溶剂， 反应 18.0h， 以84.5%的产率得到(6-ethyl-3-pyridyl)methyl azide
  参考文献：
  名称：

  2-IMINOPYRROLIDINE DERIVATES

  摘要：

  公开号：

  EP1391451B1

文献信息

• 2-Iminopyrrolidine derivatives
  申请人：Suzuki Shuichi

  公开号：US20050245592A1

  公开（公告）日：2005-11-03

  A 2-iminopyrrolidine derivative represented by the formula: wherein ring B represents a benzene ring, pyridine ring, etc.; R 101 -R 103 represent hydrogen, halogen, C 1-6 alkyl, etc.; R 5 represents hydrogen, C 1-6 alkyl, C 1-6 alkoxy-C 1-6 alkyl, etc.; R 6 represents hydrogen, C 1-6 alkyl, C 1-6 alkyloxycarbonyl, etc.; Y 1 represents a single bond, —CH 2 —, etc.; Y 2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R 10 -R 14 represent hydrogen, C 1-6 alkyl, hydroxyl, C 1-6 alkoxy, etc.; and R 11 and R 12 or R 12 and R 13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.

  一种2-伊米诺吡咯烷衍生物，其化学式为：其中环B代表苯环、吡啶环等；R101-R103代表氢、卤素、C1-6烷基等；R5代表氢、C1-6烷基、C1-6烷氧基-C1-6烷基等；R6代表氢、C1-6烷基、C1-6烷氧羰基等；Y1代表单键，-CH2-等；Y2代表单键，-CO-等；Ar代表氢，一个由以下式子表示的基团：[其中R10-R14代表氢、C1-6烷基、羟基、C1-6烷氧基等；R11和R12或R12和R13可以结合形成5-至8-成员的杂环]，等，或其盐。
• 2-iminopyrrolidine derivatives
  申请人：Eisai Co., Ltd

  公开号：US07244730B2

  公开（公告）日：2007-07-17

  A 2-iminopyrrolidine derivative represented by the formula: wherein ring B represents a benzene ring, pyridine ring, etc.; R101–R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.

  一种由以下式子表示的2-伊米诺吡咯烷衍生物：其中环B代表苯环、吡啶环等；R101-R103代表氢、卤素、C1-6烷基等；R5代表氢、C1-6烷基、C1-6烷氧基-C1-6烷基等；R6代表氢、C1-6烷基、C1-6烷氧羰基等；Y1代表单键、—CH2—等；Y2代表单键、—CO—等；Ar代表氢、由以下式子表示的基团：[其中R10-R14代表氢、C1-6烷基、羟基、C1-6烷氧基等；且R11和R12或R12和R13可以结合形成5-至8-成员的杂环]等。}或其盐。
• Hair cosmetic composition
  申请人：KAO CORPORATION

  公开号：EP1568350A2

  公开（公告）日：2005-08-31

  Provided is a leave-on hair cosmetic composition, which contains the following components (A), (B) and (C): (A) an organic C2-8 dicarboxylic acid or salt thereof, (B) at least one or more of an organic solvent selected from the group consisting of aromatic alcohols, N-alkylpyrrolidones, alkylene carbonates, polypropylene glycols, lactones and cyclic ketones, wherein the organic solvent has a ClogP of from -2 to 3, and (C) at least one or more of a compound selected from the group consisting of benzophenones, para-aminobenzoic acids, para-methoxycinnamic acids, salicylic acids, rutin and 4-tert-butyl-4'-methoxybenzoylmethane; wherein the cosmetic composition has a pH of from 2 to 5 at 25°C when diluted to 20 times the weight with water. The present invention also relates to a hair quality improving method which includes treating the hair with the hair cosmetic composition. The hair cosmetic composition of the present invention can provide benefits such as luster, manageability, pliability and elasticity to the hair which is apt to be dry, having lost water therefrom owing to damage by coloring, permanent weaving, or repetitive excessive blow drying.

  本发明提供了一种免洗护发化妆品组合物，它包含以下成分（A）、（B）和（C）： (A) 有机 C2-8 二羧酸或其盐、 (B) 至少一种或多种有机溶剂，选自由芳香醇、N-烷基吡咯烷酮、碳酸亚烷基酯、聚丙二醇、内酯和环酮组成的组，其中有机溶剂的 ClogP 值为-2 至 3，以及 (C) 至少一种或多种选自二苯甲酮类、对氨基苯甲酸类、对甲氧基肉桂酸类、水杨酸类、芦丁和 4-叔丁基-4'-甲氧基苯甲酰甲烷的化合物； 其中，当用水稀释至 20 倍重量时，化妆品组合物在 25°C 时的 pH 值为 2 至 5。本发明还涉及一种改善发质的方法，该方法包括用头发化妆品组合物处理头发。 本发明的头发化妆品组合物可为因染发、永久性编织或反复过度吹干而失水的头发提供光泽、易于打理、柔顺和富有弹性等益处。
• ULTRAVIOLET PROTECTIVE PREPARATION AND COSMETICS CONTAINING THE SAME
  申请人：The Nisshin OilliO Group, Ltd.

  公开号：EP1671617A1

  公开（公告）日：2006-06-21

  An ultraviolet protective preparation comprising an ester prepared from glycerol and/or a condensate thereof, a straight-chain saturated fatty acid having 2 to 28 carbon atoms, and an aliphatic saturated dibasic acid having 12 to 28 carbon atoms, an oil liquid or pasty at ordinary temperatures which consists of an ester of a mono- to hexa-carboxylic acid having 2 to 36 carbon atoms with a mono- to hexa-hydric alcohol having 1 to 36 carbon atoms, and an ultraviolet protective powder in prescribed portions; and cosmetics containing the ultraviolet protective preparation. The invention provides an ultraviolet protective preparation which is improved in the dispersion stability of ultraviolet protective powder such as titanium dioxide or zinc oxide while keeping the handleability and the ability to give cosmetics excellent in organoleptic properties and storage stability; and cosmetics excellent in organoleptic properties and storage stability.

  一种紫外线防护制剂，包括由甘油和/或其缩合物、具有 2 至 28 个碳原子的直链饱和脂肪酸和具有 12 至 28 个碳原子的脂肪族饱和二元酸制备的酯、在常温下由具有 2 至 36 个碳原子的一元至六元羧酸与具有 1 至 36 个碳原子的一元至六元醇的酯组成的油状液体或糊状物，以及规定份量的紫外线防护粉末；以及含有该紫外线防护制剂的化妆品。本发明提供了一种紫外线防护制剂，它提高了二氧化钛或氧化锌等紫外线防护粉末的分散稳定性，同时保持了可操作性，能够使化妆品具有优异的感官特性和储存稳定性；以及具有优异的感官特性和储存稳定性的化妆品。
• COSMETIC METHOD FOR SMOOTHING WRINKLES AND FINE LINES USING AN INTERPOLYMER
  申请人：Chanel Parfums Beauté

  公开号：EP2259765B1

  公开（公告）日：2012-08-15