5-(2-Hydroxyethyl)dihydropyrimidine-2,4(1H,3H)-dione | 828241-25-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-(2-Hydroxyethyl)dihydropyrimidine-2,4(1H,3H)-dione
• 英文别名: 5-(2-hydroxyethyl)-1,3-diazinane-2,4-dione
• CAS: 828241-25-4
• 化学式: C₆H₁₀N₂O₃
• 分子量: 158.16
• InChiKey: FAPGLIUAYDSVAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  78.4
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Method for time-dependent decrease of ph in a cosmetic composition and a composition for permanent hair shaping with time-dependent decrease of the wave-shaping efficiency
  申请人：Wella Aktiengesellschaft

  公开号：EP1500386A1

  公开（公告）日：2005-01-26

  A method for time dependent decrease of pH in a cosmetic composition for treating skin or hair, preferably a method for permanently shaping hair, for which, immediately before use, an enzyme that catalyzes an acid-generating reaction with a non-ester substrate to form a ready-to-apply cosmetic composition is added immediately (preferably 5 seconds to 3 minutes) prior to use to an alkaline composition having an initial pH of 7.0 to 14 and comprising a non-ester substrate,. Than the hair, before and/or after it is held in the desired shape, is treated with the ready-to-use agent and, after the period of action, is rinsed with water. Thereafter the hair is treated oxidatively, rinsed again with water, optionally laid into a water wave and then dried. Preferably the enzyme and the non-ester substrate is selected so that the initial pH of 7.0 to 12 is lowered within a time interval of from 5 to 40 minutes by at least 0.5 pH units.

  一种使用于治疗皮肤或头发的化妆品组合物中的 pH 值随时间变化而降低的方法，最好是一种使头发永久定型的方法，为此，在使用前，立即（最好是 5 秒至 3 分钟）向初始 pH 值为 7.0 至 14 且包含非酯类底物的碱性组合物中加入一种酶，该酶可催化与非酯类底物的酸生成反应，从而形成一种即用型化妆品组合物。然后，在头发保持所需的形状之前和/或之后，用即用型药剂处理头发，并在作用期结束后用水冲洗。然后对头发进行氧化处理，再次用水冲洗，可选择将头发铺成水波状，然后烘干。最好选择酶和非酯类底物，以便在 5 至 40 分钟的时间间隔内将 7.0 至 12 的初始 pH 值降低至少 0.5 个 pH 单位。