(3S,6R,7R)-3,7,11-trimethyl-3,6-epoxy-1,10-dodecadien-7-ol | 72523-47-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: (3S,6R,7R)-3,7,11-trimethyl-3,6-epoxy-1,10-dodecadien-7-ol
• 英文别名: (3s,6r,7r)-3,7,11-Trimethyl-3,6-epoxy-1,10-dodecadien-7-ol；(2R)-2-[(2R,5S)-5-ethenyl-5-methyloxolan-2-yl]-6-methylhept-5-en-2-ol
• CAS: 72523-47-8
• 化学式: C₁₅H₂₆O₂
• 分子量: 238.37
• InChiKey: OIVTVPOJCWXSIC-RBSFLKMASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (3S,6R,7R)-3,7,11-trimethyl-3,6-epoxy-1,10-dodecadien-7-ol 、 (S)-(-)-α-甲氧基-α-(三氟甲基)苯乙酸 以 氘代吡啶 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  Bioactive sesquiterpenes isolated from the essential oil of Dalbergia odorifera T. Chen

  摘要：

  Investigation of the essential oil from the heartwood of Dalbergia odorifera T. Chen afforded the sesquiterpenes 1 and 2, that both showed anti-platelet activity. Their backbones were totally the same only with subtle difference in the chiral centre. Additionally, antithrombotic and antiplatelet activities of these two compounds were measured. The results showed that the antithrombotic activity of these two compounds was poor, while their anti-platelet activity was strong at middle and high concentrations. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.fitote.2009.11.012

文献信息

• Bioactive sesquiterpenes isolated from the essential oil of Dalbergia odorifera T. Chen
  作者：Yi Tao、Yi Wang

  DOI：10.1016/j.fitote.2009.11.012

  日期：2010.7

  Investigation of the essential oil from the heartwood of Dalbergia odorifera T. Chen afforded the sesquiterpenes 1 and 2, that both showed anti-platelet activity. Their backbones were totally the same only with subtle difference in the chiral centre. Additionally, antithrombotic and antiplatelet activities of these two compounds were measured. The results showed that the antithrombotic activity of these two compounds was poor, while their anti-platelet activity was strong at middle and high concentrations. (C) 2009 Elsevier B.V. All rights reserved.