6-Methyl-4,5-dihydro-3H-pyridin-2-one | 24058-29-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-Methyl-4,5-dihydro-3H-pyridin-2-one
• 英文别名: 6-Methyl-4,5-dihydropyridin-2(3H)-one
• CAS: 24058-29-5
• 化学式: C₆H₉NO
• 分子量: 111.144
• InChiKey: UBQYMDOSRRHSSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests
  申请人：Clark David Alan

  公开号：US20080132524A1

  公开（公告）日：2008-06-05

  This invention pertains to compounds of Formula I, their N-oxides and suitable salts wherein A is O or S; G is a 5- or 6-membered heteroaromatic ring or a 5- or 6-membered nonaromatic heterocyclic ring optionally including one or two ring members selected from the group consisting of C(═O), SO or S(O) 2 , each ring optionally substituted with from one to four R 2 ; each J is independently a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system, wherein each ring or ring system is optionally substituted with from one to four R 3 ; and R 1 , R 2 , R 3 , R 4 and n are as defined in the disclosure. A composition comprising a compound of Formula I, and a method for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula I are also disclosed.

  本发明涉及式I的化合物、它们的N-氧化物和适当的盐，其中A为O或S；G为5-或6-成员杂芳环或5-或6-成员非芳杂环，可选地包括来自C(═O)、SO或S(O)2的一个或两个环成员，每个环可选地用1至4个R2取代；每个J独立地为苯环、5-或6-成员杂芳环或芳香8-、9-或10-成员融合的碳双环或杂双环系统，其中每个环或环系统可选地用1至4个R3取代；而R1、R2、R3、R4和n如说明书所定义。本发明还揭示了一种包含式I化合物的组合物，以及一种控制无脊椎动物害虫的方法，包括与式I化合物的生物有效量接触无脊椎动物害虫或其环境。
• Novel cycloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists
  申请人：Wehner Volkmar

  公开号：US20080021055A1

  公开（公告）日：2008-01-24

  There are described cycloalkyl derivatives of the formula (I) R 1 —Y-A-B-D-E-F-G   (I) in which R 1 , Y, A, B, D, E, F and G have the meaning indicated herein, their preparation and their use as medicaments. The compounds according to the invention can be used as vitronectin receptor antagonists and as inhibitors of bone resorption.

  本文描述了公式（I）的环烷基衍生物R1-Y-A-B-D-E-F-G，其中R1，Y，A，B，D，E，F和G的含义如下所示，以及它们的制备方法和作为药物的用途。根据本发明的化合物可以用作vitronectin受体拮抗剂和骨吸收抑制剂。
• US7348333B2
  申请人：——

  公开号：US7348333B2

  公开（公告）日：2008-03-25
• US7375232B2
  申请人：——

  公开号：US7375232B2

  公开（公告）日：2008-05-20
• US7629463B2
  申请人：——

  公开号：US7629463B2

  公开（公告）日：2009-12-08