Synthesis and biological activity of 2-hydroxyalkylammonium salts of [organothio]acetic acids
作者:G. G. Levkovskaya、Yu. I. Kryukova、É. É. Kuznetsova、G. S. Dolgushina、T. A. Pushechkina、S. K. Suslova、T. I. Malkova、M. G. Voronkov、A. N. Mirskova
DOI:10.1007/bf01150721
日期:1983.6
of the type ArOC(RtR2)COOR and their derivatives are used in agriculture as herbicides and plant-growth stimulators [I], and in medicine as hypocholesterolemic, hypolipidemic, and antiarrhythmic agents [2, 3]; they also exhibit antitumor activity [4]. The biological properties of their sulfur analogs -the (organothio)alkanecarboxylic acids and their derivatives, which contain four and six-valent sulfur
ArOC(RtR2)COOR 型芳氧基烷烃羧酸及其衍生物在农业中用作除草剂和植物生长刺激剂 [I],在医药中用作降胆固醇、降血脂和抗心律失常剂 [2, 3];它们还表现出抗肿瘤活性 [4]。它们的硫类似物——含有四价和六价硫的(有机硫代)烷烃羧酸及其衍生物——的生物学特性尚未得到广泛研究。已经报道了芳硫基和芳基磺酰乙酸的生长刺激活性 [5, 6],以及 AlkC6H4CH(SR)COOH 类型的有机硫代取代酸及其酯 [7] 的抗炎和镇痛活性。通式RC(RIR2)COOH的化合物,其中R是未取代或取代的噻吩基-2基团,