sodium 4-carboxymethylthio-2,5-dichlorobenzenesulfonate | 143851-35-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: sodium 4-carboxymethylthio-2,5-dichlorobenzenesulfonate
• 英文别名: Sodium;4-(carboxymethylsulfanyl)-2,5-dichlorobenzenesulfonate
• CAS: 143851-35-8
• 化学式: C₈H₅Cl₂O₅S₂*Na
• 分子量: 339.152
• InChiKey: BGSMNPRTJCIFAH-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.92
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  128
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  sodium 4-carboxymethylthio-2,5-dichlorobenzenesulfonate 在 硫酸 作用下， 生成 2,5-Dichlorophenylmercaptoacetic acid
  参考文献：
  名称：

  2,5-dichlorophenylthioglycolic acid derivative and method for its

  摘要：

  本发明涉及一种新型2,5-二氯苯硫代乙酸衍生物，其制备方法以及从所述新化合物中得到所需产物2,5-二氯苯硫代乙酸的方法。本发明的2,5-二氯苯硫代乙酸衍生物可通过在碱的存在下反应2,4,5-三氯苯磺酸盐和硫代乙酸来获得，所述所需产物可通过在矿酸水溶液中脱磺化所述化合物来获得。本发明的新型4-羧甲基硫基-2,5-二氯苯磺酸盐可以优势地用作生产2,5-二氯苯硫代乙酸的中间体。使用该中间体可以在减少的工艺步骤中高产率地获得所需产物。此外，它不像传统方法那样存在环境污染问题，因为它不使用重金属。

  公开号：

  US05210287A1

文献信息

• 2,5-dichlorophenylthioglycolic acid derivative and method for its production
  申请人：SUMITOMO SEIKA CHEMICALS CO., LTD.

  公开号：EP0496396A2

  公开（公告）日：1992-07-29

  The present invention is directed to novel 2,5-dichlorophenylthioglycolic acid derivative, a process for their production and a process for producing the desired product 2,5-dichlorophenylthioglycolic acid derived from said novel compounds. 2,5-dichlorophenylthioglycolic acid derivative of the present invention can be obtained by reacting 2,4,5-trichlorobenzensulfonates and thioglycolic acid in the presence of base, and said desired product can be obtained by desulfonating said compound in an aqueous solution of mineral acid. Novel 4-carboxymethylthio-2,5-dichlorobenzenesulfonates of the present invention can be used advantageously as an intermediate for the production of 2,5-dichlorophenylthioglycolic acid. The use of said intermediate makes it possible to obtain the desired product in a decreased process steps with high yield. In addition, it poses no problem of environmental pollution as pointed out with conventional methods because it uses no heavy metals.

  本发明涉及新型 2,5-二氯苯基硫代乙醇酸衍生物、其生产工艺以及由所述新型化合物衍生的所需产品 2,5-二氯苯基硫代乙醇酸的生产工艺。本发明的 2,5-二氯苯基硫代乙醇酸衍生物可通过 2,4,5-三氯苯磺酸盐和硫代乙醇酸在碱存在下发生反应而获得，通过在矿物酸水溶液中对所述化合物进行脱硫处理可获得所述所需产品。本发明的新型 4-羧甲基硫代-2,5-二氯苯磺酸盐可用作生产 2,5-二氯苯基硫代乙醇酸的中间体，具有优势。使用上述中间体可以减少工艺步骤，获得高产率的所需产品。此外，由于不使用重金属，它不会像传统方法那样造成环境污染问题。
• US5210287A
  申请人：——

  公开号：US5210287A

  公开（公告）日：1993-05-11
• US5352821A
  申请人：——

  公开号：US5352821A

  公开（公告）日：1994-10-04
• 2,5-dichlorophenylthioglycolic acid derivative and method for its
  申请人：Sumitomo Seika Chemicals Co., Ltd.

  公开号：US05210287A1

  公开（公告）日：1993-05-11

  The present invention is directed to novel 2,5-dichlorophenylthioglycolic acid derivative, a process for their production and a process for producing the desired product 2,5-dichlorophenylthioglycolic acid derived from said novel compounds. 2,5-dichlorophenylthioglycolic acid derivative of the present invention can be obtained by reacting 2,4,5-trichlorobenzensulfonates and thioglycolic acid in the presence of base, and said desired product can be obtained by desulfonating said compound in an aqueous solution of mineral acid. Novel 4-carboxymethylthio-2,5-dichlorobenzenesulfonates of the present invention can be used advantageously as an intermediate for the production of 2,5-dichlorophenylthioglycolic acid. The use of said intermediate makes it possible to obtain the desired product in a decreased process steps with high yield. In addition, it poses no problem of environmental pollution as pointed out with conventional methods because it uses no heavy metals.

  本发明涉及一种新型2,5-二氯苯硫代乙酸衍生物，其制备方法以及从所述新化合物中得到所需产物2,5-二氯苯硫代乙酸的方法。本发明的2,5-二氯苯硫代乙酸衍生物可通过在碱的存在下反应2,4,5-三氯苯磺酸盐和硫代乙酸来获得，所述所需产物可通过在矿酸水溶液中脱磺化所述化合物来获得。本发明的新型4-羧甲基硫基-2,5-二氯苯磺酸盐可以优势地用作生产2,5-二氯苯硫代乙酸的中间体。使用该中间体可以在减少的工艺步骤中高产率地获得所需产物。此外，它不像传统方法那样存在环境污染问题，因为它不使用重金属。