UDP-4-dehydro-6-deoxy-D-glucose | 13094-28-5

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: UDP-4-dehydro-6-deoxy-D-glucose
• 英文别名: [(2R,3R,4R,6R)-3,4-dihydroxy-6-methyl-5-oxooxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
• CAS: 13094-28-5
• 化学式: C₁₅H₂₂N₂O₁₆P₂
• 分子量: 548.29
• InChiKey: DDWGQQADOIMFOI-JPHISPRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.7
• 重原子数：
  35
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  268
• 氢给体数：
  7
• 氢受体数：
  16

文献信息

• METHODE DE BIOSYNTHESE DE LA DIOSMINE ET/OU DE L'HESPERIDINE DANS UN MICROORGANISME
  申请人：Les Laboratoires Servier

  公开号：EP3924498A1

  公开（公告）日：2021-12-22
• MONBRETIN A (MBA) SYNTHESIS USING A HETEROLOGOUS NUCLEIC ACID(S) ENCODING A MBA PATHWAY ENZYME
  申请人：The University of British Columbia

  公开号：US20210317497A1

  公开（公告）日：2021-10-14

  Provided are transgenic organisms, such as plants and plant parts, cells, and related compositions and methods for producing and monitoring the genotype for enhanced production of montbretin A and/or its precursors. For example, provided is a transgenic organism comprising at least one heterologous nucleic acid operatively linked to a promoter, wherein the heterologous nucleic acid encodes at least one enzyme in a montbretin A (MbA) metabolic pathway. The organisms can be a plant, plant part, or plant cell, or a microorganism such as a yeast. Also provided is a method for producing at least one montbretin A (MbA) precursor and/or MbA, comprising permitting the expression of the at least one heterologous nucleic acid in the transgenic organism. The disclosure also provides isolated nucleic acid molecules that comprise sequence encoding at least one enzyme in a montbretin A (MbA) metabolic pathway and vectors comprising the nucleic acids.
• [EN] MONBRETIN A (MBA) SYNTHESIS USING A HETEROLOGOUS NUCLEIC ACID(S) ENCODING A MBA PATHWAY ENZYME<br/>[FR] SYNTHÈSE DE MONBRÉTINE A (MBA) À L'AIDE D'UN ACIDE NUCLÉIQUE HÉTÉROLOGUE (D'ACIDES NUCLÉIQUES HÉTÉROLOGUES) CODANT POUR UNE ENZYME DE LA VOIE MBA
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2019241895A1

  公开（公告）日：2019-12-26

  Provided are transgenic organisms, such as plants and plant parts, cells, and related compositions and methods for producing and monitoring the genotype for enhanced production of montbretin A and/or its precursors. For example, provided is a transgenic organism comprising at least one heterologous nucleic acid operatively linked to a promoter, wherein the heterologous nucleic acid encodes at least one enzyme in a montbretin A (MbA) metabolic pathway. The organisms can be a plant, plant part, or plant cell, or a microorganism such as a yeast. Also provided is a method for producing at least one montbretin A (MbA) precursor and/or MbA, comprising permitting the expression of the at least one heterologous nucleic acid in the transgenic organism. The disclosure also provides isolated nucleic acid molecules that comprise sequence encoding at least one enzyme in a montbretin A (MbA) metabolic pathway and vectors comprising the nucleic acids.
• [EN] METHOD FOR THE BIOSYNTHESIS OF DIOSMIN AND/OR HESPERIDIN IN A MICROORGANISM<br/>[FR] METHODE DE BIOSYNTHESE DE LA DIOSMINE ET/OU DE L'HESPERIDINE DANS UN MICROORGANISME
  申请人：SERVIER LAB

  公开号：WO2020165189A1

  公开（公告）日：2020-08-20

  La présente invention est relative à un microorganisme recombinant modifié pour être capable de produire de la diosmine et de l'hespéridine et à son utilisation pour la production de diosmine et/ou d'hespéridine.
• [EN] METHODS AND COMPOSITIONS<br/>[FR] PROCÉDÉS ET COMPOSITIONS
  申请人：[en]PLANT BIOSCIENCE LIMITED

  公开号：WO2022136563A2

  公开（公告）日：2022-06-30

  The present invention relates to a biosynthetic route to intermediates of the QS-21 molecule, as well as routes to make the QS-21 molecule, enzymes involved, the products produced and uses of the product.