N,N-dimethyl-N'-(4-methylphenyl)methanimidamide hydrochloride | 10547-14-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-dimethyl-N'-(4-methylphenyl)methanimidamide hydrochloride
• 英文别名: N,N-dimethyl-N'-(4-methylphenyl)methanimidamide;hydrochloride
• CAS: 10547-14-5
• 化学式: C₁₀H₁₅N₂*Cl
• 分子量: 198.695
• InChiKey: GWZXUUSMIGZTMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.64
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  15.6
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(4-甲基苯基)-3-苯基脲 、 N,N-二甲基甲酰胺 生成 N,N-dimethyl-N'-(4-methylphenyl)methanimidamide hydrochloride
  参考文献：
  名称：

  BITTER I.; KARPATI-ADAM E.; TOKE L., ACTA CHIM. ACAD. SCI. HUNG., 1979, 102, NO 3, 235-246

  摘要：

  DOI：

文献信息

• Mild synthesis of N′-aryl-N,N-dimethylformamidinium chloride by Vilsmeier–Haack reagent
  作者：Ge Meng、Yao Wu Sha、Rui Zhang、Nan Bai

  DOI：10.1016/j.cclet.2011.03.009

  日期：2011.9

  Formamidine derivatives could be used as the building blocks for substituted heterocyclic compounds with various biological activities. N'-Aryl-N,N-dimethylformamidinium chlorides have been synthesized in high yields by reaction of aromatic primary amines with Vilsmeier-Haack reagent at room temperature. The structures of all the new compounds were identified by ESI-MS, IR and NMR spectra. The steric structures of some of these compounds were clarified by X-ray single crystal analysis. (C) 2011 Yao Wu Sha. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
• BITTER I.; KARPATI-ADAM E.; TOKE L., ACTA CHIM. ACAD. SCI. HUNG., 1979, 102, NO 3, 235-246
  作者：BITTER I.、 KARPATI-ADAM E.、 TOKE L.

  DOI：——

  日期：——