[二苯基(邻甲苯基)膦]氯化金(I) | 147454-49-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: [二苯基(邻甲苯基)膦]氯化金(I)
• 英文名称: (L3)AuCl
• 英文别名: (2-MeC6H4)Ph2PAuCl；ClAuPPh2(o-tolyl)；Gold(1+);(2-methylphenyl)-diphenylphosphane;chloride
• CAS: 147454-49-7
• 化学式: C₁₉H₁₇AuClP
• 分子量: 508.737
• InChiKey: AIYRJPLSTPNKEA-UHFFFAOYSA-M

物化性质

• 熔点：
  194-197°C

计算性质

• 辛醇/水分配系数(LogP)：
  4.44
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• MIXED LIGAND GOLD(I) COMPLEXES AS ANTI-CANCER AGENTS
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US20170305942A1

  公开（公告）日：2017-10-26

  Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

  Gold(I)复合物与混合配体一起作为抗癌剂。金(I)离子配位到一个二硫代氨基甲酸盐配体和一个含磷配体（例如磷化物）。还描述了包含金(I)复合物的药物组合物、合成金(I)复合物的方法以及治疗癌症的方法。
• Mixed ligand gold(I) complexes as anti-cancer agents
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US10077280B2

  公开（公告）日：2018-09-18

  Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

  作为抗癌剂的混合配体金（I）络合物。金（I）离子与二硫代氨基甲酸配体和含磷配体（如膦）配位。还描述了一种含有金（I）配合物的药物组合物、合成金（I）配合物的方法和治疗癌症的方法。
• Gold complexes of alkylated phosphines
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US10144749B2

  公开（公告）日：2018-12-04

  Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

  作为抗癌剂的混合配体金（I）络合物。金（I）离子与二硫代氨基甲酸配体和含磷配体（如膦）配位。还描述了一种含有金（I）配合物的药物组合物、合成金（I）配合物的方法和治疗癌症的方法。
• Cancer cell-containing composition
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US10273257B2

  公开（公告）日：2019-04-30

  Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

  作为抗癌剂的混合配体金（I）络合物。金（I）离子与二硫代氨基甲酸配体和含磷配体（如膦）配位。还描述了一种含有金（I）配合物的药物组合物、合成金（I）配合物的方法和治疗癌症的方法。
• Mononucleotide-dithiocarbamate complex
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US10280187B2

  公开（公告）日：2019-05-07

  Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

  作为抗癌剂的混合配体金（I）络合物。金（I）离子与二硫代氨基甲酸配体和含磷配体（如膦）配位。还描述了一种含有金（I）配合物的药物组合物、合成金（I）配合物的方法和治疗癌症的方法。