3-(2,4-Dimethoxyphenyl)-2-methyl-1-propene | 951891-11-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(2,4-Dimethoxyphenyl)-2-methyl-1-propene
• 英文别名: 2,4-dimethoxy-1-(2-methylprop-2-enyl)benzene
• CAS: 951891-11-5
• 化学式: C₁₂H₁₆O₂
• mdl: MFCD09801178
• 分子量: 192.25
• InChiKey: YCQDXMREHCOLOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] METHODS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION, AND SCREENING ASSAYS FOR IDENTIFYING COMPOSITIONS FOR TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION<br/>[FR] PROCÉDÉS DE TRAITEMENT D'UNE INFECTION PAR UN VIRUS DE LA FAMILLE DES FLAVIVIRIDAE, COMPOSITIONS POUR TRAITER UNE INFECTION PAR UN VIRUS DE LA FAMILLE DES FLAVIVIRIDAE, ET TESTS D'IDENTIFICATION PAR CRIBLAGE DES COMPOSITIONS POUR TRAITE
  申请人：UNIV STANFORD

  公开号：WO2009039246A2

  公开（公告）日：2009-03-26

  Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of identifying a candidate agent for the treatment of hepatitis C virus (HCV) infection, and the like.
• [EN] METHODS AND COMPOSITIONS OF TREATING A FLAVIVIRIDAE FAMILY VIRAL INFECTION<br/>[FR] MÉTHODES ET COMPOSITIONS POUR TRAITER L'INFECTION PAR UN VIRUS DE LA FAMILLE DES FLAVIVIRIDAE
  申请人：UNIV LELAND STANFORD JUNIOR

  公开号：WO2010107739A2

  公开（公告）日：2010-09-23

  Clemizole and clemizole analog compounds, and pharmaceutical compositions of the same, are useful in methods of treating a host infected with a virus from the Flaviviridae family of viruses, methods of inhibiting HCV replication in a host, methods of inhibiting the binding of NS4B polypeptide to the 3'UTR of HCV negative strand RNA in a host, and methods of treating liver fibrosis in a host.