6-[([2,2'-Bipyridin]-4-yl)amino]hexanoic acid | 340721-89-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-[([2,2'-Bipyridin]-4-yl)amino]hexanoic acid
• 英文别名: 6-[(2-pyridin-2-ylpyridin-4-yl)amino]hexanoic acid
• CAS: 340721-89-3
• 化学式: C₁₆H₁₉N₃O₂
• 分子量: 285.34
• InChiKey: NIUJVANWZHQLAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  75.1
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Redox Polymers
  申请人：Mao Fei

  公开号：US20110303538A1

  公开（公告）日：2011-12-15

  Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

  介绍了铁、钴、钌、锇和钒的新型过渡金属配合物。这些过渡金属配合物可用作酶基电化学传感器中的氧化还原媒介物。在这种情况下，过渡金属配合物可以以高速从酶中接受电子，或将电子转移给酶，并且还可以与传感器快速交换电子。这些过渡金属配合物包括至少一个取代或未取代的双咪唑配体，并且可能还包括第二个取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶咪唑配体。还介绍了连接到聚合物骨架上的过渡金属配合物。
• Transition Metal Complexes with Bidentate Ligand Having an Imidazole Ring
  申请人：Mao Fei

  公开号：US20100288634A1

  公开（公告）日：2010-11-18

  Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

  描述了铁、钴、钌、锇和钒的新型过渡金属配合物。这些过渡金属配合物可以用作基于酶的电化学传感器中的氧化还原介质。在这种情况下，过渡金属配合物以高速从酶中接受电子或向酶转移电子，并且与传感器迅速交换电子。过渡金属配合物包括至少一个取代或未取代的双咪唑配体，并且还可以包括第二个取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶咪唑配体。还描述了连接到聚合物骨架上的过渡金属配合物。
• Redox polymers
  申请人：Abbott Diabetes Care Inc.

  公开号：US10219730B2

  公开（公告）日：2019-03-05

  Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

  介绍了铁、钴、钌、锇和钒的新型过渡金属络合物。这些过渡金属配合物可用作基于酶的电化学传感器中的氧化还原媒介。在这种情况下，过渡金属络合物能从酶中高速接受电子或将电子传递给酶，同时还能与传感器快速交换电子。过渡金属配合物包括至少一种取代或未取代的双咪唑配体，还可包括第二种取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶基咪唑配体。此外，还介绍了附着在聚合物骨架上的过渡金属配合物。
• Transition metal complexes with bidentate ligand having an imidazole ring
  申请人：TheraSense, Inc.

  公开号：US20040040840A1

  公开（公告）日：2004-03-04

  Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

  介绍了铁、钴、钌、锇和钒的新型过渡金属络合物。这些过渡金属配合物可用作基于酶的电化学传感器中的氧化还原媒介。在这种情况下，过渡金属络合物能从酶中高速接受电子或将电子传递给酶，同时还能与传感器快速交换电子。过渡金属配合物包括至少一种取代或未取代的双咪唑配体，还可包括第二种取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶基咪唑配体。此外，还介绍了附着在聚合物骨架上的过渡金属配合物。
• TRANSITION METAL COMPLEXES WITH BIDENTATE LIGAND HAVING AN IMIDAZOLE RING
  申请人：Therasense, Inc.

  公开号：EP1230249B1

  公开（公告）日：2004-06-02