申请人:Nakamura Hideaki
公开号:US20050247573A1
公开(公告)日:2005-11-10
The biosensors of the present invention comprise an electrically insulating substrate, an electrically insulating cover connected to the substrate via a spacer layer, a reaction-detecting section formed on the substrate at a region sandwiched between the substrate and cover, and comprising at least one set of electrodes, and an external terminal to be connected to the reaction-detecting section, and a sealed sample-feeding path defined between the substrate and cover by the spacer layer, where the sample-feeding path has a portion intersecting the electrodes, as well as a cutting plane line provided at an outermost surface of the substrate or cover, which is a boundary between a sensor portion comprising electrodes and a sealed cap portion which does not comprise electrodes, and the cutting plane line is present at a position where, when the sealed cap portion is cut along the cutting plane line, the cut surface does not cross the electrodes and does cross the sample-feeding path, so that a sample-inlet port and an air-discharge port leading from the sample-feeding path are exposed through the cut surface. In addition, the biosensors for simultaneously measuring multiple items of the present invention comprise: a substrate; a cover connected to the substrate via a spacer layer; and a number of biosensor units comprising substrates each containing at least one biosensor unit which comprises a reaction-detecting section including one electrode system and one reagent layer on the substrate, and a sample-feeding path including the reagent layer, wherein each of the biosensor units comprise one reagent layer on one sample-feeding path, a cutting plane line for dividing each of the biosensor unit-comprising substrates is provided at a top surface of the substrate or cover, the cutting plane line and sample-feeding path are placed such that, when the substrate or cover is cut along the cutting plane line, a sample-inlet port for supplying a sample solution is open to a cut surface of each biosensor unit-comprising substrate as a cut port of the sample-feeding path.
本发明的生物传感器包括电绝缘基板、通过间隔层与基板连接的电绝缘盖板、在基板和盖板之间夹层区域的基板上形成的反应检测部分,该部分包括至少一组电极和与反应检测部分连接的外部端子,以及通过间隔层在基板和盖板之间限定的密封进样路径,其中进样路径有一部分与电极相交、以及在基板或盖的最外表面设置的切割平面线,该切割平面线是包括电极的传感器部分与不包括电极的密封盖部分之间的分界线,切割平面线位于沿切割平面线切割密封盖部分时,切割面不与电极相交而与进样路径相交的位置,这样,从进样路径引出的进样口和排气口就通过切割面暴露出来。此外,本发明用于同时测量多个项目的生物传感器包括基底; 通过间隔层与基底连接的盖子;和若干生物传感器单元,包括基板,每个基板包含至少一个生物传感器单元,该生物传感器单元包括反应检测部分(包括基板上的一个电极系统和一个试剂层),以及样品进样路径(包括试剂层),其中每个生物传感器单元包括一个样品进样路径上的一个试剂层、在基板或盖板的顶面设有用于分割每个由生物传感器单元组成的基板的切割平面线,切割平面线和进样路径的设置使得当基板或盖板沿切割平面线被切割时,用于提供样品溶液的进样口作为进样路径的切割口向每个由生物传感器单元组成的基板的切割面开放。