(3E)-6-methoxy-3-[(4-methylphenyl)methylidene]chromen-4-one | 1194283-22-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 高异黄酮
• 英文名称: (3E)-6-methoxy-3-[(4-methylphenyl)methylidene]chromen-4-one
• CAS: 1194283-22-1
• 化学式: C₁₈H₁₆O₃
• 分子量: 280.323
• InChiKey: HMDKWKAXEZLZTA-NTEUORMPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  肌氨酸 、 (3E)-6-methoxy-3-[(4-methylphenyl)methylidene]chromen-4-one 、 苊醌 以 甲醇 、 水 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  A facile entry into a novel class of dispiroheterocyclic framework through 1,3-dipolarcycloaddition of azomethine ylides with 3-arylidene-4-chromanones as dipolarophiles

  摘要：

  The cycloaddition reaction of azomethine ylides, generated through decarboxylation, with (E)-3-arylidene-4-chromanones as dipolarophiles has been investigated. A high degree of regioselectivity has been observed in the synthesis of a new class of functionalized dispiroheterocyclic compounds bearing chromanone and acenaphthenequinone framework. The structures were established by spectroscopic techniques as well as single crystal X-ray analysis. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.08.010

文献信息

• A facile entry into a novel class of dispiroheterocyclic framework through 1,3-dipolarcycloaddition of azomethine ylides with 3-arylidene-4-chromanones as dipolarophiles
  作者：T. Augustine、Charles C. Kanakam、Scholastica Mary Vithiya、V. Ramkumar

  DOI：10.1016/j.tetlet.2009.08.010

  日期：2009.10

  The cycloaddition reaction of azomethine ylides, generated through decarboxylation, with (E)-3-arylidene-4-chromanones as dipolarophiles has been investigated. A high degree of regioselectivity has been observed in the synthesis of a new class of functionalized dispiroheterocyclic compounds bearing chromanone and acenaphthenequinone framework. The structures were established by spectroscopic techniques as well as single crystal X-ray analysis. (C) 2009 Elsevier Ltd. All rights reserved.