(2,5-Dioxopyrrolidin-1-yl) 2-[7-(diethylamino)-2-oxochromen-3-yl]benzimidazole-1-carboxylate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: (2,5-Dioxopyrrolidin-1-yl) 2-[7-(diethylamino)-2-oxochromen-3-yl]benzimidazole-1-carboxylate
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 2-[7-(diethylamino)-2-oxochromen-3-yl]benzimidazole-1-carboxylate
• 化学式: C₂₅H₂₂N₄O₆
• 分子量: 474.5
• InChiKey: XZKGCVCVYMFGOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  35
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  111
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
  申请人：Waters Technologies Corporation

  公开号：US10416166B2

  公开（公告）日：2019-09-17

  Reagents comprising MS active, fluorescent molecules with an activate functionality for reaction with amines useful in rapid tagging of biomolecules such as N-glycans, proteins, peptides, and amino acids, and uses thereof are taught and described. These MS active, fluorescent molecules may have three functional components such as a tertiary amino group or other MS active atom, a highly fluorescent moiety, and a functional group that rapidly reacts with amines.

  本文教导并描述了由 MS 活性荧光分子组成的试剂，这些分子具有与胺反应的活化功能，可用于快速标记 N-聚糖、蛋白质、肽和氨基酸等生物大分子及其用途。这些具有 MS 活性的荧光分子可能具有三种功能成分，如三级氨基或其他 MS 活性原子、高荧光分子和可与胺快速反应的功能基团。
• RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS
  申请人：Waters Technologies Corporation

  公开号：US20140179011A1

  公开（公告）日：2014-06-26

  Reagents comprising MS active, fluorescent molecules with an activated functionality for reaction with amines useful in tagging biomolecules such as N-glycans and uses thereof are taught and described.
• US9772333B2
  申请人：——

  公开号：US9772333B2

  公开（公告）日：2017-09-26