3-[(4-Methoxyphenyl)methyl-diphenylphosphaniumyl]benzenesulfonate | 1070879-03-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[(4-Methoxyphenyl)methyl-diphenylphosphaniumyl]benzenesulfonate
• CAS: 1070879-03-6
• 化学式: C₂₆H₂₃O₄PS
• 分子量: 462.506
• InChiKey: NAEWOZYIIPLVMO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  74.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-[(4-Methoxyphenyl)methyl-diphenylphosphaniumyl]benzenesulfonate 、 3,5-二甲氧基苯甲醛 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 反应 0.08h， 生成 3,4',5-三甲氧基-反-二苯代乙烯 、 3-(二苯基氧膦基)苯磺酸钠 、 顺式白藜芦醇三甲醚
  参考文献：
  名称：

  Zwitterionic Phosphonium Sulfonates as Easily Phase-Separable Ion-Tagged Wittig Reagents

  摘要：

  Zwitterionic phosphonium sulfonates 3, conveniently derived from TPPMS (1), can be used as Wittig reagents in solution. The excess reagents and byproduct TPPMSO (6) can be easily separated from the product alkenes by simple precipitation With a less polar solvent. The alkenes thus obtained were often sufficiently pure without chromatographic purification. A one-pot protocol for the synthesis of alpha,beta-unsaturated esters has been developed and appears to be convenient.

  DOI：

  10.1021/jo801418a
• 作为产物：
  描述：

  sodium 3-(diphenylphosphanyl)benzenesulfonate 、 4-甲氧基溴苄 生成 3-[(4-Methoxyphenyl)methyl-diphenylphosphaniumyl]benzenesulfonate
  参考文献：
  名称：

  Zwitterionic Phosphonium Sulfonates as Easily Phase-Separable Ion-Tagged Wittig Reagents

  摘要：

  Zwitterionic phosphonium sulfonates 3, conveniently derived from TPPMS (1), can be used as Wittig reagents in solution. The excess reagents and byproduct TPPMSO (6) can be easily separated from the product alkenes by simple precipitation With a less polar solvent. The alkenes thus obtained were often sufficiently pure without chromatographic purification. A one-pot protocol for the synthesis of alpha,beta-unsaturated esters has been developed and appears to be convenient.

  DOI：

  10.1021/jo801418a

文献信息

• Zwitterionic Phosphonium Sulfonates as Easily Phase-Separable Ion-Tagged Wittig Reagents
  作者：Congde Huo、Xun He、Tak Hang Chan

  DOI：10.1021/jo801418a

  日期：2008.11.7

  Zwitterionic phosphonium sulfonates 3, conveniently derived from TPPMS (1), can be used as Wittig reagents in solution. The excess reagents and byproduct TPPMSO (6) can be easily separated from the product alkenes by simple precipitation With a less polar solvent. The alkenes thus obtained were often sufficiently pure without chromatographic purification. A one-pot protocol for the synthesis of alpha,beta-unsaturated esters has been developed and appears to be convenient.