butyl difluoro(phenylseleno)methyl ether

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: butyl difluoro(phenylseleno)methyl ether
• 英文别名: [Butoxy(difluoro)methyl]selanylbenzene
• 化学式: C₁₁H₁₄F₂OSe
• 分子量: 279.188
• InChiKey: AITPNDARBGRTKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.38
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  difluoromethyl phenyl selenoxide 以12%的产率得到
  参考文献：
  名称：

  Uneyama Kenji, Maeda Kazuhiro, Tokunaga Yukio, Itano Nobuaki, J. Org. Chem., 60 (1995) N 2, S 370-375

  摘要：

  DOI：

文献信息

• Reaction of Difluoromethyl Phenyl Selenoxide with Acetic Anhydride. A Route to Difluoro(phenylseleno)methylation of Ethers
  作者：Kenji Uneyama、Kazuhiro Maeda、Yukio Tokunaga、Nobuaki Itano

  DOI：10.1021/jo00107a016

  日期：1995.1

  Difluoromethyl phenyl selenoxide (2) has been prepared and allowed to react with acetic anhydride in the presence of cyclic ethers and sulfides. Difluorophenylselenomethylation occurred smoothly on reacting 2 with Ac2O in refluxing dichloromethane to give omega-[difluoro(phenylseleno)methoxy]alkyl acetates 4 in 34-87% yields. A sequential reaction of Pummerer type rearrangement, difluorocarbene formation, electrophilic addition of the carbene to oxygen of ethers leading to oxonium ylide, and trapping with phenylselenenyl acetate is proposed.
• Uneyama Kenji, Maeda Kazuhiro, Tokunaga Yukio, Itano Nobuaki, J. Org. Chem., 60 (1995) N 2, S 370-375
  作者：Uneyama Kenji, Maeda Kazuhiro, Tokunaga Yukio, Itano Nobuaki

  DOI：——

  日期：——