5-iodo-2-thiocyanatothiophene

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 5-iodo-2-thiocyanatothiophene
• 英文别名: (5-Iodothiophen-2-yl) thiocyanate
• 化学式: C₅H₂INS₂
• 分子量: 267.114
• InChiKey: AQIKVQZWMGCQPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-碘噻吩 、 N-thiocyanatosuccinimide 以 溶剂黄146 为溶剂， 反应 4.0h， 生成 5-iodo-2-thiocyanatothiophene
  参考文献：
  名称：

  A Versatile Procedure for the Preparation of Aryl Thiocyanates Using N-Thiocyanatosuccinimide (NTS)

  摘要：

  A mild procedure for the thiocyanation of several types of arene substrate using N-thiocyanatosuccinimide (NTS) is described. The method appears generally applicable to benzenoid substrates with a wide range of substituents, as well as to heteroaromatic analogues such as indoles and thiophenes.

  DOI：

  10.1080/00397919508012691

文献信息

• Toste F. Dean, De Stefano Vittorio, Still Ian W. J., Synth. Commun, 25 (1995) N 8, S 1277-1286
  作者：Toste F. Dean, De Stefano Vittorio, Still Ian W. J.

  DOI：——

  日期：——
• A Versatile Procedure for the Preparation of Aryl Thiocyanates Using N-Thiocyanatosuccinimide (NTS)
  作者：F. Dean Toste、Vittorio De Stefano、Ian W. J. Still

  DOI：10.1080/00397919508012691

  日期：1995.4

  A mild procedure for the thiocyanation of several types of arene substrate using N-thiocyanatosuccinimide (NTS) is described. The method appears generally applicable to benzenoid substrates with a wide range of substituents, as well as to heteroaromatic analogues such as indoles and thiophenes.