2-[[(1S,5R)-5-(2-carboxyanilino)-4-oxocyclopent-2-en-1-yl]amino]benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[[(1S,5R)-5-(2-carboxyanilino)-4-oxocyclopent-2-en-1-yl]amino]benzoic acid
• 化学式: C₁₉H₁₆N₂O₅
• 分子量: 352.346
• InChiKey: VUEWEFGPBIWPIJ-DOTOQJQBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-[[(1S,5R)-5-(2-carboxyanilino)-4-oxocyclopent-2-en-1-yl]amino]benzoic acid 在 铜 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  A highly selective and sensitive turn-on catalytic chemodosimeter for Cu2+ in aqueous solution

  摘要：

  We report herein the first diaininocyciopent-2-eiioile-based catalytic chernoclosimeter (3) for naked-eye and turn-on fluorescent detections of Cu2+ in pure aqueous solution. Compound 3 easily made available from furan-2-carbaldehyde and 2-aminobenzoic acid was found to show a highly selective and sensitive response toward Cu2+ by way Of Cu2+-coordination promoted formation of Stenhouse salt and subsequent decomposition to highly fluorescent 2-aminobenzoate. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.10.050
• 作为产物：
  描述：

  糠醛 、 邻氨基苯甲酸 以 乙醇 为溶剂， 反应 24.0h， 以85%的产率得到2-[[(1S,5R)-5-(2-carboxyanilino)-4-oxocyclopent-2-en-1-yl]amino]benzoic acid
  参考文献：
  名称：

  A highly selective and sensitive turn-on catalytic chemodosimeter for Cu2+ in aqueous solution

  摘要：

  We report herein the first diaininocyciopent-2-eiioile-based catalytic chernoclosimeter (3) for naked-eye and turn-on fluorescent detections of Cu2+ in pure aqueous solution. Compound 3 easily made available from furan-2-carbaldehyde and 2-aminobenzoic acid was found to show a highly selective and sensitive response toward Cu2+ by way Of Cu2+-coordination promoted formation of Stenhouse salt and subsequent decomposition to highly fluorescent 2-aminobenzoate. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.10.050