2-methoxy-4-methyl-6(2,3-dimethoxy-5-methylbenzyl)phenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methoxy-4-methyl-6(2,3-dimethoxy-5-methylbenzyl)phenol
• 英文别名: 2-(2,3-dimethoxy-5-methylbenzyl)-6-methoxy-4-methylphenol；2-[(2,3-Dimethoxy-5-methylphenyl)methyl]-6-methoxy-4-methylphenol；2-[(2,3-dimethoxy-5-methylphenyl)methyl]-6-methoxy-4-methylphenol
• 化学式: C₁₈H₂₂O₄
• 分子量: 302.37
• InChiKey: AWSXVBWUCDIHKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  重氮甲烷 、 2-[(2-羟基-3-甲氧基-5-甲基苯基)甲基]-6-甲氧基-4-甲基苯酚 以 乙醚 为溶剂， 生成 2-methoxy-4-methyl-6(2,3-dimethoxy-5-methylbenzyl)phenol
  参考文献：
  名称：

  Methylthiomethylierung von Phenolen mit Dimethylsulfoxid-Pyridin-Schwefeltrioxid

  摘要：

  DOI：

  10.1007/bf01167275

文献信息

• Biomimetic degradation of lignin and lignin model compounds by synthetic anionic and cationic water soluble manganese and iron porphyrins
  作者：Claudia Crestini、Raffaele Saladino、Pietro Tagliatesta、Tristano Boschi

  DOI：10.1016/s0968-0896(99)00105-4

  日期：1999.9

  meso-tetra(N-methylpyridinio)porphyrin pentaacetate (TPyMePMn(CH3COO)5) was compared on the basis of the oxidation extent of the models tested. Manganese porphyrins were found more effective in degrading lignin substructures than iron ones. Among them the cationic TPyMePMn (CH3COO)5, never used before in lignin oxidation, showed to be the best catalyst. The catalytic activity of porphyrins in hydrogen peroxide

  据报道，在过氧化氢的存在下，几种水溶性的阴离子和阳离子铁和锰卟啉可对5-5'缩合和二苯甲烷木质素模型化合物进行仿生氧化。锰和铁的中-四（2,6-二氯-3-磺基苯基）卟啉氯化物（分别为TDCSPPMnCl和TDCSPPFeCl），中-四-3-磺基苯基卟啉氯化物（TSPPMnCl）和锰的中-四（N根据所测试模型的氧化程度，比较了-甲基吡啶基）卟啉五乙酸盐（TPyMePMn（CH3COO）5）。发现锰卟啉在降解木质素亚结构方面比铁更有效。其中，以前从未在木质素氧化中使用过的阳离子TPyMePMn（CH3COO）5是最好的催化剂。还研究了卟啉在残留硫酸盐木质素的过氧化氢氧化中的催化活性。定量31P NMR的使用可以根据所使用的催化剂，专注于发生不同的降解途径。TPyMePMn（CH3COO）5能够对木质素结构进行最广泛的降解，脂族羟基和羧酸的减少证明了这一点。值得注意的是，在锰卟啉催化残留的硫酸盐
• Immobilized methyltrioxo rhenium (MTO)/H2O2 systems for the oxidation of lignin and lignin model compounds
  作者：Claudia Crestini、Maria Chiara Caponi、Dimitris S. Argyropoulos、Raffaele Saladino

  DOI：10.1016/j.bmc.2006.03.046

  日期：2006.8

  A convenient and efficient application of heterogeneous methylrhenium trioxide (MTO) systems for the selective oxidation of lignin model compounds and lignins is reported. Environmental friendly and low-cost H2O2 was used as the oxygen atom donor. Overall, the data presented and discussed in this paper point toward the conclusion that the immobilized heterogeneous catalytic systems based on H2O2/and MTO catalysts are able to extensively oxidize both phenolic and non-phenolic, monomeric, and dimeric, lignin model compounds. Condensed diphenylmethane models were found also extensively oxidized. Technical lignins, such as hydrolytic sugar cane lignin (SCL) and red spruce kraft lignin (RSL), displayed oxidative activity with immobilized MTO catalytic systems. After oxidation, these lignins displayed the formation of more soluble lignin fragments with a high degree of degradation as indicated by the lower contents of aliphatic and condensed OH groups, and the higher amounts of carboxylic acid moieties. Our data indicate that immobilized MTO catalytic systems are significant potential candidates for the development of alternative totally chlorine-free delignification processes and environmentally sustainable lignin selective modification reactions. (c) 2006 Elsevier Ltd. All rights reserved.
• Methylthiomethylierung von Phenolen mit Dimethylsulfoxid-Pyridin-Schwefeltrioxid
  作者：P. Claus

  DOI：10.1007/bf01167275

  日期：1971.5