(R)-2,2′-diethoxy-1,1′-binaphthyl-4,4′,6,6′-tetracarbonitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (R)-2,2′-diethoxy-1,1′-binaphthyl-4,4′,6,6′-tetracarbonitrile
• 化学式: C₂₈H₁₈N₄O₂
• 分子量: 442.477
• InChiKey: AWTQHZGLRRDLJM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.94
• 重原子数：
  34.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  113.62
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (R)-2,2′-diethoxy-1,1′-binaphthyl-4,4′,6,6′-tetracarbonitrile 、 二聚氰胺 在 potassium hydroxide 作用下， 以 乙二醇甲醚 为溶剂， 反应 24.0h， 以52%的产率得到(R)-4,4′,6,6′-tetra-(2,4-diamino-1,3,5-triazin-6-yl)-2,2′-diethoxy-1,1′-binaphthalene
  参考文献：
  名称：

  A Homochiral Microporous Hydrogen-Bonded Organic Framework for Highly Enantioselective Separation of Secondary Alcohols

  摘要：

  A homochiral microporous hydrogen. bonded organic framework (HOF-2) based on a BINOL derivative has been synthesized and structurally characterized to be a uninodal 6-connected {3(3)5(5)6(6)7} network. This new HOF exhibits not only a permanent porosity with the BET of 237.6 m(2) g(-1) but also, more importantly, a highly enantioselective separation of chiral secondary alcohols with ee value up to 92% for 1-phenylethanol.

  DOI：

  10.1021/ja4129795
• 作为产物：
  描述：

  (R)-1,1'-Bi-2-naphthol 在 溴 、 potassium carbonate 、 溶剂黄146 作用下， 以 N,N-二甲基甲酰胺 、 丙酮 为溶剂， 反应 72.0h， 生成 (R)-2,2′-diethoxy-1,1′-binaphthyl-4,4′,6,6′-tetracarbonitrile
  参考文献：
  名称：

  A Homochiral Microporous Hydrogen-Bonded Organic Framework for Highly Enantioselective Separation of Secondary Alcohols

  摘要：

  A homochiral microporous hydrogen. bonded organic framework (HOF-2) based on a BINOL derivative has been synthesized and structurally characterized to be a uninodal 6-connected {3(3)5(5)6(6)7} network. This new HOF exhibits not only a permanent porosity with the BET of 237.6 m(2) g(-1) but also, more importantly, a highly enantioselective separation of chiral secondary alcohols with ee value up to 92% for 1-phenylethanol.

  DOI：

  10.1021/ja4129795

文献信息

• A Homochiral Microporous Hydrogen-Bonded Organic Framework for Highly Enantioselective Separation of Secondary Alcohols
  作者：Peng Li、Yabing He、Jie Guang、Linghong Weng、John Cong-Gui Zhao、Shengchang Xiang、Banglin Chen

  DOI：10.1021/ja4129795

  日期：2014.1.15

  A homochiral microporous hydrogen. bonded organic framework (HOF-2) based on a BINOL derivative has been synthesized and structurally characterized to be a uninodal 6-connected 3(3)5(5)6(6)7} network. This new HOF exhibits not only a permanent porosity with the BET of 237.6 m(2) g(-1) but also, more importantly, a highly enantioselective separation of chiral secondary alcohols with ee value up to 92% for 1-phenylethanol.