2-(2-ethoxyethyl)benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(2-ethoxyethyl)benzoic acid
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: BJIGIOWMPCTIJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(2-ethoxyethyl)benzoic acid 在 偶氮二甲酸二异丙酯 、 N,N-二异丙基乙胺 、 三苯基膦 、 N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 18.0h， 生成 2-[[(3S)-4-[2-(2-ethoxyethyl)benzoyl]morpholin-3-yl]methoxy]-6-hydroxybenzaldehyde
  参考文献：
  名称：

  MODULATORS OF HEMOGLOBIN

  摘要：

  本公开涉及一般与血红蛋白调节剂相关的化合物和药物组合物，以及它们在治疗由血红蛋白介导的疾病中的使用方法。

  公开号：

  US20200157085A1
• 作为产物：
  描述：

  methyl 2-(2-ethoxyethyl)benzoate 在 水 、 sodium hydroxide 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 2-(2-ethoxyethyl)benzoic acid
  参考文献：
  名称：

  MODULATORS OF HEMOGLOBIN

  摘要：

  本公开涉及一般与血红蛋白调节剂相关的化合物和药物组合物，以及它们在治疗由血红蛋白介导的疾病中的使用方法。

  公开号：

  US20200157085A1

文献信息

• Process for producing stereoregular polymers having a narrow molecular weight distribution
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0291958A2

  公开（公告）日：1988-11-23

  Stereoregular polymers having a molecular weight distribution of less than 5.0 and an isotactic index in excess of 96 percent are produced by polymerizing an alpha-olefin having 3 to 8 carbon atoms in a low pressure gas phase fluid bed process at a temperature in excess of 80°C employing a heat stable catalyst system comprising (a) a solid catalyst component containing magnesium, titanium, halide and a polycarboxylic acid ester containing two coplanar ester groups attached to adjacent carbon atoms, as inside electron donor, (b) an organoaluminum cocatalyst, and (c) a silicon compound containing a silicon-oxygen-carbon linkage, as out­side electron donor.

  分子量分布小于 5.在温度超过 80°C 的低压气相流化床工艺中，采用热稳定催化剂系统聚合具有 3 至 8 个碳原子的α-烯烃，可生产出分子量分布小于 5.0、同素异形指数超过 96% 的立体状聚合物，该催化剂系统包括 (a) 固体催化剂组分，其中含有镁、钛、卤化物和聚羧酸酯，聚羧酸酯含有两个连接到相邻碳原子上的共面酯基作为催化剂、钛、卤化物和聚羧酸酯，其中聚羧酸酯含有两个连接到相邻碳原子上的共面酯基，作为内部电子供体；(b)有机铝助催化剂；(c)硅化合物，含有硅氧碳连接，作为外部电子供体。
• Process for preparing cycloolefin random copolymer
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0542488A1

  公开（公告）日：1993-05-19

  The invention provides a process for preparing a cycloolefin random copolymer comprising repeating units derived from (i) ethylene in an amount of 40 to 97% by mole, repeating units derived from (ii) a specified cycloolefin in an amount of 3 to 60% by mol and optionally repeating units derived from (iii) an α-olefin of 3 - 20 carbon atoms in an amount of 0 to 20% by mol, wherein (i) ethylene, (ii) the cycloolefin and optionally (iii) the α-olefin are copolymerized in a liquid phase in the presence of a catalyst formed from (A) a soluble vanadium compound having a tertiary alkoxy group or β-diketone as a ligand and (B) an organoaluminum compound represented by the formula (i-Bu)nAlCl3-n wherein n is 1.0 to 2.5.

  本发明提供了一种制备环烯烃无规共聚物的工艺，该共聚物包含来自(i)乙烯的重复单元（以摩尔计，含量为40-97%），来自(ii)特定环烯烃的重复单元（以摩尔计，含量为3-60%），以及可选地来自(iii)3-20个碳原子的α-烯烃的重复单元（以摩尔计，含量为0-20%）、其中(i)乙烯、(ii)环烯烃和任选的(iii)α-烯烃在液相中在催化剂存在下共聚，催化剂由(A)具有叔烷氧基或β-二酮作为配位体的可溶性钒化合物和(B)由式(i-Bu)nAlCl3-n表示的有机铝化合物组成，其中n为1.0至2．
• CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0597119A1

  公开（公告）日：1994-05-18

  A cycloolefin copolymer composition comprising a hydrocarbon elastomer component which is substantially free from any polymerizable double bond and a random cycloolefin copolymer component prepared by the copolymerization of a C₂ or higher α-olefin with a cycloolefin in the presence of said elastomer component, wherein the content of the elastomer component is 1-50 wt. %. Another cycloolefin copolymer composition comprising a hydrocarbon elastomer component having polymerizable double bonds and a cycloolefin copolymer component prepared by the copolymerization of a C₂ or higher α-olefin with a cycloolefin in the presence of said elastomer component, wherein the content of the elastomer component is 1-50 wt. %. These compositions are excellent in transparency and mechanical strengths and particularly in impact resistance.

  一种环烯烃共聚物组合物，包括基本上不含任何可聚合双键的碳氢化合物弹性体组分和无规环烯烃共聚物组分，该无规环烯烃共聚物组分是通过 C₂ 或更高α-烯烃与环烯烃在所述弹性体组分存在的情况下共聚制备的，其中弹性体组分的含量为 1-50 wt.%。另一种环烯烃共聚物组合物，包括具有可聚合双键的碳氢化合物弹性体成分和在所述弹性体成分存在下，通过 C₂ 或更高α-烯烃与环烯烃共聚制备的环烯烃共聚物成分，其中弹性体成分的含量为 1-50 wt.%。这些组合物具有优异的透明度和机械强度，尤其是抗冲击性。
• Cycloolefin polymer composition
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0608903A1

  公开（公告）日：1994-08-03

  There is provided a cycloolefin polymer composition comprising 8 to 40 % by weight of a cycloolefin polymer [A] and 92 to 60 % by weight of a cycloolefin polymer [B], both having specific properties, wherein a difference ΔnD = |nD(A) - nD(B)| between the refractive index nD(A) of the polymer [A] and the refractive index nD(B) of the polymer [B] is not more than 0.015. This composition is excellent in impact resistance, transparency and heat resistance, and has a good balance of these properties. There is also provided a cycloolefin copolymer composition comprising 8 to 40 % by weight of a cycloolefin elastomer component [Aa] of an α-olefin, a specific cycloolefin and a non-conjugated diene which contains a polymerizable carbon-carbon double bond; and 92 to 60 % by weight of a cycloolefin copolymer component [Ba] which is obtainable by copolymerizing an α-olefin and a specific cycloolefin in the presence of the elastomer component [Aa]; wherein a difference ΔnD = |nD(A) - nD(B)| between the refractive index nD(Aa) of the component [Aa] and the refractive index nD(Ba) of the component [Ba] is not more than 0.015. This composition has excellent properties inherent in a cycloolefin random copolymer and is improved especially in impact resistance without tranding off its transparency. There is also provided a cycloolefin copolymer composition comprising 8 to 40 % by weight of a cycloolefin elastomer component [Aα] of an α-olefin and a specific cycloolefin which substantially contains no polymerizable carbon-carbon double bond; and 92 to 60 % by weight of a cycloolefin copolymer component [Bα] which is obtainable by copolymerizing an α-olefin and a specific cycloolefin in the presence of the elastomer component [Aα]; wherein a difference ΔnD = |nD(A) - nD(B)| between the refractive index nD(Aα) of the component [Aα] and the refractive index nD(Bα) of the component [Bα] is not more than 0.015. This composition has also excellent properties inherent in a cycloolefin random copolymer and is improved particularly in impact resistance without trading off its transparency.

  本发明提供了一种环烯烃聚合物组合物，按重量计包含 8%至 40%的环烯烃聚合物[A]和 92%至 60%的环烯烃聚合物[B]，两者均具有特定性能，其中聚合物[A]的折射率 nD(A)与聚合物[B]的折射率 nD(B)之差ΔnD = |nD(A) - nD(B)|不大于 0.015。这种组合物具有优异的抗冲击性、透明度和耐热性，并在这些特性之间取得了良好的平衡。 还提供了一种环烯烃共聚物组合物，该组合物包含 8-40%（按重量计）的环烯烃弹性体组分[Aa]，该组分由含有可聚合碳碳双键的α-烯烃、特定环烯烃和非共轭二烯组成；和 92-60%(重量)的环烯烃共聚物组分[Ba]，该组分可通过在弹性体组分[Aa]存在下共聚α-烯烃和特定环烯烃而获得；其中组分[Aa]的折射率nD(Aa)和组分[Ba]的折射率nD(Ba)之间的差值ΔnD = |nD(A) - nD(B)|不大于0。015.这种组合物具有环烯烃无规共聚物所固有的优异性能，尤其是在抗冲击性方面得到了改善，而透明度却没有降低。 还提供了一种环烯烃共聚物组合物，该组合物包含 8-40%（重量百分比）的环烯烃 弹性体组分[Aα]，该组分由α-烯烃和特定的环烯烃组成，该环烯烃基本上不含可聚合 的碳碳双键；环烯烃共聚物组分[Bα]的重量百分比为92%至60%，该组分可通过在弹性体组分[Aα]存在下共聚α-烯烃和特定环烯烃而获得；其中组分[Aα]的折射率nD(Aα)与组分[Bα]的折射率nD(Bα)之间的差值ΔnD＝|nD(A)-nD(B)|不大于0。015.这种组合物还具有环烯烃无规共聚物所固有的优良特性，尤其是在抗冲击性方面得到了改善，但并不影响其透明度。
• POLYPROPYLENE RESIN COMPOSITION
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1647575A1

  公开（公告）日：2006-04-19

  A polypropylene resin composition comprising (A) a crystalline propylene block copolymer having a content of a room temperature n-decane-soluble portion of 15 to 35% by weight and having MFR of 5 to 80 g/10min, in an amount of 94 to 55%, (B) an elastomeric polymer in an amount of 1 to 20% by weight and (C) an inorganic filler in an amount of 5 to 25% by weight, said composition having the property that a ratio of an Izod impact strength (J/m, IZ250-30) of a specimen obtained by maintaining the composition at 250°C for 30 minutes in a molten state in an injection molding machine and then molding the composition, said Izod impact strength being measured after 48 hours from the molding, to an Izod impact strength (J/m, IZ230-3) of a specimen obtained by maintaining the composition at 230°C for 3 minutes in a molten state in the same injection molding machine and then molding the composition by the same method, said Izod impact strength being measured after 48 hours from the molding, satisfies the following formula: 1.0≥(IZ250−30/IZ230−3)≥0.5.

  一种聚丙烯树脂组合物，包括(A)结晶丙烯嵌段共聚物，其室温正癸烷可溶部分含量为 15-35%（重量比），且 MFR 为 5-80g/10min，含量为 94-55%；(B)弹性聚合物，含量为 1-20%（重量比）；以及(C)无机填料，含量为 5-25%（重量比）、IZ250-30）与通过在注塑机中将熔融状态的组合物在 250°C 下保持 30 分钟，然后将组合物成型（所述伊佐德冲击强度在成型 48 小时后测量）而获得的试样的伊佐德冲击强度（J/m、在同一注塑机中，将熔融状态下的组合物在 230°C 下保持 3 分钟，然后用同样的方法将组合物成型，在成型 48 小时后测得的试样的伊佐德冲击强度（J/m，IZ230-3）满足下式：1.0≥(IZ250−30/IZ230−3)≥0.5.