trichloro<<<4-methyl-2,6-bis(1,1-dimethylethyl)phenoxy>propenyl>oxy>silane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trichloro<<<4-methyl-2,6-bis(1,1-dimethylethyl)phenoxy>propenyl>oxy>silane
• 英文别名: trichloro-[(E)-1-(2,6-ditert-butyl-4-methylphenoxy)prop-1-enoxy]silane
• 化学式: C₁₈H₂₇Cl₃O₂Si
• 分子量: 409.856
• InChiKey: BOPWGOCVVNRDHJ-OQLLNIDSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.0
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,6-di-tert-butyl-4-methylphenyl propionate 在 Trichloro(trifluoromethylsulfonyloxy)silane 、 lithium diisopropyl amide 作用下， 以 氘代氯仿 为溶剂， 反应 42.5h， 生成 trichloro<<<4-methyl-2,6-bis(1,1-dimethylethyl)phenoxy>propenyl>oxy>silane
  参考文献：
  名称：

  Preparation of Chlorosilyl Enolates

  摘要：

  A variety of chlorosilyl enolates has been prepared starting from esters, thiol esters, acylsilanes, and ketones. Two general methods are involved, direct enolsilylation with trichlorosilyl triflate and diisopropylethylamine, and a number of methods based on electrophilic substitution of either C- or O-silyl or stannyl carbonyl compounds. The most useful method is a Hg(OAc)(2)-catalyzed trans-silylation from trimethylsilyl to trichlorosilyl enol ethers, providing a wide range of ketone enolates in good to high yield.

  DOI：

  10.1021/jo981740h

文献信息

• Preparation of Chlorosilyl Enolates
  作者：Scott E. Denmark、Robert A. Stavenger、Stephen B. D. Winter、Ken-Tsung Wong、Paul A. Barsanti

  DOI：10.1021/jo981740h

  日期：1998.12.1

  A variety of chlorosilyl enolates has been prepared starting from esters, thiol esters, acylsilanes, and ketones. Two general methods are involved, direct enolsilylation with trichlorosilyl triflate and diisopropylethylamine, and a number of methods based on electrophilic substitution of either C- or O-silyl or stannyl carbonyl compounds. The most useful method is a Hg(OAc)(2)-catalyzed trans-silylation from trimethylsilyl to trichlorosilyl enol ethers, providing a wide range of ketone enolates in good to high yield.