1,3-dioctanoyl-2-linoleoyl-sn-glycerol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,3-dioctanoyl-2-linoleoyl-sn-glycerol
• 英文别名: 1,3-dicapryloyl-2-linoleoylglycerol；2-linoleoyl-1,3-dioctanoylglycerol；1,3-capryloyl-2-linoleoyl-glycerol；1,3-Dicapryloyl-2-linoleoyl glycerol；1,3-di(octanoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
• 化学式: C₃₇H₆₆O₆
• 分子量: 606.927
• InChiKey: BTLPCOOVNVTENY-NFYLBXPESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.7
• 重原子数：
  43
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  arachidonic acid-containing triglyceride oil 、 辛酸 生成 1,3-dioctanoyl-2-linoleoyl-sn-glycerol 、 1,3-dicapryloyl-2-arachidonoyl glyceride 、 1,3-capriloyl-2-γ-linolenoyl-glycerol 、 1,3-capryloyl-2-dihomo-γ-linolenoyl-glycerol 、 2-palmitoyloxy-1,3-bis-octanoyloxy-propane 、 1,3-dicapryloyl-2-oleyl-glycerol
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Nutrient-supplying preparation
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0671166A2

  公开（公告）日：1995-09-13

  Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation, denaturation and the like in spite of the simultaneous presence of these components. Also disclosed is a container filled with infusion liquids comprising a first and a second compartments separated from each other by a separation means, wherein an infusion liquid containing a fat emulsion and a sugar is included in the first compartment and another infusion liquid containing amino acids and electrolytes is included in the second compartment. Further disclosed are an infusion preparation comprising a fat emulsion and a sugar, and an infusion preparation comprising amino acids and electrolytes. An infusion preparation containing a sugar, amino acids, electrolytes and a fat emulsion can be obtained easily and aseptically upon use, by simply removing a separation means attached to the container and mixing the two infusion liquids.

  本发明公开了一种用于营养供应的输液制剂。它由糖、氨基酸、电解质和脂肪乳液组成。尽管这些成分同时存在，但它具有极佳的保质期，不会引起沉淀、变性等现象。本发明还公开了一种装有输液的容器，该容器包括通过分离装置相互隔开的第一和第二隔室，其中第一隔室中装有一种含有脂肪乳液和糖的输液，第二隔室中装有另一种含有氨基酸和电解质的输液。进一步公开了一种包含脂肪乳液和糖的输液制剂，以及一种包含氨基酸和电解质的输液制剂。使用时，只需取下附在容器上的分离装置，将两种输液混合，即可方便无菌地获得含有糖、氨基酸、电解质和脂肪乳液的输液制剂。
• NUTRITIONAL TRANSFUSION FOR PERIPHERAL VEIN ADMINISTRATION
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0700681A1

  公开（公告）日：1996-03-13

  A nutritional transfusion that can be administered via peripheral veins and is improved in stability and conservability. It contains a saccharide, an amino acid, an electrolyte and a fat emulsion each in a specified proportion and has specified pH value and titratable acidity. It has a good conservability because it is free from precipitation and denaturation in spite of its composition comprising the above various components. Further it is free from the problem of angialgia or the like even when administered via peripheral veins, since it has a specified pH value and a low titratable acidity.

  一种可通过外周静脉输注的营养输液，其稳定性和保存性均有所提高。它包含一种糖、一种氨基酸、一种电解质和一种脂肪乳液，每种物质都有规定的比例，并有规定的 pH 值和可滴定酸度。它具有良好的保存性，因为尽管其成分包括上述各种成分，但它不会发生沉淀和变性。此外，由于它具有特定的 pH 值和较低的可滴定酸度，因此即使通过外周静脉给药，也不会出现血管痛等问题。
• TRANSFUSION CONTAINER, TRANSFUSION PREPARATION, AND COMPREHENSIVE VITAMIN-CONTAINING HIGH-CALORIE TRANSFUSION PREPARATION
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0704199A1

  公开（公告）日：1996-04-03

  A transfusion container useful for preparing a transfusion containing saccharide, amino acid, electrolyte, fat emulsion and vitamin. The container is composed of two compartments with a partitioning means provided therebetween, and a first compartment contains a transfusion containing fat emulsion, saccharide and specified vitamin, while a second compartment contains a transfusion containing amino acid, electrolyte and other specified vitamin. A transfusion preparation containing saccharide, amino acid, electrolyte, fat emulsion and vitamin can be readily and aseptically prepared by removing the partitioning means prior to use and mixing the transfusions contained in the two compartments together.

  一种输液容器，用于配制含有糖、氨基酸、电解质、脂肪乳液和维生素的输液。该容器由两个隔室组成，隔室之间设有分隔装置，第一隔室装有含脂肪乳剂、糖和特定维生素的输液，第二隔室装有含氨基酸、电解质和其他特定维生素的输液。在使用前移除分隔装置并将两个隔室中的输液混合在一起，就可以方便无菌地制备含有糖、氨基酸、电解质、脂肪乳液和维生素的输液制剂。
• TRANSFUSION LIQUID-CONTAINING HOLDER AND PREPARED TRANSFUSION LIQUID
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0747033A1

  公开（公告）日：1996-12-11

  A transfusion liquid set (transfusion liquid-containing holder) useful for preparing a transfusion liquid containing sugar, amino acid, electrolyte, fatty emulsion and vitamin. The present invention uses a holder formed so that the interior thereof is divided into two independent chambers by a partition means. A first chamber holds a transfusion liquid containing fatty emulsion, sugar, oil-soluble vitamin and specific water-soluble vitamin, and a second chamber a transfusion liquid containing amino acid, electrolyte and specific water-soluble vitamin. When a transfusion liquid is needed, the partition means is removed, and the transfusion liquids held in the first and second chambers are mixed with each other, so that a transfusion liquid containing sugar, amino acid, electrolyte, fatty emulsion and vitamin can be prepared easily and aseptically. The transfusion liquid components in each chamber have excellent stability.

  一种用于配制含糖、氨基酸、电解质、脂肪乳液和维生素的输液装置（含输液支架）。本发明使用的支架通过隔板将其内部分为两个独立的腔室。第一腔盛放含有脂肪乳液、糖、油溶性维生素和特定水溶性维生素的输液，第二腔盛放含有氨基酸、电解质和特定水溶性维生素的输液。当需要输液时，取下隔板，将第一室和第二室中的输液相互混合，这样就可以方便无菌地配制出含有糖、氨基酸、电解质、脂肪乳液和维生素的输液。每个腔室中的输液成分都具有出色的稳定性。
• Container filled with infusion liquids
  申请人：THE GREEN CROSS CORPORATION

  公开号：EP0752243A2

  公开（公告）日：1997-01-08

  Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation, denaturation and the like in spite of the simultaneous presence of these components. Also disclosed is a container filled with infusion liquids comprising a first and a second compartments separated from each other by a separation means, wherein an infusion liquid containing a fat emulsion and a sugar is included in the first compartment and another infusion liquid containing amino acids and electrolytes is included in the second compartment. Further disclosed are an infusion preparation comprising a fat emulsion and a sugar, and an infusion preparation comprising amino acids and electrolytes. An infusion preparation containing a sugar, amino acids, electrolytes and a fat emulsion can be obtained easily and aseptically upon use, by simply removing a separation means attached to the container and mixing the two infusion liquids.

  本发明公开了一种用于营养供应的输液制剂。它由糖、氨基酸、电解质和脂肪乳液组成。尽管这些成分同时存在，但它具有极佳的保质期，不会引起沉淀、变性等现象。本发明还公开了一种装有输液的容器，该容器包括通过分离装置相互隔开的第一和第二隔室，其中第一隔室中装有一种含有脂肪乳液和糖的输液，第二隔室中装有另一种含有氨基酸和电解质的输液。进一步公开了一种包含脂肪乳液和糖的输液制剂，以及一种包含氨基酸和电解质的输液制剂。使用时，只需取下附在容器上的分离装置，将两种输液混合，即可方便无菌地获得含有糖、氨基酸、电解质和脂肪乳液的输液制剂。