2-(diphenylphosphinomethyl)aminopyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-(diphenylphosphinomethyl)aminopyridine
• 英文别名: N-(diphenylphosphanylmethyl)pyridin-2-amine
• 化学式: C₁₈H₁₇N₂P
• 分子量: 292.32
• InChiKey: IUZGWCUHYDGMCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(diphenylphosphinomethyl)aminopyridine 在 cobalt (II) perchlorate hexahydrate 作用下， 以 乙腈 为溶剂， 以50%的产率得到(Diphenyl-phosphinoylmethyl)-pyridin-2-yl-amine; compound with perchloric acid
  参考文献：
  名称：

  Synthesis and structural study of late transition metal complexes of N-[(diphenylphosphino)methyl]-2-pyridinamine and N-cyclohexyl-N-[(diphenylphosphino)methyl]-2-pyridinamine

  摘要：

  N-[(联苯基膦基)甲基]-2-吡啶胺和N-环己基-N-[(联苯基膦基)甲基]-2-吡啶胺与不同化学计量比的二价钯、单价铜、单价银盐和五羰基铁反应，产生了一系列展示各种配位模式的配合物，其中包括在一个二核银配合物中出现的新型P,N（胺），N（吡啶）桥接模式，这一模式通过银亲和相互作用得以巩固。

  DOI：

  10.1039/b109191n
• 作为产物：
  描述：

  2-氨基吡啶 、 (二苯基膦基)甲醇 以 甲醇 、 甲苯 为溶剂， 反应 24.0h， 以79%的产率得到2-(diphenylphosphinomethyl)aminopyridine
  参考文献：
  名称：

  Ph 2 PCH 2 OH衍生的新型官能化吡啶基膦的合成与配位化学

  摘要：

  Ph 2 PCH 2 OH与H 2 NC 5 H 3（OH）N的缩合甲醇/甲苯 赋予了新的“混合动力” 配体Ph 2 PCH 2 N（H）C 5 H 3（OH）N Ia，将其与ClP（O）R 2（R = Ph，OPh）或ClPR 2磷酸化后得到Ph 2 PCH 2 N（H）C 5 H 3（X）N [X = OP（O）Ph 2 II ; OP（O）（OPh）2 III；OPPh 2 IV ]。氧化作用的IA用含水ħ 2 ö 2在THF中得到博士2 P（O）CH 2 N（H）C 5 H ^ 3（OH）N V。的二氯化（II）配合物1-4是从[氯铂酸制备2（COD）]（COD = 环辛-1,5-二烯）和Ia，II或III（2当量）或IV（1当量）。[AuCl（tht）]（tht = 四氢噻吩）与1当量 的IA，得到[AUCL（IA）] 5。的桥的裂解[{的RuCl（μ-Cl）的（η 6 - p -cymene）}

  DOI：

  10.1039/b003759l

文献信息

• Isolation of a Hexanuclear Chromium Cluster with a Tetrahedral Hydridic Core and Its Catalytic Behavior for Ethylene Oligomerization
  作者：Ahmed Alzamly、Sandro Gambarotta、Ilia Korobkov、Muralee Murugesu、Jennifer J. H. Le Roy、Peter H.M. Budzelaar

  DOI：10.1021/ic500445b

  日期：2014.6.16

  A chromium complex [2-(NHCH2PPh2)C5H4N]CrCl3·THF2 (1) of the ligand PyNHCH2PPh2 has been synthesized, characterized, and examined for its catalytic behavior toward ethylene oligomerization. When complex 1 was treated with (i-Bu)3Al, an unprecedented divalent polyhydride chromium cluster μ,κ1,κ2,κ3-N,N,P-[2-(NCH2PPh2)C5H4N]Cr(μ-H)}4[(μ-Cl)Cr(μ-Cl)Al(i-Bu)2Cl]2 (2) was obtained. The complex contains

  合成了配体PyNHCH 2 PPh 2的铬络合物[2-（NHCH 2 PPh 2）C 5 H 4 N] CrCl 3 ·THF 2（1），表征并检查了其对乙烯低聚的催化行为。当复杂1中的溶液用（我-Bu）3的Al，前所未有的二价polyhydride铬簇μ，κ 1，κ 2，κ 3 - N，N-，P - [2-（NCH 2 PPH 2）C 5 ħ 4得到N] Cr（μ-H）} 4 [（μ-Cl）Cr（μ-Cl）Al（i- Bu）2 Cl] 2（2）。该络合物包含一个Cr 4 H 4核，该核被认为是抗磁性的，并且通过桥连作用与两个另外的二价高自旋Cr原子保持配位。两个铝酸盐残基保持键合至外围铬原子。在此讨论结构，磁性和电子构造。
• New pyridyl modified phosphines: Synthesis and late transition-metal coordination studies
  作者：Sean E. Durran、Martin B. Smith、Sophie H. Dale、Simon J. Coles、Michael B. Hursthouse、Mark E. Light

  DOI：10.1016/j.ica.2005.12.068

  日期：2006.6

  Using a phosphorus based Mannich condensation reaction the new pyridylphosphines 5-Ph2PCH2N(H)}C5H3(1-Cl) and 2-Ph2PCH2N(H)}C5H3(5-Br)N (1-Br) have been synthesised in good yields (60% and 88%, respectively) from Ph2PCH2OH and the appropriate aminopyridine. The ligands 1-Cl and 1-Br display variable coordination modes depending on the choice of late transition-metal complex used. Hence P-monodentate

  使用基于磷的曼尼希缩合反应，已经很好地合成了新的吡啶基膦5-Ph2PCH2N（H）} C5H3（1-Cl）和2-Ph2PCH2N（H）} C5H3（5-Br）N（1-Br）由Ph2PCH2OH和适当的氨基吡啶产生（分别为60％和88％）。取决于所使用的后期过渡金属络合物的选择，配体1-Cl和1-Br显示出不同的配位模式。因此已观察到单核络合物AuCl（1-Cl）（2），AuCl（1-Br）（3），RuCl2（对伞花烃）（1-Cl）（4），RuCl2（p -cymene）（1-Br）（5），RhCl2（Cp *）（1-Cl）（6），RhCl2（Cp *）（1-Br）（7），IrCl2（Cp *）（1-Cl） （8），IrCl2（Cp *）（1'-Cl）（8'），IrCl2（Cp *）（1-Br）（9），顺式/反式-PdCl2（1-Cl）（2）（10 ），顺式/反式-PdCl2（1-Br）
• Heterometallic Clusters with Cerium–Transition-Metal Bonding Supported by Nitrogen–Phosphorus Ligands
  作者：Xiong Sun、Jinghang Shen、Thayalan Rajeshkumar、Laurent Maron、Congqing Zhu

  DOI：10.1021/acs.inorgchem.3c02259

  日期：2023.10.2

  precursors, Pd(PPh3)4 and Pt(PPh3)4, with the cerium complex supported by VI generate heterometallic clusters [NCH2CH2NPiPr2}3Ce(μ-M)]2 (M = Pd, 2 and M = Pt, 3) featuring four Ce–M bonds; meanwhile, the bimetallic species [(PyNCH2PPh2)3Ce-M] (M = Ni, 5; M = Pd, 6; and M = Pt, 7) with a single Ce–M bond were isolated from the reactions of the cerium precursor 4 supported by VII with Ni(COD)2, Pd(PPh3)4

  众所周知，配体在金属-金属键配合物的构建中发挥着至关重要的作用。与涉及d区过渡金属的金属-金属键相比，对涉及f区稀土金属的金属-金属键的认识仍然远远落后。在此，我们报道了一系列具有铈-过渡金属键的配合物，这些配合物由两种氮-磷配体N[CH 2 CH 2 NHP i Pr 2 ] 3 ( VI )和PyNHCH 2 PPh 2 ( VII )支撑。零价第 10 族金属前体 Pd(PPh 3 ) 4和 Pt(PPh 3 ) 4与VI负载的铈配合物反应生成异金属簇 [NCH 2 CH 2 NP i Pr 2 } 3 Ce(μ- M)] 2 (M = Pd, 2且 M = Pt, 3 ) 具有四个 Ce-M 键；同时，从反应中分离出具有单Ce-M键的双金属物质[(PyNCH 2 PPh 2 ) 3 Ce-M] (M = Ni, 5 ; M = Pd, 6 ; and M = Pt, 7 ) VII负载的铈前体4分别为Ni(COD)
• Silver coordination complexes of 2-(diphenylphosphinomethyl)aminopyridine with weakly interacting counterions
  作者：Marissa K. Penney、Chelsea Potter、Mark A. Burroughs、Kevin K. Klausmeyer

  DOI：10.1016/j.poly.2015.09.048

  日期：2015.12

  A tri-functional ligand (Ph2PCH2)NH(2-C5H4N), DPAP-2, has been synthesized via the Mannich condensation reaction and its coordination behavior has been studied with various Ag(I) salts. The ligand is capable of P-coordination, P,N-chelation, and P,N-bridging to form Ag(I) complexes that range from discrete to 1-dimensional polymeric structures. In the 1:2 reaction of AgBF4 with DPAP-2, a 4-coordinate Ag(I) structure with P,N'-chelation is isolated (1). A counterion effect is observed in the equimolar reactions of AgX (2: X = BF4- and 3: X = tfa(-)) with DPAP-2, where the structures isolated are a dimer and a 1-dimensional polymer, respectively. When an equivalent of 5,5'-dimethyl-2,2'-dipyridyl (5,5'-dmbpy) was incorporated to the equimolar reaction of AgX and DPAP-2, three isostructural complexes resulted (4: X = and supplementary structures S1 : X = tfa(-), and 52: X = OTf-). In the 2:1:2 reaction of AgX (5: X = BF4- and 6: X = tfa(-)) with DPAP-2 and 5,5'-dmbpy, two distinct complexes are isolated where DPAP-2 adopts a syn- and anti-arrangement, respectively. (C) 2015 Elsevier Ltd. All rights reserved.
• Interaction of free functional group with platinum(II) center in cyclometalated complexes: A structural and photophysical property investigation
  作者：Jun-Feng Zhang、Gan Xin、Wen-Fu Fu、Han Xu、Li Li

  DOI：10.1016/j.ica.2009.10.021

  日期：2010.1

  A series of flexible multidentate ligands containing N,P-donor, 2-[N-(diphenylphosphino)methyl]amino-pyridine (L-1), 2-[N-bi-(diphenylphosphino)methyl]amino-pyridine (L-2), 2-[N-(diphenylphosphino)methyl]amino-7-methyl-1,8-naphthyridine (L-3) and 4-[(N-diphenylphosphino)methyl]amino-pyridine) (L-4) have been synthesized. The mono-and dinuclear cyclometalated platinum(II) complexes [Pt(C boolean AND N boolean AND N)L-1]ClO4 (HC boolean AND N boolean AND N = 6-phenyl-2,2'-bipyridine), [Pt-2(C boolean AND N boolean AND N)(2)L-1](ClO4)(2), [Pt-2(C boolean AND N boolean AND N)(2)L-2](ClO4)(2), [Pt(C boolean AND N boolean AND N)L-3]ClO4 and [Pt-2(C boolean AND N boolean AND N)(2)L-4](ClO4)(2) were prepared and their structures determined by X-ray crystal analysis. These complexes exhibit long-lived bright orange emissions ranging from 560 to 610 nm in the solid state at room temperature. In solution, dinuclear complexes have emissions with higher quantum yields than mononuclear complexes. This can be attributed to intramolecular interaction of free functional group with Pt(II) at axial position, resulting in the quenching of phosphorescence for platinum(II) complexes in the (MLCT)-M-3 excited state. (C) 2009 Elsevier B. V. All rights reserved.