malononitrile sodium salt

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: malononitrile sodium salt
• 英文别名: sodium dicyanomethanide
• 化学式: C₃HN₂Na
• 分子量: 88.0441
• InChiKey: CRINKDFEOJKZQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.84
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  malononitrile sodium salt 在 正丁基锂 作用下， 以 四氢呋喃 、 六甲基磷酰三胺 为溶剂， 生成 Dicyanmethandiid
  参考文献：
  名称：

  Vogt, Hans-Hubert; Gompper, Rudolf, Chemische Berichte, 1981, vol. 114, # 8, p. 2884 - 2897

  摘要：

  DOI：
• 作为产物：
  描述：

  丙二腈 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 0.17h， 生成 malononitrile sodium salt
  参考文献：
  名称：

  Synthesis, Crystal Structures, and Electrical Properties of Anion Radical Salts of Novel Electron Acceptors, 2,6-Dicyanomethylene-4-oxo-2,6-dihydrocyclopentadithiophene (CPDT-TCNQ) and Its Diselenophene Analogue (CPDS-TCNQ), Having Three Electron-Withdrawing Groups

  摘要：

  ion离子。

  DOI：

  10.1246/bcsj.77.463

文献信息

• Facile One-Pot Syntheses of Amidines and Enamines from Oximes via Beckmann Rearrangement Using Trifluoromethanesulfonic Anhydride
  作者：Tomofumi Takuwa、Tomofumi Minowa、Jim Yoshitaka Onishi、Teruaki Mukaiyama

  DOI：10.1246/bcsj.77.1717

  日期：2004.9

  Iminocarbocation intermediates were in situ-generated by treating various oximes with trifluoromethanesulfonic anhydride (Tf2O) in the presence of triethylamine in toluene and nucleophilic trapping with amines or sodium enolates under mild conditions afforded the corresponding amidines and enamines. Some of the thus-obtained enamines were converted to 2-substituted 4-oxo-3-quinolinecarboxylic acid derivatives by subsequent intramolecular Friedel–Crafts acylation.

  通过将各种肟在甲苯中与三氟甲磺酸酐（Tf2O）和三乙胺反应，原位生成亚胺碳正中间体，并在温和条件下用胺或烯醇钠捕捉，得到相应的脒和烯胺。部分获得的烯胺随后通过分子内 Friedel-Crafts 酰基化反应转化为 2-取代的 4-氧代-3-喹啉羧酸衍生物。
• Synthesis and Reactions of Some Pyrazine Derivatives
  作者：A. K. El-Shafei、A. M. El-Sayed、H. Abdel-Ghany、A. M. M. El-Saghier

  DOI：10.1080/00397919408010198

  日期：1994.7

  Abstract The pharmacodynamic properties1-3 of substituted amino pyrazines as well as their importance in the synthesis of pteridine and other polyfused heterocyclic systems is well known4,5. In this investigation we aim to prepare a new series of condensed heterocyclic systems containing the pyrazine nucleus.

  摘要 取代氨基吡嗪的药效学特性 1-3 以及它们在合成蝶啶和其他多稠合杂环系统中的重要性是众所周知的 4,5。在这项研究中，我们的目标是制备一系列新的含有吡嗪核的稠合杂环系统。
• Medicine comprising dicyanopyridine derivative
  申请人：——

  公开号：US20030232860A1

  公开（公告）日：2003-12-18

  Compounds having a high conductance-type of calcium-activated K channel opening effect and a smooth muscle relaxant effect for bladder based on the K-channel opening effect, which can be used in treating pollakiuria and urinary incontinence, are provided. 3,5-Dicyanopyridine derivatives or their salts.

  基于K通道开放效应的高导电型钙激活K通道开放效应和平滑肌松弛剂效应的化合物，可用于治疗尿频和尿失禁。提供3,5-二氰基吡啶衍生物或其盐。
• Preparation and Reactivities of (η³-1- and 2-Trimethylsiloxyallyl)Fe(CO)₂NO Complexes. Intermediates Functioning as Equivalents of β- and α-Acyl Carbocations and Acyl Carbanions
  作者：Keiji Itoh、Saburo Nakanishi、Yoshio Otsuji

  DOI：10.1246/bcsj.64.2965

  日期：1991.10

  (η3-1- and 2-Trimethylsiloxyallyl)Fe(CO)2NO complexes were prepared by the reaction of the corresponding siloxyallylic halides with Bu4N[Fe(CO)3NO]. These complexes reacted with both of carbon nucleophiles and carbon electrophiles preferentially at the less hindered sites of the allylic ligands. In these reactions, (η3-1-trimethylsiloxyallyl)Fe(CO)2NO complexes served as synthetically equivalent synthons

  (η3-1-和2-三甲基甲硅烷氧基烯丙基)Fe(CO)2NO配合物是通过相应的甲硅烷氧基烯丙基卤化物与Bu4N[Fe(CO)3NO]反应制备的。这些配合物优先与碳亲核试剂和碳亲电试剂在烯丙基配体的受阻较小的位点反应。在这些反应中，(η3-1-三甲基甲硅烷氧基烯丙基)Fe(CO)2NO 配合物作为 β-酰基碳正离子和 j8-酰基碳负离子和 (η3-2-三甲基甲硅烷氧基烯丙基)Fe(CO)2NO 配合物的合成等效合成子α-酰基碳正离子和α-酰基碳负离子。描述了反应的立体化学过程。
• Push-pull type of diphenoquinoid chromophores as novel near-infrared dyes
  作者：Shinobu Inoue、Yoshio Aso、Tetsuo Otsubo

  DOI：10.1039/a701626c

  日期：——

  Novel push-pull diphenoquinoid chromophores, in which one of the terminal positions carries a strong donor group, benzo-1,3-dithiol-2-ylidene, and the other a strong acceptor group, dicyanomethylene, are synthesized and show a strong absorption in the near-infrared region.

  新型推拉型二苯醌染料合成，其中一个末端位置带有强供体基团苯并-1,3-二硫啶-2-亚甲基，另一个则带有强受体基团二氰基亚甲基，显示出在近红外区域强烈的吸收。