1-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3,5-dibromobenzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3,5-dibromobenzene
• 英文别名: 2-(3,5-dibromophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
• 化学式: C₉H₄Br₂F₆O
• 分子量: 401.929
• InChiKey: FAYAIBPFYZDHEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  1-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3,5-dibromobenzene 、 正丁基锂 、 水 以97%的产率得到
  参考文献：
  名称：

  CHEN L. S.; CHEN G. J.; TAMBORSKI C., J. ORGANOMETAL. CHEM., 1981, 215, NO 3, 281-291

  摘要：

  DOI：
• 作为产物：
  描述：

  1,3,5-三溴苯 在 盐酸 、 正丁基锂 作用下， 以 乙醚 、 正己烷 为溶剂， 以60%的产率得到1-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-3,5-dibromobenzene
  参考文献：
  名称：

  NOVEL FLUORINE-CONTAINING DICARBOXYLIC ACIDS AND THEIR NOVEL POLYMER COMPOUNDS

  摘要：

  本发明公开了一种含氟的二羧酸，其化学式表示为（1），其中n表示1-4的整数，两个羧基不相邻于芳环上。通过将含氟二羧酸与共聚单体（例如，二氨基二醇）反应，可以获得线性聚合物化合物。通过热环化，这种线性聚合物化合物可以转化为具有优异特性的另一种聚合物化合物。

  公开号：

  US20090030173A1

文献信息

• Fluorine-Containing Dicarboxylic Acids and Their Novel Polymer Compounds
  申请人：NARIZUKA Satoru

  公开号：US20110282026A1

  公开（公告）日：2011-11-17

  A fluorine-containing dicarboxylic acid represented by formula (1), wherein n represents an integer of 1-4, and the two carboxylic groups are not adjacent to each other on the aromatic ring. It is possible to obtain a linear polymer compound by reacting the fluorine-containing dicarboxylic acid with a comonomer (e.g., diaminodiol). By thermal cyclization, this linear polymer compound can be converted into another polymer compound having superior characteristics.

  公式(1)表示的是含氟二羧酸，其中n代表1-4的整数，且两个羧基不相邻于芳香环上。通过将含氟二羧酸与共聚物（例如二氨基二醇）反应，可以得到线性聚合物化合物。通过热环化，这种线性聚合物化合物可以转化为具有卓越特性的另一种聚合物化合物。
• Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom
  申请人：Isono Yoshimi

  公开号：US20110301305A1

  公开（公告）日：2011-12-08

  According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride. [Chem. 134] AOCF 2 C-Q-CF 2 COA′  (M-1) In the above formula, Q represents a divalent organic group having a substituted or unsubstituted aromatic ring; and A and A′ each independently represent an organic group. This polymer exhibits a sufficiently low dielectric constant for use as a semiconductor protection film and has the capability of forming a film at a relatively low temperature of 250° C. or lower.

  根据本发明，通过将通式(M-1)的含氟二羧酸衍生物或含氟二羧酸酸酐与具有与含氟二羧酸衍生物或酸酐的羰基部分相对应的两到四个反应性基团的多官能化合物进行聚合缩合反应，可以得到一种聚合物。[Chem. 134]AOCF2C-Q-CF2COA′  (M-1)在上述公式中，Q代表具有取代或未取代芳香环的二价有机基团; A和A'各自独立地表示有机基团。该聚合物表现出足够低的介电常数，可用作半导体保护膜，并具有在相对较低的温度下（250℃或更低）形成膜的能力。
• Fluorine-containing dicarboxylic acids and their novel polymer compounds
  申请人：Central Glass Company, Limited

  公开号：US08003749B2

  公开（公告）日：2011-08-23

  Disclosed is a fluorine-containing dicarboxylic acid represented by formula (1), wherein n represents an integer of 1-4, and the two carboxylic groups are not adjacent to each other on the aromatic ring. It is possible to obtain a linear polymer compound by reacting the fluorine-containing dicarboxylic acid with a comonomer (e.g., diaminodiol). By thermal cyclization, this linear polymer compound can be converted into another polymer compound having superior characteristics.

  本文披露了一种含氟二羧酸，其化学式为(1)，其中n表示1-4的整数，两个羧基不相邻于芳环上。通过将含氟二羧酸与共聚物（例如二氨基二醇）反应，可以得到线性聚合物化合物。通过热环化，这种线性聚合物化合物可以转化为具有优异性能的另一种聚合物化合物。
• Fluorinated dicarboxylic acid derivative and polymer obtained therefrom
  申请人：Isono Yoshimi

  公开号：US08809451B2

  公开（公告）日：2014-08-19

  According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride. [Chem. 134] AOCF2C-Q-CF2COA′  (M-1) In the above formula, Q represents a divalent organic group having a substituted or unsubstituted aromatic ring; and A and A′ each independently represent an organic group. This polymer exhibits a sufficiently low dielectric constant for use as a semiconductor protection film and has the capability of forming a film at a relatively low temperature of 250° C. or lower.

  根据本发明，通过将通式为（M-1）的氟代二羧酸衍生物或氟代二羧酸酸酐与具有与氟代二羧酸衍生物或酸酐中的羰基相应反应的具有2至4个反应基团的多官能化合物进行聚合缩合，得到一种聚合物。[Chem. 134]AOCF2C-Q-CF2COA′  (M-1)在上述公式中，Q代表具有取代或未取代芳香环的二价有机基团；A和A'各自独立地代表一个有机基团。该聚合物表现出足够低的介电常数，可用作半导体保护膜，并具有在相对较低的温度（250℃或更低）下形成膜的能力。
• FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM
  申请人：Central Glass Company, Limited

  公开号：EP2395040A1

  公开（公告）日：2011-12-14

  According to the present invention, a polymer is obtained by polycondensation of a fluorinated dicarboxylic acid derivative of the general formula (M-1) or an acid anhydride of the fluorinated dicarboxylic acid with a polyfunctional compound having two to four reactive groups corresponding in reactivity to carbonyl moieties of the fluorinated dicarboxylic acid derivative or acid anhydride.         [Chem. 134] AOCF2C-Q-CF2COA'     (M-1) In the above formula, Q represents a divalent organic group having a substituted or unsubstituted aromatic ring; and A and A' each independently represent an organic group. This polymer exhibits a sufficiently low dielectric constant for use as a semiconductor protection film and has the capability of forming a film at a relatively low temperature of 250°C or lower.

  根据本发明，通过通式（M-1）的氟化二羧酸衍生物或氟化二羧酸的酸酐与多官能团化合物缩聚得到聚合物，多官能团化合物具有与氟化二羧酸衍生物或酸酐的羰基反应性相对应的 2 至 4 个活性基团。 [AOCF2C-Q-CF2COA' (M-1) 在上式中，Q 代表具有取代或未取代芳香环的二价有机基团；A 和 A'各自独立地代表一个有机基团。这种聚合物具有足够低的介电常数，可用作半导体保护膜，并能在 250°C 或更低的温度下形成薄膜。