10,12-tricosadiyn-1-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 10,12-tricosadiyn-1-amine
• 英文别名: 10,12-tricosadiynylamine；Tricosa-10,12-diyn-1-amine
• 化学式: C₂₃H₄₁N
• 分子量: 331.585
• InChiKey: RTENTPAAJZJPTN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  24
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  山梨酸 、 10,12-tricosadiyn-1-amine 以 氯仿 为溶剂， 生成 sorbic 10,12-tricosadiyneammonium
  参考文献：
  名称：

  PHOTORESPONSIVE POLYMER, BUILT-UP TYPE DIACETYLENE POLYMER, CRYSTALS OF AMMONIUM CARBOXYLATES, AND PROCESSES FOR PRODUCTION OF THEM

  摘要：

  公开号：

  EP1431266B1
• 作为产物：
  描述：

  10,12-二十三联炔酸 在 草酰氯 、 N,N-二甲基甲酰胺 、 ammonium hydroxide 、 lithium aluminium tetrahydride 作用下， 以 二氯甲烷 、 四氢呋喃 、 乙醚 为溶剂， 生成 10,12-tricosadiyn-1-amine
  参考文献：
  名称：

  通过使用自组装的二乙炔肽两亲物进行形态学依赖的细胞成像

  摘要：

  在此，提出了一种新型的含有双乙炔基序（DA 2 P）的阳离子双子肽两亲物，它在低浓度时会自组装成新型的and和波状纳米结构，在高浓度时会形成纳米纤维。有趣的是，DA 2 P组件可以聚合为荧光红相，但是只能在与HeLa细胞孵育期间聚合，这很可能是由于DA 2 P的二乙炔链在与细胞膜相互作用时发生了重组。红色荧光聚合的DA 2 P组件可以用作新型细胞成像探针。但是，只有囊泡，t和大肠状的DA可以将2 P组件转移到HeLa细胞中，而类似纳米纤维的DA 2 P组件则被细胞膜捕获并且不进入细胞。因此，观察到了形态学依赖性的细胞成像。

  DOI：

  10.1002/anie.201708168

文献信息

• Photoresponsive polymer, built-up type diacetylene polymer, crystals of ammonium carboxylates, and processes for production of them
  申请人：Matsumoto Akikazu

  公开号：US20050038284A1

  公开（公告）日：2005-02-17

  A crystal of carboxyl acid and at least one compound selected from the group consisting of amine and ammonia are mixed in an absence of a liquid medium. The carboxyl acid is conjugated diene such as (Z,Z)-muconic acid, the conjugated diene including a carboxyl group. The at least one nitrogen-containing compound selected from the group consisting of amine and ammonia is primary amine represented by RCH 2 NH 2 , where R is an aryl group, or is a normal alkyl group that contains five or more carbon atoms. Moreover, such amine that is a bivalent group and that is represented by -Ar-N═N-Ar′-, where Ar and Ar′ are independently aromatic hydrocarbon bivalent groups, is intercalated in a layered crystal of a polymer such as polymuconic acid, the layered crystal including a carboxyl group. In this way, a novel photoresponsive polymer is obtaind. Also obtained is a crystal of ammonium carboxylate including at least one kind of carboxyl acid and at least one kind of amine, at least one kind of compound selected from (i) the at least one kind of carboxyl acid and (ii) the at least one kind of amine being a diacetylene derivative. The crystal of ammonium carboxylate is subjected to light or heat, to obtain a built-up type diacetylene polymer.

  将羧酸晶体和至少一种从胺和氨组成的化合物混合，无需液体介质。羧酸是共轭二烯，例如（Z，Z）-巴苯二酸，共轭二烯包括一个羧基。从胺和氨组成的至少一种含氮化合物是由RCH2NH2表示的一级胺，其中R是芳基，或者是包含五个或更多碳原子的正常烷基。此外，这样的胺是一个双价基团，由-Ar-N═N-Ar'表示，其中Ar和Ar'是独立的芳香族碳氢化合物双价基团，插入到聚巴苯二酸等聚合物的层状晶体中，该层状晶体包括一个羧基。通过这种方式，获得了一种新型光响应性聚合物。同时，获得了至少包含一种羧酸和至少一种胺的羧酸铵晶体，其中来自（i）至少一种羧酸和（ii）至少一种胺的化合物中的至少一种是二乙炔衍生物。将羧酸铵晶体暴露于光或热以获得堆积型二乙炔聚合物。
• Photoresponsive polymer,built-up type diacetylene polymer, crystal of ammonium carboxylate, and method of manufacturing them
  申请人：Matsumoto Akikazu

  公开号：US20090253870A1

  公开（公告）日：2009-10-08

  A crystal of carboxyl acid and at least one compound selected from the group consisting of amine and ammonia are mixed in an absence of a liquid medium. The carboxyl acid is conjugated diene such as (Z,Z)-muconic acid, the conjugated diene including a carboxyl group. The at least one nitrogen-containing compound selected from the group consisting of amine and ammonia is primary amine represented by RCH 2 NH 2 , where R is an aryl group, or is a normal alkyl group that contains five or more carbon atoms. Moreover, such amine that is a bivalent group and that is represented by —Ar—N═N—Ar′—, where Ar and Ar′ are independently aromatic hydrocarbon bivalent groups, is intercalated in a layered crystal of a polymer such as polymuconic acid, the layered crystal including a carboxyl group. In this way, a novel photoresponsive polymer is obtained. Also obtained is a crystal of ammonium carboxylate including at least one kind of carboxyl acid and at least one kind of amine, at least one kind of compound selected from (i) the at least one kind of carboxyl acid and (ii) the at least one kind of amine being a diacetylene derivative. The crystal of ammonium carboxylate is subjected to light or heat, to obtain a built-up type diacetylene polymer.

  将羧酸晶体和至少一种从胺和氨组成的化合物混合在无液介质的情况下。羧酸是共轭二烯，例如(Z,Z)-巨环酸，共轭二烯包括一个羧基。从胺和氨组成的至少一种含氮化合物是由RCH2NH2表示的一级胺，其中R是芳基，或者是含有五个或更多碳原子的正常烷基。此外，这样的胺是一个双价基团，由—Ar—N═N—Ar′—表示，其中Ar和Ar′是独立的芳香族碳氢双价基团，被插入在聚合物的分层晶体中，例如聚巨环酸，分层晶体包括一个羧基。通过这种方式，获得了一种新型的光响应聚合物。同时获得了一种羧酸铵晶体，包括至少一种羧酸和至少一种胺，从(i)至少一种羧酸和(ii)至少一种胺中选出的至少一种化合物是二乙炔衍生物。将羧酸铵晶体经过光或热处理，获得一个堆积型二乙炔聚合物。
• POLY(METHYL METHACRYLATE)-SUPPORTED POLYDIACETYLENE FILMS AS COLORIMETRIC AND/OR FLUORESCENT DETECTORS
  申请人：B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY

  公开号：US20160041102A1

  公开（公告）日：2016-02-11

  Colorimetric and/or fluorescent detectors, which include a polydiacetylene (PDA) film deposited on a polymethylmetacrylate (PMMA) substrate. There are also colorimetric and/or fluorescent detectors which have a solid organic matrix comprising one or more PDAs deposited on the PMMA substrate, wherein the PDA includes polymerized units of one or more diacetylene monomers, and wherein the matrix further comprises at least one recognition element of an analyte. There are also methods for detecting analytes using this detector, uses thereof and a methods for its preparation.

  颜色计量和/或荧光检测器，包括沉积在聚甲基丙烯酸甲酯（PMMA）基板上的聚二烯烃（PDA）薄膜。还有一些颜色计量和/或荧光检测器，其具有包括沉积在PMMA基板上的一个或多个PDA的固体有机基质，其中PDA包括一个或多个二烯基单体的聚合单元，且基质进一步包括至少一种分析物的识别元素。还有使用该检测器检测分析物的方法，其用途以及其制备方法。
• Poly(methyl methacrylate)-supported polydiacetylene films as colorimetric and/or fluorescent detectors
  申请人：B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY

  公开号：US10101277B2

  公开（公告）日：2018-10-16

  Colorimetric and/or fluorescent detectors, which include a polydiacetylene (PDA) film deposited on a polymethylmetacrylate (PMMA) substrate. There are also colorimetric and/or fluorescent detectors which have a solid organic matrix comprising one or more PDAs deposited on the PMMA substrate, wherein the PDA includes polymerized units of one or more diacetylene monomers, and wherein the matrix further comprises at least one recognition element of an analyte. There are also methods for detecting analytes using this detector, uses thereof and a methods for its preparation.

  比色和/或荧光检测器，包括沉积在聚甲基丙烯酸甲酯（PMMA）基板上的聚二乙烯（PDA）薄膜。还有比色和/或荧光检测器，其固体有机基质包括沉积在 PMMA 基质上的一个或多个 PDA，其中 PDA 包括一个或多个二乙炔单体的聚合单元，基质还包括至少一个分析物的识别元素。此外，还有使用这种检测器检测分析物的方法、其用途及其制备方法。
• US7750084B2
  申请人：——

  公开号：US7750084B2

  公开（公告）日：2010-07-06