(R,S)-1-(1-Phenyl-1-propyl)imidazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R,S)-1-(1-Phenyl-1-propyl)imidazole
• 英文别名: 1-(1-Phenylpropyl)imidazole
• 化学式: C₁₂H₁₄N₂
• 分子量: 186.257
• InChiKey: UWCLNGVRDKXDSO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-苯丙醇 在 sodium hydroxide 、 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 、 二苯醚 、 乙醇 为溶剂， 反应 25.0h， 生成 (R,S)-1-(1-Phenyl-1-propyl)imidazole
  参考文献：
  名称：

  Stereospecific synthesis of 1-alkylimidazole derivatives via mitsunobu reactions

  摘要：

  4,5-Dicyanoimidazole has been reacted with racemic and enantiopure alcohols 1 under Mitsunobu conditions to give 1-alkyl-4,5-dicyanoimidazole derivatives 2, which in turn have been transformed by hydrolysis and decarboxylation into 1-alkylimidazoles 4 in good overall yield and high enantiomeric excess. The absolute stereochemistry of the compounds has been confirmed by synthesizing 4c through an independent route.

  DOI：

  10.1016/s0957-4166(00)86167-4

文献信息

• METHOD FOR PREPARING ACRYLONITRILE DIMER
  申请人：LG CHEM, LTD.

  公开号：EP3950667A1

  公开（公告）日：2022-02-09

  Provided is a method of preparing an acrylonitrile dimer, the method including: supplying an acrylonitrile monomer, a phosphorus-based catalyst, an alcohol solvent, and an ionic liquid to a reactor to perform a dimerization reaction to prepare a single-phase dimerization reaction product (S10); supplying a reactor discharge stream including the dimerization reaction product to a first distillation column, separating the alcohol solvent and an unreacted acrylonitrile monomer from an upper discharge stream, and supplying a lower discharge stream including an acrylonitrile dimer, the ionic liquid, and the phosphorus-based catalyst to a second distillation column (S20); and separating an upper discharge stream including the acrylonitrile dimer and separating a lower discharge stream including the ionic liquid and the phosphorus-based catalyst, in the second distillation column (S30).

  提供了一种制备丙烯腈二聚体的方法，该方法包括向反应器中加入丙烯腈单体、磷系催化剂、醇溶剂和离子液体，进行二聚反应，制备单相二聚反应产物（S10）；将包括二聚反应产物在内的反应器出料流供给第一蒸馏塔，从上层出料流中分离醇溶剂和未反应的丙烯腈单体，并将包括丙烯腈二聚体、离子液体和磷基催化剂在内的下层出料流供给第二蒸馏塔（S20）；在第二蒸馏塔 (S30) 中分离包括丙烯腈二聚体的上部排放流，并分离包括离子液体和磷基催化剂的下部排放流。
• Segmented reactor for homogeneous regeneration of spent ionic liquid
  申请人：Chevron U.S.A. Inc.

  公开号：US10005057B1

  公开（公告）日：2018-06-26

  We provide a segmented reactor for regenerating a spent acidic ionic liquid via a hydrogenation reaction and hydrocracking, comprising: no solid hydrogenation catalyst; a gas inlet on one side for feeding a gas feed comprising a hydrogen; a liquid inlet on an opposite side for feeding a spent acidic ionic liquid; partitions along an axis of the reactor that create segments, wherein each segment functions as a bubble column reactor; and an outlet from which a regenerated acidic ionic liquid flows out of the segmented reactor.

  我们提供了一种分段式反应器，用于通过加氢反应和加氢裂化再生废酸性离子液体，该反应器包括：无固体加氢催化剂；位于一侧的气体入口，用于输入包含氢气的气体进料；位于另一侧的液体入口，用于输入废酸性离子液体；沿反应器轴线形成的分段，其中每个分段用作气泡柱反应器；以及出口，再生的酸性离子液体从该出口流出分段式反应器。
• Alkylation of refinery pentenes with isobutane
  申请人：Chevron U.S.A. Inc.

  公开号：US10059639B2

  公开（公告）日：2018-08-28

  A process, comprising: providing an olefin feed comprising pentenes, butenes, and isopentane; and alkylating the olefin feed with isobutane using an acidic ionic liquid catalyst; wherein less than 5 mol % of C5 olefins in the olefin feed are converted to isopentane, and the alkylate gasoline has defined final boiling points and high RONs. A process comprising: alkylating an olefin feed comprising pentenes and isopentane, with isobutane using an acidic ionic liquid catalyst; wherein less than 5 mol % of C5 olefins in the olefin feed are converted to isopentane; and wherein an n-pentane product yield is low. An alkylate gasoline, comprising less than 0.1 wt % olefins and aromatics, less than 1.8 wt % C12+hydrocarbons, and greater than 60 wt % combined C8 and C9 hydrocarbons, wherein the trimethylpentane in the C8 hydrocarbons and the trimethylhexane in the C9 hydrocarbons are defined.

  一种工艺，包括：提供由戊烯、丁烯和异戊烷组成的烯烃进料；以及使用酸性离子液体催化剂将烯烃进料与异丁烷烷基化；其中烯烃进料中少于 5 摩尔%的 C5 烯烃转化为异戊烷，且烷基化汽油具有确定的终沸点和高 RONs。一种工艺，包括：使用酸性离子液体催化剂，将由戊烯和异戊烷组成的烯烃进料与异丁烷烷基化；其中烯烃进料中少于 5 摩尔%的 C5 烯烃转化为异戊烷；正戊烷产品收率低。一种烷基化汽油，包括小于 0.1 重量％的烯烃和芳烃，小于 1.8 重量％的 C12+ 碳氢化合物，以及大于 60 重量％的 C8 和 C9 碳氢化合物组合，其中 C8 碳氢化合物中的三甲基戊烷和 C9 碳氢化合物中的三甲基己烷是确定的。
• High viscosity index lubricants by isoalkane alkylation
  申请人：Chevron U.S.A. Inc.

  公开号：US10093594B2

  公开（公告）日：2018-10-09

  An isoalkane alkylate base oil and a process to make an isoalkane alkylate base oil having a VI higher than 90, comprising: a. selecting an isoalkane feed containing at least one isoalkane and an olefin feed containing at least one linear olefin such that a combined carbon number of the isoalkane feed and the olefin feed is from 20 to 60; and b. alkylating the isoalkane feed with the olefin feed in the presence of an acidic alkylation catalyst under alkylation conditions to make the isoalkane alkylate base oil having the VI higher than 90; wherein the isoalkane alkylate base oil has a kinematic viscosity at 100° C. from 2 to 30 mm2/s, a pour point less than 0° C., and a bromine index less than 2000 mg Br/100 g.

  一种异构烷烃烷基化基础油和一种制造VI值高于90的异构烷烃烷基化基础油的工艺，包括 a. 选择含有至少一种异构烷烃的异构烷烃进料和含有至少一种线性烯烃的烯烃进料，使异构烷烃进料和烯烃进料的碳数总和为 20 至 60；以及 b. 在酸性烷基化催化剂存在下，在烷基化条件下将异构烷烃进料与烯烃进料烷基化，以制备 VI 值高于 90 的异构烷烃烷基化基础油； 其中异构烷烃烷基化基础油在 100 摄氏度时的运动粘度为 2 至 30 mm2/s，倾点低于 0 摄氏度，溴指数低于 2000 mg Br/100 g。
• Integrated systems and processes for online monitoring of a chemical concentration in an ionic liquid
  申请人：Chevron U.S.A. Inc.

  公开号：US10094778B1

  公开（公告）日：2018-10-09

  An integrated system for monitoring a chemical concentration in an ionic liquid, comprising: a. an online FTIR instrument with an ATR window; b. a sample conditioning station that removes light hydrocarbons and produces a degassed ionic liquid that is analyzed by FTIR; and c. a solvent flushing system that flows solvent across the ATR window. Also, a process for monitoring the chemical concentration, comprising: a. degassing the ionic liquid in the sample conditioning station; b. passing the degassed ionic liquid over an ATR window; c. periodically redirecting a flow of the degassed ionic liquid via a bypass line or an on-off valve that isolates the ATR window from the process unit that elutes the ionic liquid; and d. flowing a solvent and a purging gas over the ATR window during the periodically redirecting step c); and e. resuming the passing of the degassed ionic liquid over the ATR window.

  用于监测离子液体中化学物质浓度的集成系统，包括 a. 带有 ATR 窗口的在线傅立叶变换红外光谱仪； b. 样品调节站，用于去除轻碳氢化合物并生成可进行傅立叶变换红外分析的脱气离子液体；以及 c. 溶剂冲洗系统，使溶剂流过 ATR 窗口。另外，一种监测化学浓度的工艺，包括 a. 在样品调节站中对离子液体进行脱气； b. 将脱气后的离子液体流过 ATR 窗口 c. 通过旁通管路或开关阀定期改变脱气离子液体的流向，将 ATR 窗口与洗脱离子液体的工艺单元隔离；以及 d. 在周期性重定向步骤 c) 期间，在 ATR 窗口上流动溶剂和净化气体；以及 e. 恢复脱气离子液体通过 ATR 窗口。