二(3,4,5-三甲氧基苯乙基铵)硫酸盐 | 642-73-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 二(3,4,5-三甲氧基苯乙基铵)硫酸盐
• 英文名称: Mescaline sulfate
• 英文别名: sulfuric acid;2-(3,4,5-trimethoxyphenyl)ethanamine
• CAS: 642-73-9
• 化学式: C11H19NO7S
• 分子量: 309.34
• InChiKey: AEEOQROQKAFCJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.56
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  137
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Serotonergic compositions and methods for treatment of mild cognitive impairment
  申请人：——

  公开号：US20020173511A1

  公开（公告）日：2002-11-21

  A method of treating Mild Cognitive Impairment has been discovered. The treatment method comprises administering an effective amount of a serotonergic agent, including, but not limited to dexnorfenfluramine. The agent can be any serotonergic agonist, partial agonist, serotonin reuptake inhibitor, or combinations of these agents. The treatment method also encompasses combinations of serotonergic agents and non-steroidal anti-inflammatory agents. The treatment method may also delay the onset of Mild Cognitive Impairment, dementia, or both.

  现已发现一种治疗轻度认知障碍的方法。该治疗方法包括施用有效量的血清素能制剂，包括但不限于右诺芬氟拉明。该药物可以是任何血清素能激动剂、部分激动剂、血清素再摄取抑制剂或这些药物的组合。治疗方法还包括血清素能药物和非甾体抗炎药物的组合。治疗方法还可以延缓轻度认知功能障碍、痴呆或两者的发生。
• US3932423A
  申请人：——

  公开号：US3932423A

  公开（公告）日：1976-01-13
• US4104027A
  申请人：——

  公开号：US4104027A

  公开（公告）日：1978-08-01
• [EN] SEROTONERGIC COMPOSITIONS AND METHODS FOR TREATMENT OF MILD COGNITIVE IMPAIRMENT<br/>[FR] COMPOSITIONS SEROTONINERGIQUES ET METHODES DE TRAITEMENT DE LA DEFICIENCE COGNITIVE LEGERE
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2002038142A2

  公开（公告）日：2002-05-16

  A method of treating Mild Cognitive Impairment has been discovered. The treatment method comprises administering an effective amount of a serotonergic agent, including, but not limited to dexnorfenfluramine. The agent can be any serotonergic agonist, partial agonist, serotonin reuptake inhibitor, or combinations of these agents. The treatment method also encompasses combinations of serotonergic agents and non-steroidal anti-inflammatory agents. The treatment method may also delay the onset of Mild Cognitive Impairment, dementia, or both.
• [EN] METHODS FOR TREATING MILD TRAUMATIC BRAIN INJURY, POST TRAUMATIC STRESS DISORDER AND MILD TRAUMATIC BRAIN INJURY<br/>[FR] MÉTHODES DE TRAITEMENT D'UNE LÉSION CÉRÉBRALE TRAUMATIQUE LÉGÈRE, D'UN TROUBLE DE STRESS POST-TRAUMATIQUE ET D'UNE LÉSION CÉRÉBRALE TRAUMATIQUE LÉGÈRE
  申请人：LOBE SCIENCES LTD

  公开号：WO2021216489A1

  公开（公告）日：2021-10-28

  Methods and compositions for treating mTBI, PTSD or mTBI with PTSD with psychedelic agents and N-acetylcysteine are provided. Nasal mist transducers for administration of one or more pharmaceutically active ingredients such as these as fine mist particles at preselected dosages and times are also provided.