N-allyl-N-phenethylprop-2-en-1-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-allyl-N-phenethylprop-2-en-1-amine
• 英文别名: N,N-diallyl phenylethylamine；diallyl-phenethyl-amine；Diallyl-β-phenaethylamin；Diallyl-phenaethyl-amin；N-(2-phenylethyl)-N-prop-2-enylprop-2-en-1-amine
• 化学式: C₁₄H₁₉N
• 分子量: 201.312
• InChiKey: RBLOLLQSDUBDFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (E)-N,N-diallyl-2-phenylethenamine 在 sodium cyanoborohydride 、 溶剂黄146 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 N-allyl-N-phenethylprop-2-en-1-amine
  参考文献：
  名称：

  Hydroamination of terminal alkynes with secondary amines catalyzed by copper: regioselective access to amines

  摘要：

  一种简单方便的铜催化芳基乙炔与二级胺的氢胺化反应已经进行，经过氢胺化产物（E-烯胺）还原后，简单地获得脂肪胺的途径。

  DOI：

  10.1039/c5cc02677f

文献信息

• Cesium Effect:  High Chemoselectivity in Direct N-Alkylation of Amines
  作者：Ralph Nicholas Salvatore、Advait S. Nagle、Kyung Woon Jung

  DOI：10.1021/jo010643c

  日期：2002.2.1

  A novel method for the mono-N-alkylation of primary amines, diamines, and polyamines was developed using cesium bases in order to prepare secondary amines efficiently. A cesium base not only promoted alkylation of primary amines but also suppressed overalkylations of the produced secondary amines. Various amines, alkyl bromides, and alkyl sulfonates were examined, and the results demonstrated this

  为了有效地制备仲胺，使用铯碱开发了一种用于伯胺，二胺和多胺的单N-烷基化的新方法。铯碱不仅促进伯胺的烷基化，而且抑制产生的仲胺的过度烷基化。检查了各种胺，烷基溴化物和烷基磺酸盐，结果表明该方法具有较高的化学选择性，比单烷基化更有利于单-N-烷基化。特别地，使用空间要求高的底物或氨基酸衍生物可专门提供仲胺，在拟肽合成中具有广泛的应用。
• Catalytic Removal of <i>N</i>-Allyloxycarbonyl Groups Using the [CpRu(IV)(π-C₃H₅)(2-quinolinecarboxylato)]PF₆ Complex. A New Efficient Deprotecting Method in Peptide Synthesis
  作者：Shinji Tanaka、Hajime Saburi、Takanori Murase、Masahiro Yoshimura、Masato Kitamura

  DOI：10.1021/jo060445r

  日期：2006.6.1

  N-allylation from the corresponding N-allyloxycarbonyl (N-AOC) compounds by using a catalytic amount of [CpRu(IV)(π-C3H5)(2-quinolinecarboxylato)]PF6 in the presence of 1 molar amount of trifluoromethanesulfonic acid, the general utility of which has been demonstrated by the efficient synthesis of a collagen protein unit tripeptide, Pro-Pro-Gly.

  通过使用催化量的[CpRu（IV）（π-C），即使在空间上要求不高且亲核性很高的仲胺等各种胺也无需从相应的N-烯丙氧羰基（N -AOC）化合物上脱羧化N-烯丙基化，即可有效地脱保护。在1摩尔量的三氟甲磺酸存在下的3 H 5）（2-喹啉羧基甲酰基）] PF 6，其一般用途已经通过有效合成胶原蛋白单元三肽Pro-Pro-Gly得到了证明。
• Method for Producing Fluorine-Containing Alkyl (Meth)Acrylate
  申请人：Yamaguchi Masao

  公开号：US20090023948A1

  公开（公告）日：2009-01-22

  The present invention discloses a method for producing a fluorine-containing alkyl (meth)acrylate represented by the following general formula (2): Rf—(CH 2 ) k -[-A-(CH 2 ) l —] m —OCOCR═CH 2 (2) (wherein R is a hydrogen atom or a methyl group), characterized by reacting a fluorine-containing alcohol represented by the following general formula (1): Rf—(CH 2 ) k -[-A-(CH 2 ) l —] m —OH  (1) (wherein Rf is a perfluoroalkyl group having 1 to 21 carbon atoms; A is S, SO or SO 2 ; k is 0, 1 or 2; 1 is k, 2 or 3; m is 0 or 1; however, a case of k=0 and m=0 is excluded), (meth)acrylic acid, and a sulfonic acid halide in the presence of a base containing at least one kind of tertiary amine.

  本发明揭示了一种生产由下述通用式（2）表示的含氟烷基（甲基）丙烯酸酯的方法：Rf—（CH2）k-[-A-（CH2）l—]m—OCOCR═CH2（2）（其中R为氢原子或甲基），其特征在于在至少含有一种三级胺的碱存在下，通过将下述通用式（1）表示的含氟醇：Rf—（CH2）k-[-A-（CH2）l—]m—OH（1）（其中Rf为具有1至21个碳原子的全氟烷基；A为S、SO或SO2；k为0、1或2；l为k、2或3；m为0或1；但排除k=0且m=0的情况），与（甲）丙烯酸和磺酸卤在碱的存在下进行反应。
• Articles and methods for treating fabrics in dryer
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0319094A2

  公开（公告）日：1989-06-07

  Dryer-added fabric conditioning articles and methods utilizing a fabric conditioning composition which is released in the dryer by a dispensing means, said fabric conditioning composition comprising an improved uniform and stable mixture of: a polymeric soil release agent, particularly a higher molecular weight or a higher viscosity polymeric soil release agent, a dispersing aid, a fabric softening agent, and a viscosity control agent.

  利用织物调理组合物的烘干机添加织物调理物品和方法，该组合物在烘干机中通过分配装置释放，所述织物调理组合物包括一种改进的均匀稳定混合物：聚合物脱土剂，特别是分子量较高或粘度较高的聚合物脱土剂、分散助剂、织物柔软剂和粘度控制剂。
• Improvements in or relating to polymeric compounds
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0358400A2

  公开（公告）日：1990-03-14

  A polymeric compound is derived from a polyhydric material and has pendant sulphonate groups of the general formula where X is an aliphatic, aromatic, carbocylic or heterocyclic group; Y is hydrogen, halogen or an alkyl, aryl, alkoxy, aryloxy or aralkyl group, CO₂⁻Z⁺, CO₂R or SO₃⁻Z⁺; Z⁺ is a cationic counter ion and R is hydrogen, alkyl, alkylene, aryl or aralkyl group.

  一种聚合化合物来源于多水材料，并具有通式如下的悬垂磺酸基团 其中，X 是脂肪族、芳香族、羰基或杂环基；Y 是氢、卤素或烷基、芳基、烷氧基、芳氧基或芳烷基、CO₂-Z⁺、CO₂R 或 SO₃-Z⁺；Z⁺ 是阳离子反离子，R 是氢、烷基、亚烷基、芳基或芳烷基。