5-chloro-4-(3-methoxy-4-(4-fluorophenyloxy)phenylacetylamino)-1-methylpyrazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-chloro-4-(3-methoxy-4-(4-fluorophenyloxy)phenylacetylamino)-1-methylpyrazole
• 英文别名: N-(5-chloro-1-methylpyrazol-4-yl)-2-[4-(4-fluorophenoxy)-3-methoxyphenyl]acetamide
• 化学式: C₁₉H₁₇ClFN₃O₃
• 分子量: 389.814
• InChiKey: ICEZFZSDYPQFOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  65.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5-chloro-4-(3-methoxy-4-(4-fluorophenyloxy)phenylacetylamino)-1-methylpyrazole 、 氯甲基乙醚 在 sodium hydroxide 、 苄基三乙基氯化铵 作用下， 以 二氯甲烷 为溶剂， 以52%的产率得到5-chloro-4-(N-ethoxymethyl-N-(3-methoxy-4-(4-fluorophenyloxy)phenylacetyl)amino)-1-methyl-pyrazole
  参考文献：
  名称：

  EP1319657

  摘要：

  公开号：
• 作为产物：
  描述：

  5-chloro-1-methyl-1H-pyrazol-4-amine 、 3-methoxy-4-(4-fluorophenyloxy) phenylacetic acid 、 2-氯-1-甲基吡啶碘化物 、 甲烷 在 三乙胺 作用下， 以 四氢呋喃 、 乙酸乙酯 为溶剂， 以65%的产率得到5-chloro-4-(3-methoxy-4-(4-fluorophenyloxy)phenylacetylamino)-1-methylpyrazole
  参考文献：
  名称：

  EP1319657

  摘要：

  公开号：

文献信息

• N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：EP1319657A1

  公开（公告）日：2003-06-18

  N-(4-Pyrazolyl)amide derivatives of the general formula (I), exhibiting excellent control activities as bacteriocides, fungicides, insecticides, or nematicides for agricultural and horticultural use; chemicals for agricultural and horticultural use; and usage of the same, wherein R1 is H, optionally halogenated (C1-C6)alkyl, optionally substituted phenylsulfonyl, optionally substituted phenyl, or the like; R2 and R3 are each H, halogeno, CN, NO2, OH, SH, NH2, optionally halogenated (C1-C6)alkyl, optionally substituted phenyl, or the like; R4 is H, optionally halogenated (C1-C6)alkyl, cyano(C1-C6)alkyl, optionally substituted phenyl(C1-C6)alkyl, or the like; R5 is a group of formula (a) or (b), optionally substituted naphthyl, or the like; and Y is (C1-C6)alkylene, optionally halogenated (C1-C6)alkyl(C1-C6)alkyl(C1-C6)alkylene, or the like.

  通式(I)的 N-(4-吡唑基)酰胺衍生物、 其中 R1 是 H、任选卤代（C1-C6）烷基、任选取代的苯磺酰基、任选取代的苯基或类似物；R2和R3各自是H、卤代、CN、NO2、OH、SH、NH2、任选卤代的(C1-C6)烷基、任选取代的苯基或类似物；R4是H、任选卤代的(C1-C6)烷基、氰基(C1-C6)烷基、任选取代的苯基(C1-C6)烷基或类似物；R5是式(a)或(b)的基团、任选取代的萘基或类似物；Y是(C1-C6)亚烷基、任选卤代的(C1-C6)烷基(C1-C6)烷基或类似物。
• N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same
  申请人：——

  公开号：US20040043904A1

  公开（公告）日：2004-03-04

  N-(4-Pyrazolyl)amide derivatives of the general formula (I), 1 exhibiting excellent control activities as bacteriocides, fungicides, insecticides, or nematicides for agricultural and horticultural use; chemicals for agricultural and horticultural use; and usage of the same, wherein R 1 is H, optionally halogenated (C 1 -C 6 )alkyl, optionally substituted phenylsulfonyl, optionally substituted phenyl, or the like; R 2 and R 3 are each H, halogeno, CN, NO 2 , OH, SH, NH 2 , optionally halogenated (C 1 -C 6 )alkyl, optionally substituted phenyl, or the like; R 4 is H, optionally halogenated (C 1 -C 6 )alkyl, cyano(C 1 -C 6 )alkyl, optionally substituted phenyl(C 1 -C 6 )alkyl, or the like; R 5 is a group of formula (a) or (b), optionally substituted naphthyl, or the like; and Y is (C 1 -C 6 )alkylene, optionally halogenated (C 1 -C 6 )alkyl(C 1 -C 6 )alkyl(C 1 -C 6 )alkylene, or the like.
• EP1319657
  申请人：——

  公开号：——

  公开（公告）日：——